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Hepatitis B virus reactivation in seronegative occult hepatitis B patient receiving ibrutinib therapy
BackgroundIbrutinib is a Bruton’s tyrosine kinase (BTK) inhibitor approved for the treatment for several mature B-cell malignancies. Reactivation of...
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Understanding lactate in the development of Hepatitis B virus-related hepatocellular carcinoma
Hepatitis B Virus (HBV) is a hepatotropic virus that can establish a persistent and chronic infection in humans. Chronic hepatitis B (CHB) infection...
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Hepatitis E Virus
Since the sequence of hepatitis E virus (HEV) was determined from a patient with enterically transmitted non-A, non-B hepatitis in 1989, similar...
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Nanoscale Vaccines for the Prevention of Hepatitis B Virus Infection
Hepatitis B is a global life-threatening viral infection associated with a high risk of death resulting from chronic liver cirrhosis and liver...
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Significance of hepatitis B virus capsid dephosphorylation via polymerase
BackgroundIt is generally believed that hepatitis B virus (HBV) core protein (HBc) dephosphorylation (de-P) is important for viral DNA synthesis and...
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Path to Cure Hepatitis B: How Far Are We?
Hepatitis B infection is caused by the hepatitis B virus (HBV), which damages the liver and can lead to chronic liver diseases such as cirrhosis and...
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Characterization of a breakthrough vaccine escape strain associated with overt hepatitis B virus infection
Hepatitis B virus (HBV) vaccine is composed of the purified hepatitis B surface antigen (HBsAg) that is produced by recombinant DNA technology. The...
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Hepatitis E Virus Zoonotic Axis
Viral hepatitis is primarily caused by five unrelated hepatotropic viruses, hepatitis A, B, C, D, and E. While hepatitis A through C are commonly...
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Puzzles for Hepatitis E Virus
Hepatitis E virus (HEV) is an important but understudied virus that has been the major cause of acute viral hepatitis worldwide. In recent decades,...
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Correlation analysis of hepatic steatosis and hepatitis B virus: a cross-sectional study
BackgroundThe co-occurrence of chronic hepatitis B (CHB) and metabolic dysfunction-associated fatty liver disease (MAFLD) has drawn considerable...
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miR-3188 inhibits hepatitis B virus transcription by targeting Bcl-2
Transcription of the covalently closed circular DNA (cccDNA) of hepatitis B virus (HBV) is subject to dual regulation by host factors and viral...
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Reactivation of occult hepatitis B virus infection in a renal transplant recipient
We report a case of hepatitis B virus (HBV) reactivation in a renal transplant recipient. Reactivation manifested as an occult infection with...
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Characteristics of Hepatitis B virus integration and mechanism of inducing chromosome translocation
Hepatitis B virus (HBV) integration is closely associated with the onset and progression of tumors. This study utilized the DNA of 27 liver cancer...
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Transmission of Hepatitis E Virus
Transmission of hepatitis E virus (HEV) occurs predominantly by the fecal–oral route. Large epidemics of hepatitis E in the develo** countries of...
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Characterization of mutations in hepatitis B virus DNA isolated from Japanese HBsAg-positive blood donors in 2021 and 2022
Missense mutations in certain small envelope proteins diminish the efficacy of antibodies. Consequently, tracking the incidence and types of...
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A cross-sectional survey of hepatitis B virus screening in patients who received immunosuppressive therapy for rheumatoid arthritis in Japan
BackgroundPatients with a history of hepatitis B virus (HBV) infection who are receiving immunosuppressive therapy are at risk of HBV reactivation...
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Impact of preoperative antiviral therapy on the prognosis of hepatitis B virus-related hepatocellular carcinoma
BackgroundFor chronic hepatitis B virus (HBV) infection patients, increasing evidence has demonstrated the effectiveness of expanding the indications...
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SUV39H1 is a novel biomarker targeting oxidative phosphorylation in hepatitis B virus-associated hepatocellular carcinoma
BackgroundAs a histone methyltransferase, suppressor of variegation 3–9 homolog 1 (SUV39H1) plays an important role in the occurrence and development...
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Morphogenesis of Hepatitis E Virus
Hepatitis E virus, a leading cause of acute hepatitis worldwide, has been recognized as non-enveloped virus since its discovery in the 1980s....
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The Influence of ESR2 Gene Polymorphisms on Susceptibility to Hepatitis B Virus-Related Chronic Hepatitis, Liver Cirrhosis, and Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) represents an estrogen-dependent tumor. The action of estrogen is regulated via estrogen receptor (ER). Polymorphisms...
