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Digitally managed larviciding as a cost-effective intervention for urban malaria: operational lessons from a pilot in São Tomé and Príncipe guided by the Zzapp system
BackgroundOnce a mainstay of malaria elimination operations, larval source management (LSM)—namely, the treatment of mosquito breeding habitats–has...
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Acoustic Baseline Monitoring of Marine Mammals Offshore West Africa: Using an Autonomous Surface Vessel
A marine mammal baseline monitoring program was initiated offshore São Tomé and Príncipe in 2018–2019. An AutoNaut autonomous or uncrewed surface...
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Epidemiology and Public Health Importance
This chapter presents information on the distribution of loiasis and factors explaining variations in prevalence levels. Data on the cases reported...
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Predictors of COVID-19 epidemics in countries of the World Health Organization African Region
Countries of the World Health Organization (WHO) African Region have experienced a wide range of coronavirus disease 2019 (COVID-19) epidemics. This...
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Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018
Anemia is a globally widespread condition in women and is associated with reduced economic productivity and increased mortality worldwide. Here we...
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Map** exclusive breastfeeding in Africa between 2000 and 2017
Exclusive breastfeeding (EBF)—giving infants only breast-milk (and medications, oral rehydration salts and vitamins as needed) with no additional...
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Mupirocin-resistant Staphylococcus aureus in Africa: a systematic review and meta-analysis
BackgroundMupirocin is widely used for nasal decolonization of Staphylococcus aureus to prevent subsequent staphylococcal infection in patients and...
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Medicines Regulation in Africa: Current State and Opportunities
Sound regulatory systems are critical for protecting public health against use of medical products which do not meet international standards of...
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Tracking development assistance and government health expenditures for 35 malaria-eliminating countries: 1990–2017
BackgroundDonor financing for malaria has declined since 2010 and this trend is projected to continue for the foreseeable future. These reductions...
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Cryptosporidium and Giardia in Africa: current and future challenges
Cryptosporidium and Giardia are important causes of diarrhoeal illness. Adequate knowledge of the molecular diversity and geographical distribution...
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High rate of detection of G8P[6] rotavirus in children with acute gastroenteritis in São Tomé and Príncipe
The burden of rotavirus infections greatly affects the low-income African countries. In the absence of epidemiological data on pediatric diarrhea in...
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Global fund financing to the 34 malaria-eliminating countries under the new funding model 2014–2017: an analysis of national allocations and regional grants
BackgroundThe Global Fund to Fight AIDS, Tuberculosis, and Malaria (GFATM) has been the largest financial supporter of malaria since 2002. In 2011,...
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Small-scale evaluation of the efficacy and residual activity of alpha-cypermethrin WG (250 g AI/kg) for indoor spraying in comparison with alpha-cypermethrin WP (50 g AI/kg) in India
BackgroundIndoor residual spraying (IRS) with different formulations of insecticides is being used for the control of mosquito vectors in many...
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Toxoplasma gondii infection: relationship between seroprevalence and risk factors among primary schoolchildren in the capital areas of Democratic Republic of São Tomé and Príncipe, West Africa
BackgroundThe status of Toxoplasma gondii infection among primary schoolchildren (PSC) of the Democratic Republic of São Tomé and Príncipe (DRSTP),...
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Application of loop-mediated isothermal amplification for malaria diagnosis during a follow-up study in São Tomé
BackgroundA reliable and simple test for the detection of malaria parasite is crucial in providing effective treatment and therapeutic follow-up,...
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The potential of anti-malarial compounds derived from African medicinal plants. Part I: A pharmacological evaluation of alkaloids and terpenoids
Traditional medicine caters for about 80% of the health care needs of many rural populations around the world, especially in develo** countries. In...
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Can malaria vector control accelerate the interruption of lymphatic filariasis transmission in Africa; capturing a window of opportunity?
BackgroundThe Global Programme to Eliminate Lymphatic Filariasis (GPELF) was launched in 2000, and nearly all endemic countries in the Americas,...
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In silico drug metabolism and pharmacokinetic profiles of natural products from medicinal plants in the Congo basin
PurposeDrug metabolism and pharmacokinetics (DMPK) assessment has come to occupy a place of interest during the early stages of drug discovery today....
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Epidemiology and Distribution of Peste des Petits Ruminants
Phylogenetically, based on the fusion (F) and nucleocapsid (N) genes, peste des petits ruminants virus (PPRV) can be classified into four distinct...
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The dominant Anopheles vectors of human malaria in Africa, Europe and the Middle East: occurrence data, distribution maps and bionomic précis
BackgroundThis is the second in a series of three articles documenting the geographical distribution of 41 dominant vector species (DVS) of human...
