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Showing 1-20 of 425 results
  1. Virtual reality applications based on instrumental activities of daily living (iADLs) for cognitive intervention in older adults: a systematic review

    Background

    In recent years, the use of virtual reality (VR) as a complementary intervention in treating cognitive impairment has significantly...

    Jorge Buele, José Luis Varela-Aldás, Guillermo Palacios-Navarro in Journal of NeuroEngineering and Rehabilitation
    Article Open access 19 December 2023
  2. Amyloid-PET imaging predicts functional decline in clinically normal individuals

    Background

    There is good evidence that elevated amyloid-β (Aβ) positron emission tomography (PET) signal is associated with cognitive decline in...

    Lisa Quenon, Lyduine E. Collij, ... Bernard J. Hanseeuw in Alzheimer's Research & Therapy
    Article Open access 17 June 2024
  3. Higher FORTA (Fit fOR The Aged) scores are associated with poor functional outcomes, dementia, and mortality in older people

    Purpose

    Higher Fit fOR The Aged (FORTA) scores have been shown to be negatively associated with adverse clinical outcomes in older hospitalized...

    Farhad Pazan, Hanna Breunig, ... Martin Wehling in European Journal of Clinical Pharmacology
    Article Open access 27 September 2022
  4. The impact of near visual impairment on instrumental activities of daily living among community-dwelling older adults in Selangor

    Objective

    Near visual impairment (VI) is a common disability in an aging population. Near vision is crucial in activity of daily living including...

    Qiu Ting Kee, Mohd Harimi Abd Rahman, ... Suzana Shahar in BMC Research Notes
    Article Open access 24 October 2021
  5. Health status and associated factors of middle-aged and older adult cancer survivors in India: results from the Longitudinal Ageing Study in India

    Background

    The number of persons who have survived cancer has been increasing in India as elsewhere due to advances in detection and treatment of this...

    Aravinda Meera Guntupalli, Y. Selvamani, ... T. R. Dilip in BMC Cancer
    Article Open access 22 October 2022
  6. Health-related quality of life in subjective cognitive decline and mild cognitive impairment: a longitudinal cohort analysis

    Background

    Health-related quality of life (HR-QoL) is an important outcome for patients and crucial for demonstrating the value of new treatments....

    Sandar Aye, Vincent Bouteloup, ... Linus Jönsson in Alzheimer's Research & Therapy
    Article Open access 15 November 2023
  7. Regional cerebral tau predicts decline in everyday functioning across the Alzheimer’s disease spectrum

    Background

    Emerging difficulty performing cognitively complex everyday tasks, or ‘instrumental activities of daily living’ (IADL) may be an early...

    Mark A. Dubbelman, Kayden J. Mimmack, ... Gad A. Marshall in Alzheimer's Research & Therapy
    Article Open access 05 July 2023
  8. Characterization of symptoms and determinants of disease burden in dementia with Lewy bodies: DEvELOP design and baseline results

    Background

    The DEmEntia with LEwy bOdies Project (DEvELOP) aims to phenotype patients with dementia with Lewy bodies (DLB) and study the symptoms and...

    M. van de Beek, I. van Steenoven, ... A. W. Lemstra in Alzheimer's Research & Therapy
    Article Open access 26 February 2021
  9. Characteristics of behavioral symptoms in right-sided predominant semantic dementia and their impact on caregiver burden: a cross-sectional study

    Background

    This study aimed to clarify the neuropsychiatric symptoms of right-sided predominant semantic dementia (SD-R) by comparing them with those...

    Shunsuke Sato, Mamoru Hashimoto, ... Manabu Ikeda in Alzheimer's Research & Therapy
    Article Open access 09 October 2021
  10. Decline in cognitively complex everyday activities accelerates along the Alzheimer’s disease continuum

    Background

    Impairment in daily functioning is a clinical hallmark of dementia. Difficulties with “instrumental activities of daily living” (IADL) seem...

