Search
Search Results
-
Biomarkers for Huntington's Disease Improving Clinical Outcomes
Huntington’s disease (HD) is a fatal, inherited, neurodegenerative disorder, characterized by chorea, motor instabilities, psychiatric manifestations...
-
Biomarkers for Alzheimer’s Disease
Alzheimer’s disease is a neurodegenerative disease, which affects intellectually is frequently observed in elderly generations and genetically linked...
-
Biomarkers for Alzheimer’s Disease Drug Development
This fully updated volume provides an up-to-date and comprehensive overview of the current state of technologies hel** to accelerate Alzheimer’s...
-
Cerebrospinal Fluid Biomarkers in Huntington’s Disease
Huntington’s disease (HD) is a devastating neurodegenerative disorder caused by a CAG repeat expansion mutation in the HTT gene that leads to...
-
Fluid-Based Biomarkers of Alzheimer’s Disease
Alzheimer’s disease (AD) is the most common type of dementia, whose incidence is expected to increase drastically due to population aging. The early...
-
The Utility of Biomarkers for Huntington’s Disease
Huntington’s disease (HD) is a fatal, genetic, neurodegenerative disorder, characterized by chorea, other motor instabilities, psychiatric...
-
Mitochondrial/Oxidative Stress Biomarkers in Huntington’s Disease
Huntington’s disease (HD) is a hereditary neurodegeneration caused by a mutation in the HTT gene, leading to mutated huntingtin protein aggregation....
-
Biomarkers in Huntington’s Disease
Huntington’s disease (HD) is a neurodegenerative disorder caused by a trinucleotide repeat expansion mutation. The expansion length is the diagnostic...
-
Microbiome and Metabolomic Biomarkers for Huntington’s Disease
Huntington’s disease (HD) is a fatal monogenic neurodegenerative disorder caused by the expansion of the trinucleotide tandem repeat in the...
-
Optimized Pre-analytical Handling Protocol for Blood-Based Biomarkers of Alzheimer’s Disease
The therapeutic management of patients with Alzheimer’s disease (AD) has been hindered by poor diagnostic accuracy. As such, there is an unmet...
-
Biomarkers in Parkinson’s Disease
Parkinson’s disease (PD) is the second most common neurodegenerative disorder, with a documented significant increase in its prevalence in the past...
-
Recommended Resources for Biomarkers in Disease: Toxicology
It is extremely challenging to assess patients exposed to toxins. An accurate history is difficult to obtain; thus, tools and platforms for...
-
MicroRNAs as Potential Biomarkers in Huntington’s Disease
MicroRNAs (miRNAs) play an essential role in many physiological processes of our body. Dysregulation of miRNAs is involved in the pathology of...
-
Retinal Imaging and Functional Biomarkers of Huntington’s Disease
The retina shares a common embryological origin with the brain and both organs have numerous anatomical and functional commonalities. The retina is...
-
Neuroimaging Biomarkers in Alzheimer’s Disease and Related Disorders
Since about 2017 neuroimaging biomarkers, particularly beta-amyloid and tau imaging, have become critical to screen Alzheimer’s disease (AD) patients...
-
Inflammation Biomarkers in Huntington’s Disease
Neurodegenerative diseases share many features, such as inflammation. Accumulating evidence support the role of neuroinflammation in the pathogenesis...
-
Metabolomic Biomarkers in Parkinson’s Disease
Metabolomics analysis has developed rapidly in recent decades and has become a powerful tool to understand comprehensive metabolic changes in...
-
Astrocytes in Huntington’s Disease Pathology: Implications for Biomarkers
Astrocytes are a main type of glial cell in the central nervous system (CNS) and are important for the maintenance of normal brain function,...
-
Utilization of fluid-based biomarkers as endpoints in disease-modifying clinical trials for Alzheimer’s disease: a systematic review
BackgroundClinical trials in Alzheimer’s disease (AD) had high failure rates for several reasons, including the lack of biological endpoints....
-
Blood-Based Biomarkers for Early Alzheimer’s Disease Diagnosis in Real-World Settings
As our knowledge about the biology of Alzheimer’s disease (AD) expands and we recognize the significance of early intervention for effective...