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Impact of hormonal contraception on endometrial histology in patients with Lynch syndrome, a retrospective pilot study
Hormonal contraception (HC) is a well-recognized protection against endometrial cancer (EC) in the general population. It has not been established if...
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Hormonal contraceptive use among women living with hypertension in sub-Saharan Africa: insights from 12 countries
ObjectivesGiven the well-established link between hormonal contraceptives and hypertension risk, and the paucity of research on hormonal...
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Beyond the pill: contraception and the prevention of hereditary ovarian cancer
BRCA1 and BRCA2 mutation carriers face an elevated lifetime risk of develo** ovarian cancer. Oral contraceptives have been shown to significantly...
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Clinical features of migraine with onset prior to or during start of combined hormonal contraception: a prospective cohort study
Many studies have described the features of menstrually related migraines but there is a lack of knowledge regarding the features of migraine in...
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Gender Differences in Cardiovascular Health: Hormonal Effects on Cardiovascular Risk and Management
Cardiovascular disease is the number one cause of death worldwide both in men and women. Significant differences however exist in the age of onset,...
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Assessment of the Effects of Abrocitinib on the Pharmacokinetics of Probe Substrates of Cytochrome P450 1A2, 2B6 and 2C19 Enzymes and Hormonal Oral Contraceptives in Healthy Individuals
Background and ObjectiveAbrocitinib is an oral small-molecule Janus kinase (JAK)-1 inhibitor approved for the treatment of moderate-to-severe atopic...
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The Relationship between the Premenstrual Syndrome and Resting Cardiac Vagal Tone in Young Healthy Females: Role of Hormonal Contraception
Evolutionary-based predictions imply that the premenstrual syndrome (PMS) affects women who failed to conceive while in biosocial conditions that...
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Blood oxidative stress biomarkers in women: influence of oral contraception, exercise, and N-acetylcysteine
PurposeTo compare physiological responses to submaximal cycling and sprint cycling performance in women using oral contraceptives (WomenOC) and...
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Progesterone from ovulatory menstrual cycles is an important cause of breast cancer
Many factors, including reproductive hormones, have been linked to a woman’s risk of develo** breast cancer (BC). We reviewed the literature...
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The effect of the menstrual cycle and hyperglycaemia on hormonal and metabolic responses during exercise
PurposeVariations in substrate metabolism have been identified in women during continuous steady-state aerobic exercise performed at the same...
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Modifiable risk factors in women at high risk of breast cancer: a systematic review
BackgroundModifiable risk factors (alcohol, smoking, obesity, hormone use, and physical activity) affect a woman’s breast cancer (BC) risk. Whether...
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Pharmaceutical and Pharmacological Evaluation of the Effect of Nano-Formulated Spironolactone and Progesterone on Inflammation and Hormonal Levels for Managing Hirsutism Experimentally Induced in Rats
Hirsutism is a dermatological condition that refers to the excessive growth of hair in androgen-sensitive areas in women. Recently, the enhancement...
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Relationship of Breast Cancer with Other Hormone-Sensitive Cancers
Women are diagnosed with breast cancer (BC) on a global basis every year, making it the most prevalent kind of cancer in women. A link between BC and...
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Sex Hormones: Hormonal Contraception and Hormone Replacement Therapy
The most important sex hormones are the ER agonist estradiol, the gestagen progesterone, and the androgen 5α-dihydrotestosterone. Estradiol is...
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Biomaterials and Contraception: Promises and Pitfalls
The present state of reproductive and sexual health around the world reveals disparities in contraceptive use and effectiveness. Unintended pregnancy...
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The Impacts of Sex Differences and Sex Hormones on Fear Extinction
Fear extinction memories are strongly modulated by sex and hormonal status, but the exact mechanisms are still being discovered. In humans, there are...
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Ostarine blunts the effect of endurance training on submaximal endurance in rats
The purpose of this study is to study the effects of ostarine alone and in combination with endurance training in sexually mature, male Wistar rats....
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Exogenous hormone therapy and non-melanoma skin cancer (keratinocyte carcinoma) risk in women: a systematic review and meta-analysis
Previous studies reported inconsistent results regarding the association between keratinocyte carcinoma (KC) and exogenous hormone therapy. This...
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Economic Evidence for Pharmacist Prescribing in Community Pharmacy
The effectiveness of pharmacist interventions is supported by high-level evidence from around the world. Such effectiveness combined with high levels...