    Mark A. Dubbelman, Roos J. Jutten, ... Sietske A. M. Sikkes in Alzheimer's Research & Therapy
    Article Open access 29 October 2020
  11. The University of California San Diego performance-based skills assessment: a useful tool to detect mild everyday functioning difficulties in HIV-infected patients with very good immunological condition

    Everyday functioning (EF) impairment is frequent in people living with HIV (PLWH). Our aim was to better explore EF and its association with PLWH...

    Valentina Delle Donne, Nicoletta Ciccarelli, ... Simona Di Giambenedetto in Journal of NeuroVirology
    Article Open access 24 August 2020
  12. Patterns of inappropriate prescribing and clinical characteristics in patients at admission to an acute care of the elderly unit

    Purpose

    Inappropriate prescribing (IP) is common among the elderly and is associated with adverse health outcomes. The role of different patterns of...

    Mónica Zuleta, Antonio San-José, ... Carmen Pérez-Bocanegra in European Journal of Clinical Pharmacology
    Article 24 January 2024
  13. Risk factors associated with heatwave mortality in Chinese adults over 65 years

    Aging populations are susceptible to heat-related mortality because of physiological factors and comorbidities. However, the understanding of...

    Di **, Linxin Liu, ... John S. Ji in Nature Medicine
    Article 25 March 2024
  14. Comparison of Instrumental Activities of Daily Living assessment by face-to-face or telephone interviews: a randomized, crossover study

    Background

    The functional autonomy assessment is essential to manage patients with a neurodegenerative disease, but its evaluation is not always...

    Virginie Dauphinot, Nawèle Boublay, ... Pierre Krolak-Salmon in Alzheimer's Research & Therapy
    Article Open access 13 March 2020
  15. Let Us Talk Money: Subjectively Reported Financial Performance of People Living with Neurodegenerative Diseases—A Systematic Review

    Neurodegenerative diseases (NDDs) form a heterogeneous, widespread group of disorders, generally characterized by progressive cognitive decline and...

    Akke-Marij D. Ariesen, Roosa E. Tuomainen, ... Janneke Koerts in Neuropsychology Review
    Article Open access 18 August 2023
  16. Vascular dysfunction in sporadic bvFTD: white matter hyperintensity and peripheral vascular biomarkers

    Background

    Vascular dysfunction was recently reported to be involved in the pathophysiological process of neurodegenerative diseases, but its role in...

    Min Chu, Deming Jiang, ... Liyong Wu in Alzheimer's Research & Therapy
    Article Open access 05 April 2024
  17. Food security status and breast cancer screening among women in the United States: Evidence from the Health and Retirement Study and Health Care and Nutrition Study

    Purpose

    To assess the impact of food insecurity on biennial breast cancer screenings (i.e., mammography or breast X-ray) among older women in the...

    Asos Mahmood, Satish Kedia, ... Meredith Ray in Cancer Causes & Control
    Article 25 January 2023
  18. Effects of Pharmacological Treatments in Alzheimer’s Disease: Permutation Entropy-Based EEG Complexity Study

    Alzheimer’s disease (AD) is a neurodegenerative brain disease affecting cognitive and physical functioning. The currently available pharmacological...

    Ezgi Fide, Hasan Polat, ... Mehmet Siraç Özerdem in Brain Topography
    Article 18 November 2022
  19. Low incidence of advanced neurological burden but high incidence of age-related conditions that are dementia risk factors in aging people living with HIV: a data-linkage 10-year follow-up study

    Although increasing research is focusing on age-related comorbidities (ARC) among people living with HIV (PLHIV), no studies have concomitantly...

    Htein Linn Aung, Mark Bloch, ... Lucette A. Cysique in Journal of NeuroVirology
    Article Open access 12 December 2022
  20. Comparative evaluation of clinical and cerebrospinal fluid biomarker characteristics in rapidly and non-rapidly progressive Alzheimer’s disease

    Background

    Rapidly progressive forms of Alzheimer’s disease (rpAD) are increasingly recognized and may have a prevalence of up to 30% of patients...

    Janne Marieke Herden, Peter Hermann, ... Inga Zerr in Alzheimer's Research & Therapy
    Article Open access 08 June 2023
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