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Detection of human neurotropic JCPyV DNA sequence in pediatric anaplastic xanthoastrocytoma
Due to its peculiar histopathological findings, pleomorphic xanthoastrocytoma (PXA), a rare cerebral tumor of young adults with a slow growth and a...
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The differential presence of human polyomaviruses, JCPyV and BKPyV, in prostate cancer and benign prostate hypertrophy tissues
BackgroundStudies have shown that human polyomavirus infection may be associated with various human cancers. We investigated the potential...
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Inhibition of orthotopic castration-resistant prostate cancer growth and metastasis in mice by JC VLPs carrying a suicide gene driven by the PSA promoter
Metastatic castration-resistant prostate cancer (mCRPC) is challenging to treat. Virus-like particles (VLPs), originating from JC polyomavirus...
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Undetectable JC virus CSF PCR in patients with JC virus-induced progressive multifocal leukoencephalopathy
The diagnosis of progressive multifocal leukoencephalopathy (PML) is based on a combination of clinical, radiographic, and laboratory findings....
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Traces of JC polyomavirus in papillary thyroid cancer: a comprehensive study in Iran
BackgroundJC polyomavirus (JCPyV) is known to induce solid tumors such as astrocytomas, glioblastomas, and neuroblastomas in experimental animals,...
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BK and JC polyomaviruses and risk of urothelial bladder carcinoma: a preliminary study in the northern shores of Persian Gulf, Iran
BackgroundBladder cancer is a challenging public health concern in South of Iran because of its high prevalence and the related medical expenses....
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Rapid-progressing progressive multifocal leukoencephalopathy in two patients newly diagnosed with HIV: case series and review of literature
The JC Polyomavirus (JCPyV) is a virus of global distribution and is usually kept under control by the immune system. In patients with AIDS, a latent...
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Progressive multifocal leukoencephalopathy: a retrospective study of the last 12 years in a tertiary-care hospital
Our study aims to report on the demographic, incidence rate (IR), clinical, and microbiological characteristics of PML patients diagnosed in our...
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JCPyV NCCR analysis in PML patients with different risk factors: exploring common rearrangements as essential changes for neuropathogenesis
BackgroundDuring severe immunosuppression or treatment with specific biological drugs, human polyomavirus JC (JCPyV) may establish a lytic infection...
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Prevalence of 13 polyomaviruses in actinic keratosis and matched healthy skin samples of immunocompetent individuals
BackgroundActinic keratosis (AK) is a precursor of cutaneous squamous cell carcinoma (cSCC). UV radiation is the major risk factor for AK, but...
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Suppression of bone metastatic castration-resistant prostate cancer cell growth by a suicide gene delivered by JC polyomavirus-like particles
Prostate cancer is one of the most common cancers in men. The heterogeneity and mutations exhibited by prostate cancer cells often results in the...
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Assessment of Microbiological Quality of Fresh Vegetables and Oysters Produced in Buenos Aires Province, Argentina
Fresh vegetables and shellfish are prone to microbial contamination through irrigation or breeding with sewage-polluted waters, as well as by...
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Comparison of Three Viral Nucleic Acid Preamplification Pipelines for Sewage Viral Metagenomics
Viral metagenomics is a useful tool for detecting multiple human viruses in urban sewage. However, more refined protocols are required for its...
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Wastewater-based epidemiology applied at the building-level reveals distinct virome profiles based on the age of the contributing individuals
BackgroundHuman viruses released into the environment can be detected and characterized in wastewater. The study of wastewater virome offers a...
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Cerebrospinal fluid analysis in 108 patients with progressive multifocal leukoencephalopathy
BackgroundProgressive multifocal leukoencephalopathy (PML) is caused by an opportunistic infection with JC polyoma virus (JCPyV) and mainly affects...
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Understanding the link between neurotropic viruses, BBB permeability, and MS pathogenesis
Neurotropic viruses can infiltrate the CNS by crossing the blood–brain barrier (BBB) through various mechanisms including paracellular,...
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Histone deacetylase III interactions with BK polyomavirus large tumor antigen may affect protein stability
BackgroundHuman polyomavirus BK (BKPyV) causes associated nephropathy and contributes to urinary tract cancer development in renal transplant...
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Investigation of simian virus 40 (SV40) and human JC, BK, MC, KI, and WU polyomaviruses in glioma
The gliomagenesis remains not fully established and their etiological factors still remain obscure. Polyomaviruses were detected and involved in...
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Merkel cell polyomavirus detected in head and neck carcinomas from Chile
BackgroundThe role of human polyomaviruses (HPyVs) in epithelial tumors such as head and neck carcinomas (HNSCCs) including oral and oropharyngeal...
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Analysis of viruses present in urine from patients with interstitial cystitis
The question of whether some cases of interstitial cystitis may have an infectious etiology has been debated for some time. Previous studies have...
