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Lipid droplets in pathogen infection and host immunity
As the hub of cellular lipid metabolism, lipid droplets (LDs) have been linked to a variety of biological processes. During pathogen infection, the...
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Proteomics in the Study of Host-Pathogen Interactions
DNA is referred to as the basic blueprint of life, but the implementation of the genetic plan is carried out by the activities of proteins. Hence,...
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The Role of Host and Fungal Factors in the Commensal-to-Pathogen Transition of Candida albicans
Abstract Purpose of ReviewThe fungus Candida albicans has evolved to live in close association with warm-blooded hosts and is found frequently on...
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Pathogen–Host Interaction and Its Associated Molecular Mechanism in HFMD Pathology and Immunology
Hand, foot, and mouth disease (HFMD) is caused by the enterovirus family, which includes EV-A71 and more than 10 other members. The disease involves...
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Deciphering the Role of Epigenetic Reprogramming in Host-Pathogen Interactions
The success of a pathogen within the host depends on various extrinsic factors that work in a synergistic mechanism to promote pathogenesis. One such...
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Host–Microbe Interactions and Infectious Disease
Infectious disease is defined as the damage that occurs in a host because of a host–microbe interaction, where damage is the disruption of the normal...
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Hypoxia-inducible factor-driven glycolytic adaptations in host-microbe interactions
Mammalian cells utilize glucose as a primary carbon source to produce energy for most cellular functions. However, the bioenergetic homeostasis of...
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Metabolomics: A Promising Tool to Study Disease Biomarkers and Host-Pathogen Interactions
Metabolomics is a comprehensive analysis of small-molecule metabolite profiles of cellular processes using mass spectrometry combined with advanced...
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Evolution of Pathogenicity and Virulence
Evolutionary biologists define virulence as reduction in host fitness (survival and reproduction) caused by pathogens. The avirulence hypothesis...
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Implications of bacteria–bacteria interactions within the plant microbiota for plant health and productivity
Crop production currently relies on the widespread use of agrochemicals to ensure food security. This practice is considered unsustainable, yet has...
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Multifaceted roles of flavonoids mediating plant-microbe interactions
Plant-microbe interactions dynamically affect plant growth, health, and development. The mechanisms underpinning these associations are—to a large...
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Galectins in Host–Pathogen Interactions: Structural, Functional and Evolutionary Aspects
Galectins are a family of ß-galactoside-binding lectins characterized by a unique sequence motif in the carbohydrate recognition domain, and...
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Microfluidic PCR and network analysis reveals complex tick-borne pathogen interactions in the tropics
BackgroundIxodid ticks, particularly Rhipicephalus sanguineus s.l., are important vectors of various disease-causing agents in dogs and humans in...
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Progress in mass spectrometry approaches to profiling protein–protein interactions in the studies of the innate immune system
Understanding protein–protein interactions (PPIs) is pivotal for deciphering the intricacies of biological processes. Dysregulation of PPIs underlies...
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Sequential host-bacteria and bacteria-bacteria interactions determine the microbiome establishment of Nematostella vectensis
BackgroundThe microbiota of multicellular organisms undergoes considerable changes during host ontogeny but the general mechanisms that control...
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Managing host-parasite interactions in humans and wildlife in times of global change
Global change in the Anthropocene has modified the environment of almost any species on earth, be it through climate change, habitat modifications,...
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Interactions between Leishmania parasite and sandfly: a review
Leishmaniasis transmission cycles are maintained and sustained in nature by the complex crosstalk of the Leishmania parasite, sandfly vector, and the...
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Local Onco-Sphere: Tumor–Immune Cells Interactions
In the local onco-sphere, tumor cells are constantly communicating with their surrounding environment, including immune cells, stromal cells and...
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Siglecs at the Host–Pathogen Interface
Siglecs are sialic acid (Sia) recognizing immunoglobulin-like receptors expressed on the surface of all the major leukocyte lineages in mammals....
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Time-resolved transcriptional profiling of Trichinella-infected murine myocytes helps to elucidate host–pathogen interactions in the muscle stage
BackgroundParasites of the genus Trichinella are the pathogenic agents of trichinellosis, which is a widespread and severe foodborne parasitic...
