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Showing 1-9 of 9 results
  1. Hsa_circ_0003258 promotes prostate cancer metastasis by complexing with IGF2BP3 and sponging miR-653-5p

    Background

    More and more studies have shown that circular RNAs (circRNAs) play a critical regulatory role in many cancers. However, the potential...

    Yu-Zhong Yu, Dao-Jun Lv, ... Shan-Chao Zhao in Molecular Cancer
    Article Open access 05 January 2022
  2. Circulating circRNA as biomarkers for dilated cardiomyopathy etiology

    Abstract

    Dilated cardiomyopathy (DCM) is the third most common cause of heart failure. The multidisciplinary nature of testing — involving genetics,...

    Marina C. Costa, Maria Calderon-Dominguez, ... Rocío Toro in Journal of Molecular Medicine
    Article Open access 08 September 2021
  3. Non-coding RNAs regulating mitochondrial function in cardiovascular diseases

    Cardiovascular disease (CVD) is the leading cause of disease-related death worldwide and a significant obstacle to improving patients’ health and...

    **ang Ao, Wei Ding, ... Ying Liu in Journal of Molecular Medicine
    Article 04 April 2023
  4. The role of the methyltransferase METTL3 in prostate cancer: a potential therapeutic target

    The incidence of prostate cancer (PCa), the most prevalent malignancy, is currently at the forefront. RNA modification is a subfield of the booming...

    Xuming Zhou, Keqiang Chai, ... Guoxi Zhang in BMC Cancer
    Article Open access 02 January 2024
  5. Oncofetal protein IGF2BPs in human cancer: functions, mechanisms and therapeutic potential

    N 6 -methyladenosine (m 6 A) is the most prevalent and well-characterized internal chemical modification in eukaryotic RNA, influencing gene expression...

    Tian-Yu Zhu, Lian-Lian Hong, Zhi-Qiang Ling in Biomarker Research
    Article Open access 06 June 2023
  6. ALKBH5-mediated m6A modification of circCCDC134 facilitates cervical cancer metastasis by enhancing HIF1A transcription

    Background

    Metastasis is the main cause of mortality in cervical cancer (CC). Circular RNAs (circRNAs) have been demonstrated to play a crucial role...

    Leilei Liang, Yunshu Zhu, ... Lingying Wu in Journal of Experimental & Clinical Cancer Research
    Article Open access 26 August 2022
  7. CircXRN2 suppresses tumor progression driven by histone lactylation through activating the Hippo pathway in human bladder cancer

    Background

    Bladder cancer (BCa) is the fourth most common malignant tumor with a poor prognosis worldwide. Further exploration and research are needed...

    Bo **e, Juntao Lin, ... Feifan Wang in Molecular Cancer
    Article Open access 08 September 2023
  8. CircARID1A binds to IGF2BP3 in gastric cancer and promotes cancer proliferation by forming a circARID1A-IGF2BP3-SLC7A5 RNA–protein ternary complex

    Background

    Gastric cancer (GC) is one of the most common malignant tumors in China. Circular RNAs (circRNAs) are novel non-coding RNAs with important...

    Qiang Ma, Feifei Yang, ... Bin **ao in Journal of Experimental & Clinical Cancer Research
    Article Open access 19 August 2022
  9. CircSMARCC1 facilitates tumor progression by disrupting the crosstalk between prostate cancer cells and tumor-associated macrophages via miR-1322/CCL20/CCR6 signaling

    Background

    Circular RNAs (circRNAs) mediate the infiltration of tumor-associated macrophages (TAMs) to facilitate carcinogenesis and development of...

    Tao **e, Du-jiang Fu, ... Shan-Chao Zhao in Molecular Cancer
    Article Open access 01 September 2022
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