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Type IIx muscle fibers are related to poor body composition, glycemic and lipidemic blood profiles in young females: the protective role of type I and IIa muscle fibers
PurposeThe aim of the present study was to investigate the association between muscle fiber composition, body composition, resting glycemic–lipidemic...
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Contribution of Elastic and Collagen Fibers to the Mechanical Behavior of Bovine Nuchal Ligament
Ligamentum nuchae is a highly elastic tissue commonly used to study the structure and mechanics of elastin. This study combines imaging, mechanical...
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Regeneration of Skeletal Muscle Fibers and Regulation of Myosatellitocytes Metabolism
AbstractSkeletal muscles are heterogeneous tissue containing different types of muscle fibers. Their distribution depends on heredity, type of...
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Spatial Distribution of Parvalbumin-Positive Fibers in the Mouse Brain and Their Alterations in Mouse Models of Temporal Lobe Epilepsy and Parkinson’s Disease
Parvalbumin interneurons belong to the major types of GABAergic interneurons. Although the distribution and pathological alterations of parvalbumin...
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Zero Gravity is a Factor that Induces Negative Changes in Myelinated Fibers of the Spinal Tracts
The development of hypogravitational motor syndrome is an essential negative consequence of weightlessness for humans; an important role in the...
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Finite element analysis of the influence of interdigitation pattern and collagen fibers on the mechanical behavior of the midpalatal suture
The midpalatal suture (MPS) corresponds to the tissue that joins the two maxillary bones. Understanding the mechanical behavior of this tissue is of...
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Ex Vivo Human Single Muscle Fibers: An Insightful Approach to Skeletal Muscle Function
Skeletal muscle, a highly heterogeneous tissue, is composed of a variety of cells and different muscle fiber types, mostly classified as slow and...
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Remodeling the Architecture of Collagen-Containing Connective Tissue Fibers of Metastatic Prostate Cancer
The morphological study was aimed at determining the role of fibrillar organization of the collagen-containing connective tissue of prostate cancer...
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Climbing fibers provide essential instructive signals for associative learning
Supervised learning depends on instructive signals that shape the output of neural circuits to support learned changes in behavior. Climbing fiber...
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Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials
Although targeting oxidative phosphorylation (OXPHOS) is a rational anticancer strategy, clinical benefit with OXPHOS inhibitors has yet to be...
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Novel characteristics of soluble fibrin: hypercoagulability and acceleration of blood sedimentation rate mediated by its generation of erythrocyte-linked fibers
Soluble fibrin (SF) in blood consists of monomers lacking both fibrinopeptides A with a minor population in multimeric clusters. It is a substantial...
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Surgical Strategy for Low-Grade Gliomas Arising from Short Arcuate Fibers
The general understanding is that low-grade gliomas are by nature ‘diffuse’, ‘invasive’ or ‘infiltrating’ into the normal brain parenchyma....
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Probing the multimodal fungiform papilla: complex peripheral nerve endings of chorda tympani taste and mechanosensitive fibers before and after Hedgehog pathway inhibition
The fungiform papilla (FP) is a gustatory and somatosensory structure incorporating chorda tympani (CT) nerve fibers that innervate taste buds (TB)...
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Cerebral White Matter Alterations Associated With Oligodendrocyte Vulnerability in Organic Acidurias: Insights in Glutaric Aciduria Type I
The white matter is an important constituent of the central nervous system, containing axons, oligodendrocytes, and its progenitor cells, astrocytes,...
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Type I collagen and fibromodulin enhance the tenogenic phenotype of hASCs and their potential for tendon regeneration
Our previous work demonstrated the tendon-derived extracellular matrix (ECM) extracts as vital niches to specifically direct mesenchymal stem cells...
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NLRP3 inflammasome up-regulates major histocompatibility complex class I expression and promotes inflammatory infiltration in polymyositis
ObjectiveThis study was designed to investigate the role of the nucleotide-binding-domain -and leucine-rich repeat -containing (NLR) family,...
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Long-Term Course of Circulating Elastin, Collagen Type I, and Collagen Type III in Patients with Spontaneous Cervical Artery Dissection: a Prospective Multicenter Study
An impaired integrity of vascular elements and the extracellular matrix (ECM) has been discussed to play a critical role in the pathophysiology of...
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Plasmodium vivax tryptophan-rich antigen reduces type I collagen secretion via the NF-κBp65 pathway in splenic fibroblasts
BackgroundThe spleen plays a critical role in the immune response against malaria parasite infection, where splenic fibroblasts (SFs) are abundantly...
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Biliary drainage combined with simultaneous 125I seed strand brachytherapy for the treatment of hilar cholangiocarcinoma
BackgroundTo evaluate the clinical efficacy of percutaneous biliary drainage (PBD) combined with 125 I seed strand brachytherapy (ISSB) for the...
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Skeletal muscle fiber hypercontraction induced by Bothrops asper myotoxic phospholipases A2 ex vivo does not involve a direct action on the contractile apparatus
Myonecrosis is a frequent clinical manifestation of envenomings by Viperidae snakes, mainly caused by the toxic actions of secreted phospholipase A 2 ...
