Search
Search Results
-
Inter-individual, hemispheric and sex variability of brain activations during numerosity processing
Numerosity perception is a fundamental and innate cognitive function shared by both humans and many animal species. Previous research has primarily...
-
Modelling inter-individual variability in acute and adaptive responses to interval training: insights into exercise intensity normalisation
PurposeTo investigate the influence of exercise intensity normalisation on intra- and inter-individual acute and adaptive responses to an interval...
-
-
In vitro–in silico-based prediction of inter-individual and inter-ethnic variations in the dose-dependent cardiotoxicity of R- and S-methadone in humans
New approach methodologies predicting human cardiotoxicity are of interest to support or even replace in vivo-based drug safety testing. The present...
-
Influence of the microbiome, diet and genetics on inter-individual variation in the human plasma metabolome
The levels of the thousands of metabolites in the human plasma metabolome are strongly influenced by an individual’s genetics and the composition of...
-
Human macrophages infected with Egyptian Rousette bat-isolated Marburg virus display inter-individual susceptibility and antiviral responsiveness
Marburg virus (MARV) is a highly pathogenic filovirus and a causative agent of sporadic zoonotic viral hemorrhagic fever outbreaks with high case...
-
Personality Moderates Intra-Individual Variability in EEG Microstates and Spontaneous Thoughts
Variability in brain activity that persists after accounting for overt behavioral and physiological states is often considered noise and controlled...
-
Inter-individual variation in chlorpyrifos toxicokinetics characterized by physiologically based kinetic (PBK) and Monte Carlo simulation comparing human liver microsome and Supersome™ cytochromes P450 (CYP)-specific kinetic data as model input
The present study compares two approaches to evaluate the effects of inter-individual differences in the biotransformation of chlorpyrifos (CPF) on...
-
Using Clustering to Examine Inter-individual Variability in Topography of Auditory Event-Related Potentials in Autism and Typical Development
Although prior studies have compared sensory event-related potential (ERP) responses between groups of autistic and typically-develo**...
-
Population Pharmacodynamic Modeling Using the Sigmoid Emax Model: Influence of Inter-individual Variability on the Steepness of the Concentration–Effect Relationship. a Simulation Study
The relationship between the concentration of a drug and its pharmacological effect is often described by empirical mathematical models. We...
-
Assessing Differential Variability of High-Throughput DNA Methylation Data
Purpose of ReviewDNA methylation (DNAm) is essential to human development and plays an important role as a biomarker due to its susceptibility to...
-
Glucose Variability Measures in Critical Care
Hyperglycemia commonly occurs in critically ill patients. Research over the past 20 years has evolved to indicate that glucose variability – not...
-
Individual variability in the nonlinear development of the corpus callosum during infancy and toddlerhood: a longitudinal MRI analysis
The human brain spends several years bootstrap** itself through intrinsic and extrinsic modulation, thus gradually develo** both spatial...
-
Ethnogeographic and inter-individual variability of human ABC transporters
ATP-binding cassette (ABC) transporters constitute a superfamily of 48 structurally similar membrane transporters that mediate the ATP-dependent...
-
White matter variability, cognition, and disorders: a systematic review
Inter-individual differences can inform treatment procedures and—if accounted for—have the potential to significantly improve patient outcomes....
-
Modeling kinematic variability reveals displacement and velocity based dual control of saccadic eye movements
Noise is a ubiquitous component of motor systems that leads to behavioral variability of all types of movements. Nonetheless, systems-based models...
-
Untangling Absorption Mechanisms and Variability in Bioequivalence Studies Using Population Analysis
PurposeBoth inter-individual (IIV) and inter-occasion (IOV) variabilities are observed in bioequivalence studies. High IOV may be a cause of problems...
-
Signal in the noise: Altered brain activation among adolescent alcohol users detected via the analysis of intra-individual variability1
RationaleUnlike its average level, the variability in brain activation over time or trials can capture subtle and brief disruptions likely to occur...
-
Impact of distinct cognitive domains on gait variability in individuals with mild cognitive impairment and dementia
BackgroundGait variability is a common feature in neurodegenerative diseases and has been linked to cognitive impairment. Despite this link, the...
-
Within-Individual BOLD Signal Variability and its Implications for Task-Based Cognition: A Systematic Review
Within-individual blood oxygen level-dependent (BOLD) signal variability, intrinsic moment-to-moment signal fluctuations within a single individual...
