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Factors associated with the melanoma diagnostic interval in Ontario, Canada: a population-based study
BackgroundProtracted times to diagnosis of cancer can lead to increased patient anxiety, and in some cases, disease progression and worse outcomes....
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Diagnostic accuracy of circular RNA for diabetes Mellitus: a systematic review and diagnostic Meta-analysis
BackgroundThis study aimed to investigate the pooled diagnostic ability of circular RNA (circRNA) molecules for diabetes mellitus.
Methods ... -
A case with a trend of QT interval prolongation due to the introduction of methadone to a pancreatic cancer patient on levofloxacin
BackgroundAs methadone can prevent the development of opioid resistance, it has application in alleviating cancer-related pain that proves...
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Diagnostic Accuracy of Exosomal Long Noncoding RNAs in Diagnosis of NSCLC: A Meta-Analysis
PurposeGlobally, non-small cell lung cancer (NSCLC) is the primary cause of cancer-related mortality, both early and accurate diagnosis are essential...
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Diagnostic performance of circulating biomarkers for non-alcoholic steatohepatitis
There are no approved diagnostic biomarkers for at-risk non-alcoholic steatohepatitis (NASH), defined by the presence of NASH, high histological...
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Diagnostic Approaches of Prostate Cancer: When Is a Biopsy Required?
Prostate carcinoma is very common. Finding best diagnostic algorithm still remains the goal urologists try to reach. Mainstay for diagnosis is... -
Diagnostic performance of ultrasensitive rapid diagnostic test for the detection of Plasmodium falciparum infections in asymptomatic individuals in Kisangani, Northeast Democratic Republic of Congo
BackgroundUltrasensitive rapid diagnostic test (usRDT) was recently developed to improve the detection of low-density Plasmodium falciparum ...
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Treatment interval in curative treatment of colon cancer, does it impact (cancer free) survival? A non-inferiority analysis
BackgroundIn treatment of colon cancer, strict waiting-time targets are enforced, leaving professionals no room to lengthen treatment intervals when...
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Serum matrix metalloproteinase-7 for discriminating biliary atresia: a diagnostic accuracy and validation study
BackgroundPrompt and precise differential diagnosis of biliary atresia (BA) among cholestatic patients is of great importance. Matrix...
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Impact of treatment interval between neoadjuvant immunochemotherapy and surgery in lung squamous cell carcinoma
ObjectiveThe optimal timing for surgery following neoadjuvant immunochemotherapy for lung squamous cell carcinoma appears to be a topic of limited...
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Systematic Review and Meta-Analysis of the Diagnostic Accuracy of a Graded Gait and Truncal Instability Rating in Acutely Dizzy and Ataxic Patients
BackgroundIn patients presenting with acute prolonged vertigo and/or gait imbalance, the HINTS [Head-Impulse, Nystagmus, Test-of-Skew] are very...
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Diagnostic accuracy and clinical value of [68Ga]Ga-FAPI-46 PET/CT for staging patients with ovarian cancer: study protocol for a prospective clinical trial
Background[ 18 F]Fluorodeoxyglucose ([ 18 F]FDG) positron emission tomography (PET) is recommended during diagnostic work-up for ovarian cancer;...
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Assessment of Diagnostic Tests
Most of us are familiar with these definitions, so let us keep it brief, starting with a 2 x 2 table (Table 2.1). -
Post-diagnostic health behaviour scores and risk of prostate cancer progression and mortality
BackgroundIndividual behaviours are associated with prostate cancer (PC) progression. Behavioural scores, comprised of multiple risk factors, allow...
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CTC-Based Liquid Biopsies and Diagnostic Leukapheresis
Circulating tumor cells (CTCs) appear as ideal tissue surrogate to inform on molecular characteristics of systemic cancer for rational therapeutic... -
Diagnostic efficacy of contrast-enhanced gastric ultrasonography in staging gastric cancer: a meta-analysis
BackgroundAs comprehensive surgical management for gastric cancer becomes increasingly specialized and standardized, the precise differentiation...
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ESCCPred: a machine learning model for diagnostic prediction of early esophageal squamous cell carcinoma using autoantibody profiles
BackgroundEsophageal squamous cell carcinoma (ESCC) is a deadly cancer with no clinically ideal biomarkers for early diagnosis. The objective of this...
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Significant number of Plasmodium vivax mono-infections by PCR misidentified as mixed infections (P. vivax/P. falciparum) by microscopy and rapid diagnostic tests: malaria diagnostic challenges in Ethiopia
BackgroundPlasmodium vivax malaria is now recognized as a cause of severe morbidity and mortality, resulting in a substantial negative effect on...
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A diagnostic model for Parkinson’s disease based on circadian rhythm-related genes
BackgroundCircadian rhythm (CR) disturbance is intricately associated with Parkinson’s disease (PD). However, the involvement of CR-related...
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Mathematical Modeling and Biocybernetics in Medical Diagnostic Systems
This article reviews the most interesting reports of the “Mathematical modeling and biocybernetics” section of the XV International Scientific...