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Systematic review of genotoxicity induced by occupational exposure to antineoplastic drugs
With increasing numbers of cancer cases, the use of antineoplastic agents is expected to rise. This will be accompanied by an increase in...
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Drugs Affecting Gastrointestinal Functions
The digestive system in humans is the mechanism that the body uses to carry out digestion. Food is ingested by the digestive system, which is...
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Natural Products as Nano-Antidiabetic Drugs
Natural products have emerged as promising candidates for the development of nano-antidiabetic drugs, presenting a novel approach to combat the...
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Chronology of Anticancer Drugs and Their Development
Chemotherapeutic drugs, or anticancer, are the chemical components which are used to treat cancer. The term anticancer drugs evolved in the era of...
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Anti-inflammatory drugs prevent memory and hippocampal plasticity deficits following initial binge-like alcohol exposure in adolescent male rats
RationaleBinge drinking during adolescence impairs learning and memory on the long term, and many studies suggest a role of neuroinflammation....
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Foreign Compounds: Foods, Drugs, Chemicals, and Lifestyles
Foods are substances that contain essential nutrients such as proteins, carbohydrates...
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Cardiotoxicity of HER2-Targeted Drugs When Combined with Other Drugs: A Systematic and Meta-analysis of Randomized Controlled Trials
The development and use of HER2-targeted drugs has improved the prognosis of HER2-positive cancer patients. However, in addition to improved survival...
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Advanced Drug Delivery Strategies for Metal-Based Anticancer Drugs
Metal-based anticancer drugs, such as platinum complexes (e.g., cisplatin, carboplatin, and oxaliplatin), have demonstrated remarkable efficacy in...
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Within-subject pharmacokinetic variability has a strong influence on individual exposure ratios in bioequivalence studies, hence on drug formulation interchangeability
IntroductionBioequivalence between a reference and a generic drug is based on the hypothesis that a ± 20% change in blood exposure (or ± 10% for...
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New Antifungal Drugs: Discovery and Therapeutic Potential
There has been an increase in invasive fungal infections, which are a universal problem due to the longer average lifespan, the number of...
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Chronology of Anticancer Drugs and Their Development
Chemotherapeutic drugs, or anticancer, are the chemical components which are used to treat cancer. The term anticancer drugs evolved in the era of...
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RETRACTED ARTICLE: Impact of Prenatal Acetaminophen Exposure for Hippocampal Development Disorder on Mice
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used as analgesic agents. They have been detected in various environmental matrices. The...
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New Anti-tuberculous Drugs: Bedaquiline, Delamanid, and Pretomanid
Development of new drugs to treat drug-resistant tuberculosis is most important in the fight against the global spread of this contagious and...
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Fentanyl Exposure and Detection Strategies Utilized by Clinical Trial Participants Seeking Linkage to Opioid Use Disorder Treatment at a Syringe Service Program
IntroductionThe USA continues to face a fentanyl-driven overdose epidemic. Prior research has demonstrated users of illicit opioids are concerned...
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Drugs of Abuse: Trends and Advanced Analytical Methods
Abuse of drugs is correlated with various medical, behavioral, psychological, spiritual, financial, social, family, and legal concerns and profoundly...
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Drugs Used for Immunomodulation
Immunomodulators are substances that can modify the body’s immune response. The human immune system comprises a variety of components, including...
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Drugs from Nature: Targets, Assay Systems, and Leads
The overview is done to determine whether the era of natural products for drug discovery is over or not over. Though the drug discovery process is...
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Time-Dependent Pharmacokinetics of Immune Checkpoint Inhibitors and their Implications and Considerations for Exposure–Response Analysis
PurposeThe purpose of this review is to provide a comprehensive summary of recent studies characterizing the pharmacokinetics of newly approved...
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The pipeline for drugs for control and elimination of neglected tropical diseases: 1. Anti-infective drugs for regulatory registration
The World Health Organization ‘Ending the neglect to attain the Sustainable Development Goals: A road map for neglected tropical diseases 2021–2030’...
