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High human blood meal index of mosquitoes in Arba Minch town, southwest Ethiopia: an implication for urban mosquito-borne disease transmission
Unplanned human population shifts in urban areas are expected to increase the prevalence of vector-borne diseases. This study aimed to investigate...
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Development and validation of a disulfidptosis and disulfide metabolism-related risk index for predicting prognosis in lung adenocarcinoma
BackgroundDisulfidptosis is a recently proposed novel cell death mode in which cells with high SLC7A11 expression induce disulfide stress and cell...
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A multifaceted gradient in human cerebellum of structural and functional development
The organization of the basic tissue and functional properties of the cerebellum across development is unknown. Combining several large datasets, we...
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Structural Changes in Human Brain Tissue in Prenatal Alcoholization at Different Periods of Intrauterine Development
Objectives . To assess the influences of prenatal alcoholization on the formation of various structural components of the brain in human embryos. Materi...
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Genetic insights into human cortical organization and development through genome-wide analyses of 2,347 neuroimaging phenotypes
Our understanding of the genetics of the human cerebral cortex is limited both in terms of the diversity and the anatomical granularity of brain...
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Prostate cancer survival in sub-Saharan Africa by age, stage at diagnosis, and human development index: a population-based registry study
ObjectivesTo estimate observed and relative survival of prostate cancer patients in sub-Saharan Africa (SSA) and to examine the influence of age,...
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Is there an association between COVID-19 mortality and Human development index? The case study of Nigeria and some selected countries
ObjectivesWe assessed Case Fatality Rate (CFR) of COVID-19 as an indicator to situate the performance of Nigeria relative to other selected...
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Neuroimaging Human Dopamine-Related Neurophysiology Across Development
Measures of dopamine (DA)Dopamine (DA) in vivo in humans have been obtained using positron emission tomography (PET)Positron emission tomography...
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Development of a micronucleus test using the EpiAirway™ organotypic human airway model
BackgroundThe use of organotypic human tissue models in genotoxicity has increased as an alternative to animal testing. Genotoxicity is generally...
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Comparison of structural characteristics and molecular markers of rabbit skin, pig skin, and reconstructed human epidermis for an ex vivo human skin model
The Organization for Economic Co-operation and Development approved a reconstructed human epidermis (RHE) model for in vitro skin irritation and...
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Assessment of Escherichia coli-derived Recombinant Human Bone Morphogenic Protein-2 on Fertilization and Early Embryonic Development in Rats
ObjectiveBone morphogenetic protein-2 (BMP-2) impacts fertility in women by affecting the menstrual cycle and embryonic development. We aimed to...
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Features of the Development of the Human Cerebral Cortex during the Second Trimester of Gestation
The aim of the present work was to study patterns of the postmigration development of neurons accompanying stratification of the dorsal precentral...
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Small extracellular vesicles as key players in cancer development caused by human oncogenic viruses
BackgroundExosomes are the smallest group of extracellular vesicles in size from 30 to 150 nm, surrounded by a lipid bilayer membrane, and originate...
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Identification of RIOK2 as a master regulator of human blood cell development
Anemia is a major comorbidity in aging, chronic kidney and inflammatory diseases, and hematologic malignancies. However, the transcriptomic networks...
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Reverse development of vaccines against antimicrobial-resistant pathogens
Vaccine R&D is typically a lengthy process taking >10 years. However, vaccines still fail in clinical development because of unreliable animal models...
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An artificial intelligence-based ecological index for prognostic evaluation of colorectal cancer
Background and objectiveIn the tumor microenvironment (TME), the dynamic interaction between tumor cells and immune cells plays a critical role in...
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SPRTN is involved in hepatocellular carcinoma development through the ER stress response
Endoplasmic reticulum (ER) stress, prompted by the accumulation of misfolded or unfolded proteins, triggers the activation of the unfolded protein...
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Neutrophil CD64 index as a new early predictive biomarker for infected pancreatic necrosis in acute pancreatitis
ObjectiveInfectious pancreatic necrosis (IPN) is a serious complication of acute pancreatitis, and early recognition and timely intervention are the...
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Omentin-1 inhibits the development of benign prostatic hyperplasia by attenuating local inflammation
BackgroundBenign prostatic hyperplasia (BPH) is a prevalent disease affecting elderly men, with chronic inflammation being a critical factor in its...
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The effects of glycemic index on prostate cancer progression in a xenograft mouse model
BackgroundPreviously, we found low-carbohydrate diets slowed prostate cancer (PC) growth and increased survival vs. a Western diet in mice, by...
