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Lentinan has a beneficial effect on cognitive deficits induced by chronic Toxoplasma gondii infection in mice
BackgroundToxoplasma gondii ( T. gondii ) is increasingly considered a risk factor for neurodegenerative diseases. However, there is only limited...
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Lentinan alleviates arsenic-induced hepatotoxicity in mice via downregulation of OX40/IL-17A and activation of Nrf2 signaling
BackgroundArsenic, existing ubiquitously in soil, drinking water, or food, is well known to be an environmental pollutants concerned by European Food...
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Lentinan enhances the antitumor effects of Delta-like 1 via neutrophils
BackgroundSelective activation of Delta-like 1 (DLL1)-Notch signaling is a new approach to activate CD8 + T cell and suppress tumor growth, while the...
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Immunomodulatory Effect of Lentinan on Aberrant T Subsets and Cytokines Profile in Non-small Cell Lung Cancer Patients
As a purified active component from traditional Chinese medicine, lentinan administration can be applied as beneficial chemo-immunotherapy for...
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Stimulators of immunogenic cell death for cancer therapy: focusing on natural compounds
A growing body of evidence indicates that the anticancer effect of the immune system can be activated by the immunogenic modulation of dying cancer...
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Proteomic Research on the Therapeutic Properties of Medicinal Mushrooms
According to estimates, more than 800 mushroom species have been confirmed to possess various pharmacological properties. While the primary research... -
Lentinan inhibits tumor angiogenesis via interferon γ and in a T cell independent manner
BackgroundAntiangiogenic agents are commonly used in lung and colon cancer treatments, however, rapid development of drug resistance limits their...
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Are chemical compounds in medical mushrooms potent against colorectal cancer carcinogenesis and antimicrobial growth?
After cardiovascular diseases, cancer is the second main cause of death globally. Mushrooms have been demonstrated to contain amalgamation with...
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Mushrooms – From Traditional Remedies to the Modern Therapeutics
Although the living standard and life expectancy have been increasing significantly, we face numerous arising challenges in modern medicine, such as... -
Medicinal Mushrooms for Respiratory Health
Chronic respiratory disorders (CRDs) have been a key threat globally to the public health system. An estimated 545 million cases worldwide could... -
Therapeutic potential of natural products in inflammation: underlying molecular mechanisms, clinical outcomes, technological advances, and future perspectives
Chronic inflammation is a common underlying factor in many major diseases, including heart disease, diabetes, cancer, and autoimmune disorders, and...
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Mechanisms Involved in Edible Mushrooms’ Health Beneficial Effects
Despite the mushrooms’ long application history, only in the last century, more data regarding their nutritional qualities and beneficial effects... -
Therapeutic and Prophylactic Potential of Medicinal Mushrooms in COVID-19
Medicinal mushrooms have been used for thousands of years as natural medicine. The bioactive constituents found within the mushroom products are... -
Polysaccharides in Cancer Therapy
Over the past decade, mounting evidences pointing to the substantial contributions of polysaccharides in biological phenomenon like cell-cell... -
Mycotherapeutics Reduce Nephrotoxicity and Renal Diseases
Acute/chronic exposure to endogenous and exogenous toxins, aging, and comorbidities simultaneously increase the prevalence of nephronal dysfunction... -
Boosting antitumor efficacy using docetaxel-loaded nanoplatforms: from cancer therapy to regenerative medicine approaches
The intersection of nanotechnology and pharmacology has revolutionized the delivery and efficacy of chemotherapeutic agents, notably docetaxel, a key...
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Biological Activities of Some Edible Mushrooms
Since ancient times, mushrooms have been a valuable food source and traditional medicine worldwide. Edible mushrooms possess high nutritional value... -
Influences of Edible Mushrooms on Dynamic and Diversity of Gut Microbiota
The consumption of mushrooms impacts the immune system and gut microbiota due to the presence of prebiotic and probiotic components found in... -
The underlying mechanisms of cisplatin-induced nephrotoxicity and its therapeutic intervention using natural compounds
Cisplatin is an effective chemotherapeutic drug widely used for the treatment of various solid tumors; however, its clinical use and efficacy are...