Search
Search Results
-
-
An Hsp70 promoter–based mouse for heat shock–induced gene modulation
AbstractPhysical therapy is extensively employed in clinical settings. Nevertheless, the absence of suitable animal models has resulted in an...
-
The beauty and complexity of the small heat shock proteins: a report on the proceedings of the fourth workshop on small heat shock proteins
The Fourth Cell Stress Society International workshop on small heat shock proteins (sHSPs), a follow-up to successful workshops held in 2014, 2016...
-
Inflammation, coagulation, and cellular injury in heat-induced shock
BackgroundThe number of heatstroke victims hit record numbers in 2022 as global warming continues. In heat-induced injuries, circulatory shock is the...
-
Kainic Acid-Induced Excitotoxicity Leads to the Activation of Heat Shock Response
Heat shock response (HSR) which is regulated by heat shock factor 1 (HSF1) is the most important mechanism and the major regulator that prevents...
-
Heat Shock Proteins in Cancer Immunotherapy
Background Immunotherapy-based treatment approaches have demonstrated promising results in cancer patients. However, the efficacy of...
-
Nutri-stress, mitochondrial dysfunction, and insulin resistance—role of heat shock proteins
Excess nutrient flux into the cellular energy system results in a scenario of cellular metabolic stress in diseases involving insulin resistance,...
-
Identification and expression analysis of heat shock protein family genes of gall fly (Procecidochares utilis) under temperature stress
Heat shock proteins (HSP) are molecular chaperones involved in many normal cellular processes and environmental stresses. At the genome-wide level,...
-
Novel Strategy for In Vitro Validation of Babesia orientalis Heat Shock Proteins Chaperone Activity and Thermostability
BackgroundBabesia orientalis is an intra-erythrocytic protozoan parasite that causes babesiosis in water buffalo. The genome of B. orientalis has...
-
Elevation of major constitutive heat shock proteins is heat shock factor independent and essential for establishment and growth of Lgl loss and Yorkie gain-mediated tumors in Drosophila
Cancer cells generally overexpress heat shock proteins (Hsps), the major components of cellular stress response, to overcome and survive the diverse...
-
New Zealand blackcurrant extract modulates the heat shock response in men during exercise in hot ambient conditions
PurposeTo determine if 7d of New Zealand blackcurrant (NZBC) extract alters the heat shock, inflammatory and apoptotic response during prolonged...
-
Features of Changes in Exogenous Heat Shock Proteins (HSP 27 and HSP 70) in Patients with Occupational Nervous System Pathologies
Abstract —The aim of this study was to identify and compare changes in serum concentrations of heat shock proteins (HSP 27 and HSP 70) in patients...
-
Linking Heat Shock Protein 70 and Parkin in Parkinson’s Disease
Parkinson’s disease (PD) is a neurodegenerative disease that affects millions of elderly people worldwide and is characterized by the progressive...
-
Association between Polymorphisms of Heat Shock Protein HSPA5 and Risk of Type 2 Diabetes Mellitus
We studied the relationship between the HSPA5 gene polymorphisms and the risk of type 2 diabetes mellitus. Genoty** of three SNPs of the HSPA5 gene...
-
Heat Shock Proteins as Emerging Therapeutic and Vaccine Targets Against Leishmaniasis
Leishmania, an intracellular protozoa parasite, is the causative agent of a group of diseases called leishmaniasis. Clinical manifestations of...
-
The deubiquitinase USP40 preserves endothelial integrity by targeting the heat shock protein HSP90β
Endothelial cell (EC) barrier disruption and inflammation are the pathological hallmarks of vascular disorders and acute infectious diseases and...
-
Effects of resistance training on heat shock response (HSR), HSP70 expression, oxidative stress, inflammation, and metabolism in middle-aged people
Resistance training (RT) can increase the heat shock response (HSR) in the elderly. As middle-aged subjects already suffer physiological declines...
-
Heat Shock Proteins of Malaria
This new edition describes the role of heat shock proteins in the life cycle of malaria parasites, particularly in the context of intracellular...
-
Heat Shock Proteins in Tumor Immunology
Background Heat shock proteins (HSPs) are molecular chaperones, which support tumorigenesis by sustaining various hallmarks of cancer. It is now well...
-
Heat shock protein 27 in the pathogenesis of COVID-19 and non-COVID acute respiratory distress syndrome
Acute respiratory distress syndrome (ARDS) is a common cause of hypoxemic respiratory failure in intensive care units that has increased dramatically...
