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Genetic basis and spatial distribution of glucose-6-phosphate dehydrogenase deficiency in ecuadorian ethnic groups: a malaria perspective
BackgroundGlucose-6-phosphate dehydrogenase deficiency (G6PDd) is an X-linked disorder affecting over 400 million people worldwide. Individuals with...
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Genetic diversity and natural selection of Plasmodium vivax reticulocyte invasion genes in Ecuador
BackgroundKnowledge of the diversity of invasion ligands in malaria parasites in endemic regions is essential to understand how natural selection...
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Clinical, genomics and networking analyses of a high-altitude native American Ecuadorian patient with congenital insensitivity to pain with anhidrosis: a case report
BackgroundCongenital insensitivity to pain with anhidrosis (CIPA) is an extremely rare autosomal recessive disorder characterized by insensitivity to...
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Genotypes and phenotypes of resistance in Ecuadorian Plasmodium falciparum
BackgroundMalaria continues to be endemic in the coast and Amazon regions of Ecuador. Clarifying current Plasmodium falciparum resistance in the...
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Clinical, cytogenetic, and genomic analyses of an Ecuadorian subject with Klinefelter syndrome, recessive hemophilia A, and 1;19 chromosomal translocation: a case report
BackgroundHemophilia A is considered one of the most common severe hereditary disorders. It is an X-linked recessive disease caused by a deficiency...
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History of Rabies in Ecuador
Different mammals have been present in the Ecuadorian pre-Columbian territories for millennia. Today, they are still represented in vessels used in... -
Under pressure: phenotypic divergence and convergence associated with microhabitat adaptations in Triatominae
BackgroundTriatomine bugs, the vectors of Chagas disease, associate with vertebrate hosts in highly diverse ecotopes. It has been proposed that...
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Compliance with antibiotic prophylaxis guidelines in caesarean delivery: a retrospective, drug utilization study (indication-prescription type) at an Ecuadorian hospital
BackgroundPreoperative antibiotic prophylaxis is essential for preventing surgical site infection (SSI). The aim of this study was to evaluate...
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A prospective seroepidemiological study of toxocariasis during early childhood in coastal Ecuador: potential for congenital transmission and risk factors for infection
BackgroundAlthough Toxocara spp. infection has a worldwide distribution, to our knowledge, no data from birth cohorts have been reported in...
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“It Isn’t Going to Reach Here”: Venezuelan Equine Encephalitis in Texas, 1971
Venezuelan equine encephalitis virus (VEEV)-I AB is a mosquito-borne arbovirus first recognized in Venezuela in 1938. An outbreak of this virus was... -
In conversation with Diego Bohórquez
As Nature Neuroscience celebrates its 25th anniversary, we are having conversations with both established leaders in the field and those earlier in...
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Amphimerus lancea as a Potential Etiological Agent of Human Amphimerosis in South America: A Morphological Analysis Based on Literature Data
PurposeDespite recent advances in the study of amphimerosis, aspects related to the taxonomy of the opisthorchiid species involved in human infection...
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Anopheline and human drivers of malaria risk in northern coastal, Ecuador: a pilot study
BackgroundUnderstanding local anopheline vector species and their bionomic traits, as well as related human factors, can help combat gaps in...
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Human genetics and genomics research in Ecuador: historical survey, current state, and future directions
BackgroundIn South America, the history of human genetics is extensive and its beginnings go back to the onset of the twentieth century. In Ecuador,...
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Exotic ticks removed from German travelers
We report the finding of five nymphs and three adult ticks attached to German tourists while traveling the American continents. All eight specimens...
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Active Transmission of Trypanosoma cruzi in Schoolchildren from the Amazon Region in Napo Province, Ecuador
PurposeChagas disease, caused by the protozoan parasite Trypanosoma cruzi , is a vector-borne disease with a major disease burden in the Americas,...
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Necrotising pneumonia caused by Curvularia hawaiiensis (syn. Bipolaris hawaiiensis) and Mycobacterium tuberculosis coinfection in a patient with ascariasis: a case report and review
IntroductionCurvularia hawaiiensis (formerly Bipolaris hawaiiensis ) is a plant pathogen often isolated from soil and vegetative material. However,...
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Cognitive Dysfunction in COVID-19
We present here an analysis of non-Russian publications illustrating changes in concepts relating to the etiology, pathogenesis, main...
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Clinical, cytogenetic, and molecular findings in a patient with ring chromosome 4: case report and literature review
BackgroundSince 1969, 49 cases have been presented on ring chromosome 4. All of these cases have been characterized for the loss of genetic material....
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Diverse origin of Plasmodium falciparum in northwest Ecuador
BackgroundEcuador plans to eliminate malaria by 2020, and the country has already seen a decrease in the number of cases from more than 100,000 in...