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L31 Transposons of Hexacorallia: Distribution, Diversity, and Evolution
Abstract —Transposable elements (TEs) of eukaryotes—retrotransposons and DNA transposons—are nucleotide sequences that can move from locus to locus of...
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Structure and Diversity of Tc1/mariner DNA Transposons in the Genome of the Jellyfish Aurelia aurita
AbstractTransposable elements (DNA transposons and retrotransposons) are DNA sequences that have the ability to change their position within a...
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A unique eukaryotic lineage of composite-like DNA transposons encoding a DDD/E transposase and a His-Me finger homing endonuclease
BackgroundDNA transposons are ubiquitous components of eukaryotic genomes. A major group of them encode a DDD/E transposase and contain terminal...
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Phenotypically Unstable Mutations as Markers of Chromosomal Rearrangements Involving DNA Transposons
AbstractThe review analyzed the validity of using unstable alleles of Drosophila melanogaster genes to assess the rate of movement of mobile genetic...
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Transposons Associated with Antibiotic-Resistant Genes in Gram-Negative Bacteria
Transposons are a group of mobile genetic elements. Transposons can switch among various places of the genome, hence also called as jum** genes....
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Zvezda—A New Subfamily of Tc1-Like Transposons in Asterozoa Genomes
AbstractMobile genetic elements have a significant impact on the evolution of the genomes of living organisms. They are divided into two...
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Multiple horizontal transfer events of a DNA transposon into turtles, fishes, and a frog
Horizontal transfer of transposable elements (HTT) has been reported across many species and the impact of such events on genome structure and...
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Fitness costs of Tn1546-type transposons harboring the vanA operon by plasmid type and structural diversity in Enterococcus faecium
BackgroundThis study analyzed the genetic traits and fitness costs of vancomycin-resistant Enterococcus faecium (VREfm) blood isolates carrying Tn 1546...
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Screening a small hydrazide-hydrazone combinatorial library for targeting the STAT3 in monocyte-macrophages with insulated reporter transposons
The Signal Transducer and Activator of Transcription 3 (STAT3) pharmacological targeting is regarded as a prospective approach to treat cancer,...
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DNA damage and repair in age-related inflammation
Genomic instability is an important driver of ageing. The accumulation of DNA damage is believed to contribute to ageing by inducing cell death,...
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The structural diversity of CACTA transposons in genomes of Chenopodium (Amaranthaceae, Caryophyllales) species: specific traits and comparison with the similar elements of angiosperms
BackgroundCACTA transposable elements (TEs) comprise one of the most abundant superfamilies of Class 2 (cut-and-paste) transposons. Over recent...
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Software evaluation for de novo detection of transposons
Transposable elements (TEs) are major genomic components in most eukaryotic genomes and play an important role in genome evolution. However, despite...
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Non-canonical DNA structures in the human ribosomal DNA
Non-canonical structures (NCS) refer to the various forms of DNA that differ from the B-conformation described by Watson and Crick. It has been found...
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AcademH, a lineage of Academ DNA transposons encoding helicase found in animals and fungi
BackgroundDNA transposons are ubiquitous components of eukaryotic genomes. Academ superfamily of DNA transposons is one of the least characterized...
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Cas9-induced targeted integration of large DNA payloads in primary human T cells via homology-mediated end-joining DNA repair
The reliance on viral vectors for the production of genetically engineered immune cells for adoptive cellular therapies remains a translational...
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CRAG: de novo characterization of cell-free DNA fragmentation hotspots in plasma whole-genome sequencing
The fine-scale cell-free DNA fragmentation patterns in early-stage cancers are poorly understood. We developed a de novo approach to characterize the...
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DNA Methylation is Involved in Sex Determination in Spinach
DNA methylation plays a critical role in the modulation of gene expression. The role of DNA methylation in sex determination was investigated in...
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Chromatin and DNA Dynamics in Mouse Models of Liver Cancers
In recent years, important efforts have been made to understand how the expression of a specific gene repertoire correlates with chromatin...
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Transposons and satellite DNA: on the origin of the major satellite DNA family in the Chenopodium genome
Extensive and complex links exist between transposable elements (TEs) and satellite DNA (satDNA), which are the two largest fractions of eukaryotic...
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Intruder (DD38E), a recently evolved sibling family of DD34E/Tc1 transposons in animals
BackgroundA family of Tc1/mariner transposons with a characteristic DD38E triad of catalytic amino acid residues, named Intruder ( IT ), was...
