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Association between high cardiac output at altitude and acute mountain sickness: preliminary study on Mt. Fuji
BackgroundAcute mountain sickness (AMS) affects around 30% of people climbing Mt. Fuji, but its pathogenesis is incompletely understood. The...
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Current Problems in Diagnosis and Treatment of High-Altitude Sickness
Acute high-altitude sickness includes various symptoms and pathology that a non-acclimatized individual experiences while travelling to higher...
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Antioxidant Therapy for High Altitude Sickness and Nano-Medicine
High altitude sickness is associated with increased levels of reactive oxygen species (ROS) that leads to oxidative stress in cells. At elevated...
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High Altitude Sickness: Environmental Stressor and Altered Physiological Response
By the end of the nineteenth century, humans have been fascinated by and drawn to mountains and mostly peaks had been climbed by numerous...
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Role of Genomics, Proteomics, and Antioxidant Interventions in Preventing High Altitude Sickness
Some individuals become sick on spending some time at low atmospheric pressure which is above 1500 m (5000 feet), i.e. flying in a plane or climbing...
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High Altitude Sickness and Antioxidant Interventions
High altitude sickness (HAS) has been one of the important environmental challenges occurring as a result of the failure of the physiological...
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High Altitude Sickness – Solutions from Genomics, Proteomics and Antioxidant Interventions
This book reviews the recent advances in the development of proteomics-based biomarkers for the non-invasive diagnosis of altitude sickness and...
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High Arterial Oxygen Saturation in the Acclimatized Lowlanders Living at High Altitude
Blood oxygen saturation (SpO 2 ) is a key indicator of oxygen availability in the body. It is known that a low SpO 2 at high altitude is associated with...
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Expression of Vascular Endothelial Growth Factor at High Altitude
Oxygen plays an important role in aerobic respiration in mammals. However, there is subsequent decrease in partial pressure of oxygen with increase...
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Introduction to High Altitude and Hypoxia
Climbing to a high altitude causes breathing to shorten, which reduces the amount of oxygen in the tissues and causes hypoxia. High altitude sickness...
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Longitudinal multi-omics analysis uncovers the altered landscape of gut microbiota and plasma metabolome in response to high altitude
BackgroundGut microbiota is significantly influenced by altitude. However, the dynamics of gut microbiota in relation to altitude remains undisclosed.
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Hypoxia-Inducible Factor Activation in High-Altitude Stress
As altitude increases, the tropospheric barometric pressure falls. A proportionate fall in the partial pressure of oxygen happens along with a...
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Decompression strain in parachute jumpmasters during simulated high-altitude missions: a special reference to preoxygenation strategies
PurposeMilitary parachute operations are often executed at high altitude, from an unpressurized aircraft compartment. Parachute jumpmasters (JM) are...
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Changes in expression levels of erythrocyte and immune-related genes are associated with high altitude polycythemia
BackgroundAs a chronic mountain sickness(CMS) with the highest incidence and the greatest harm, the pathogenesis of high altitude polycythemia (HAPC)...
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Superoxide dismutase 1-modified dental pulp stem cells alleviate high-altitude pulmonary edema by inhibiting oxidative stress through the Nrf2/HO-1 pathway
High-altitude pulmonary edema (HAPE) is a deadly form of altitude sickness, and there is no effective treatment for HAPE. Dental pulp stem cells...
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Mechanism of Skeletal Muscle Atrophy at High Altitude: Role of Herbals and Nutraceuticals
Exposure to high altitude leads to numerous adaptive and maladaptive responses in our body which accentuates a decline in the physical performance....
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Hypoxia Conditioning for High-Altitude Pre-acclimatization
PurposeMain purposes of pre-acclimatization by hypoxia conditioning (HC) are the prevention of high-altitude illnesses and maintenance of aerobic...
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High-altitude decompression strain can be reduced by an early excursion to moderate altitude while breathing oxygen
Recent observations suggest that development of venous gas emboli (VGE) during high-altitude flying whilst breathing hyperoxic gas will be reduced by...
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Altitude Acclimatization Via Pharmacological and Non-pharmacological Interventions
The key element of hypobaric hypoxia is declined barometric pressure and lower partial pressure at high altitudes. Hypobaric hypoxia at high...
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Leaky Gut at High Altitude: Synbiotics May Be a Possible Solution
Sojourn to high altitude may lead to gastrointestinal (GI) discomfort due to acute hypoxia. GI discomfort is one of the problems observed in people...