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Oxidative Stability in Lipid Formulations: a Review of the Mechanisms, Drivers, and Inhibitors of Oxidation
The importance of lipid-based formulations in addressing solubility and ultimately the bioavailability issues of the emerging drug entities is...
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Epilepsy and Oxidative Stress
Epilepsy is one of the most common neurological condition reported worldwide. Oxidative stress and neuroinflammation have been strongly associated...
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Effect of Lipid Vehicles on Solubility, Stability, and Topical Permeation of Delta-9-Tetrahydrocannabinol
Delta-9-tetrahydrocannabinol (THC) is one of the most effective antinociceptive agents used in the treatment of peripheral neuropathy. THC is highly...
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UCP1 alleviates renal interstitial fibrosis progression through oxidative stress pathway mediated by SIRT3 protein stability
BackgroundRenal interstitial fibrosis is a common pathway for the progressive development of chronic renal diseases (CKD) with different etiology,...
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Defense Against Oxidative Stress: Nrf2-ARE Pathway
Reactive chemical intermediates, including reactive oxygen and nitrogen species and free radicals, are formed during foreign compound metabolic...
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Lipid-Based Nanocarriers for the Delivery of Phytoconstituents
Over the last decade, lipid-based nanocarriers have proven to be a good carrier for many pharmaceutical medications. Different types of lipid-based...
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Solid Lipid Nanoparticles for the Management of Allergic Airway Diseases
The allergic airway diseases comprise both allergic rhinitis and asthma which are amongst the top three ailments of the twenty-first century...
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Evaluating Motor Dysfunction and Oxidative Stress Induced by Trichloroethylene in Wistar Rats
Trichloroethylene, a chlorinated solvent widely used as a degreasing agent, is a common environmental contaminant. Emerging evidence suggests that...
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Mitochondrial/Oxidative Stress Biomarkers in Huntington’s Disease
Huntington’s disease (HD) is a hereditary neurodegeneration caused by a mutation in the HTT gene, leading to mutated huntingtin protein aggregation....
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Mechanistic and Therapeutic Crosstalk of Lipid Peroxidation in Oxidative Stress and Breast Cancer
Breast cancer is the most frequently diagnosed and leading cancer with the highest morbidity worldwide in women. In the past few decades, researchers...
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Mechanistic and Therapeutic Crosstalk of Lipid Peroxidation in Oxidative Stress and Breast Cancer
Breast cancer is the most frequently diagnosed and leading cancer with the highest morbidity worldwide in women. In the past few decades, researchers...
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Oxidative Stress and Metals in Alzheimer’s Disease
Alzheimer’s disease (AD) is one of the progressive neurodegenerative disorders allied with genetic, lifestyle, and environmental factors and mainly...
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Transcriptomic Analysis of Lipid Metabolism Genes in Alzheimer’s Disease: Highlighting Pathological Outcomes and Compartmentalized Immune Status
The dysregulation of lipid metabolism has been strongly associated with Alzheimer’s disease (AD) and has intricate connections with various aspects...
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Oxidative Medicine and Novel Pharmacological Treatment Approaches in Liver Disease
The function of the liver is to carry out detoxification of xenobiotics, metabolism of amino acids and proteins, synthesis of bile from cholesterol,...
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Small molecule–engineered nanoassembly for lipid peroxidation–amplified photodynamic therapy
Photodynamic therapy (PDT), extensively explored as a non-invasive and spatio-temporal therapeutic modality for cancer treatment, encounters...
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Oxidative Stress Biomarkers in Exercise
An increase in the amount of free radicals resulting from exercise has been reported in various studies on humans and experimental animals to date....
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Promises of Lipid-Based Nanocarriers for Delivery of Dimethyl Fumarate to Multiple Sclerosis Brain
Multiple sclerosis (MS) is a neurodegenerative autoimmune disorder of the central nervous system (CNS) infecting 2.5 million people worldwide. It is...
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Oxidative Stress Biomarkers in Exercise
An increase in the amount of free radicals resulting from exercise has been reported in various studies on humans and experimental animals to date....
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Targeting Oxidative Stress in Cancer
Oxidative stress plays an immense role in modulating all aspects of cancer and also correlated with the different types of carcinogenesis in the form...
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Malnutrition-Induced Oxidative Stress in Nervous System and Its Health Implications
Neural development, especially in the brain, is a rapid metabolic process that demands a huge supply of building blocks and energy. Nutrients are...