Search
Search Results
-
Contrast-Induced Nephropathy (CIN) and Biomarkers
Acute kidney injury (AKI) is a sudden loss of kidney function secondary to a variety of reasons. Contrast-induced nephropathy (CIN) is a form of AKI...
-
Contrast-Induced Nephropathy (CIN) and Biomarkers
Acute kidney injury (AKI) is a sudden loss of kidney function secondary to a variety of reasons. Contrast-induced nephropathy (CIN) is a form of AKI...
-
Contrast-induced nephropathy and oxidative stress: mechanistic insights for better interventional approaches
Contrast-induced nephropathy (CIN) or contrast-induced acute kidney injury (CI-AKI) is an iatrogenic acute kidney injury observed after intravascular...
-
Insights into the Therapeutic Potential of Phytoconstituents as an Epigenetic Modulators in Diabetic Nephropathy
Chronic diabetes is commonly associated with the development of nephropathy, which is a prevalent complication. Hyperglycemia is believed to initiate...
-
Multiple myeloma with acute light chain cast nephropathy
Light chain cast nephropathy (LCCN) is a leading cause of acute kidney injury (AKI) in patients with multiple myeloma (MM) and is now defined as a...
-
Prevention of contrast induced-acute kidney injury using coenzyme Q10 in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention
PurposeWe assessed the potential effect of CoQ10 administration for the prevention of contrast induced-acute kidney injury (CI-AKI) in patients with...
-
Nicotine exacerbates diabetic nephropathy through upregulation of Grem1 expression
BackgroundDiabetic nephropathy (DN) is a major complication of diabetes mellitus. Clinical reports indicate that smoking is a significant risk factor...
-
Identification of co-expressed central genes and transcription factors in acute myocardial infarction and diabetic nephropathy
BackgroundAcute myocardial infarction (AMI) and diabetic nephropathy (DN) are common clinical co-morbidities, but they are challenging to manage and...
-
Renal angiotensin I-converting enzyme-deficient mice are protected against aristolochic acid nephropathy
The renal renin-angiotensin system (RAS) is involved in the development of chronic kidney disease. Here, we investigated whether mice with reduced...
-
Wogonin upregulates SOCS3 to alleviate the injury in Diabetic Nephropathy by inhibiting TLR4-mediated JAK/STAT/AIM2 signaling pathway
BackgroundDiabetic nephropathy (DN) is a life-threatening renal disease and needs urgent therapies. Wogonin is renoprotective in DN. This study aimed...
-
Sestrin2 attenuates renal damage by regulating Hippo pathway in diabetic nephropathy
Glomerular mesangial cell proliferation and extracellular matrix accumulation contribute to the progression of diabetic nephropathy (DN). As a...
-
Tanshinone IIA is superior to paricalcitol in ameliorating tubulointerstitial fibrosis through regulation of VDR/Wnt/β-catenin pathway in rats with diabetic nephropathy
Glomerulosclerosis and tubulointerstitial fibrosis (TIF) are closely involved in the development of diabetic nephropathy (DN). Moreover, the...
-
Omics are Getting Us Closer to Understanding IgA Nephropathy
During the last decade, thanks to omics technologies, new light has been shed on the pathogenesis of many diseases. Genomics, epigenomics,...
-
Histone modification in podocyte injury of diabetic nephropathy
Diabetic nephropathy (DN), an important complication of diabetic microvascular disease, is one of the leading causes of end-stage renal disease...
-
Imbalance of T follicular helper cell subsets trigger the differentiation of pathogenic B cells in idiopathic membranous nephropathy
ObjectiveThis study aims to elucidate the role of T follicular helper (Tfh) cells and their subsets in idiopathic membranous nephropathy (IMN).
...
-
Modeling of Fabry disease nephropathy using patient derived human induced pluripotent stem cells and kidney organoid system
ObjectivesTo explore the possibility of kidney organoids generated using patient derived human induced pluripotent stem cells (hiPSC) for modeling of...
-
Fibroblast growth factor 21 attenuates salt-sensitive hypertension-induced nephropathy through anti-inflammation and anti-oxidation mechanism
BackgroundPatients with salt-sensitive hypertension are often accompanied with severe renal damage and accelerate to end-stage renal disease, which...
-
Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy
IgA nephropathy (IgAN) is a progressive form of kidney disease defined by glomerular deposition of IgA. Here we performed a genome-wide association...
-
Probiotics ameliorate IgA nephropathy by improving gut dysbiosis and blunting NLRP3 signaling
BackgroundRecently, a few studies have indicated a relationship between the gut microbiota and IgA nephropathy (IgAN). Whether the gut microbiota...
-
Evaluation of coenzyme Q10 combined with or without N-acetyl cysteine or atorvastatin for preventing contrast-induced kidney injury in diabetic rats
Combined antioxidants effect for prevention of contrast-induced nephropathy (CIN) remains unclear. This study assessed the potential protective...
