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Intragenomic rDNA variation - the product of concerted evolution, mutation, or something in between?
The classical model of concerted evolution states that hundreds to thousands of ribosomal DNA (rDNA) units undergo homogenization, making the...
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Histone protein profiling in rice reveals a correlation between canonical and noncanonical function and evolution
Histones epitomize the key protein module of chromatin and act as important signatures for many biological processes, such as replication, cell cycle...
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Current advances in primate genomics: novel approaches for understanding evolution and disease
Primate genomics holds the key to understanding fundamental aspects of human evolution and disease. However, genetic diversity and functional...
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Steering and controlling evolution — from bioengineering to fighting pathogens
Control interventions steer the evolution of molecules, viruses, microorganisms or other cells towards a desired outcome. Applications range from...
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Molecular Evolution
Molecular evolution occurs in the genome in the form of substitutions, insertion/deletion, recombination and gene conversion. The principles of...
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Spatial biology of cancer evolution
The natural history of cancers can be understood through the lens of evolution given that the driving forces of cancer development are mutation and...
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Epithelial and stromal co-evolution and complicity in pancreatic cancer
Pancreatic ductal adenocarcinomas are distinguished by their robust desmoplasia, or fibroinflammatory response. Dominated by non-malignant cells, the...
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5S Ribosomal DNA in the Family Plumbaginaceae
AbstractTandemly arranged repetitive regions (repeats) that encode 5S rRNA (5S rDNA) are an indispensable component of eukaryotic genomes. Typically,...
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p73 isoforms meet evolution of metastasis
Cancer largely adheres to Darwinian selection. Evolutionary forces are prominent during metastasis, the final and incurable disease stage, where...
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Assembly and Evolution of Poxviruses
Poxvirus assemblyPoxvirus assembly has been an intriguing area of research for several decades. While advancements in experimental techniques...
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Rapid evolution of insecticide resistance and patterns of pesticides usage in agriculture in the city of Yaoundé, Cameroon
BackgroundThe practice of agriculture in urban settings contributes to the rapid expansion of insecticide resistance in malaria vectors. However,...
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Evolution, Characteristics, and Clonal Expansion of Livestock-Associated Methicillin-Resistant Staphylococcus aureus (LA-MRSA): Global Perspectives
Epidemiological classification of methicillin-resistant Staphylococcus aureus (MRSA) as hospital-associated MRSA (HA-MRSA), community-associated MRSA...
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Evolution, Characteristics, and Clonal Expansion of Livestock-Associated Methicillin-Resistant Staphylococcus aureus (LA-MRSA): Global Perspectives
Epidemiological classification of methicillin-resistant Staphylococcus aureus (MRSA) as hospital-associated MRSA (HA-MRSA), community-associated MRSA...
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Evolution of tetraspanin antigens in the zoonotic Asian blood fluke Schistosoma japonicum
BackgroundDespite successful control efforts in China over the past 60 years, zoonotic schistosomiasis caused by Schistosoma japonicum remains a...
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Parallel subgenome structure and divergent expression evolution of allo-tetraploid common carp and goldfish
How two subgenomes in allo-tetraploids adapt to coexistence and coordinate through structure and expression evolution requires extensive studies. In...
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Convergent evolution of a genomic rearrangement may explain cancer resistance in hystrico- and sciuromorpha rodents
The rodents of hystricomorpha and sciuromorpha suborders exhibit remarkably lower incidence of cancer. The underlying genetic basis remains obscure....
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The 18S rRNA genes of Haemoproteus (Haemosporida, Apicomplexa) parasites from European songbirds with remarks on improved parasite diagnostics
BackgroundThe nuclear ribosomal RNA genes of Plasmodium parasites are assumed to evolve according to a birth-and-death model with new variants...
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The evolution of S100A7 in primates: a model of concerted and birth-and-death evolution
The human S100A7 resides in the epidermal differentiation complex (EDC) and has been described as a key effector of innate immunity. In humans, there...
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Mutation load at a mimicry supergene sheds new light on the evolution of inversion polymorphisms
Chromosomal inversions are ubiquitous in genomes and often coordinate complex phenotypes, such as the covariation of behavior and morphology in many...
