Search
Search Results
-
An epigenetic hypothesis for ovarian cancer prevention by oral contraceptive pill use
BackgroundOvarian cancer is the second most common gynecological cancer type after uterine cancers. In 2020, according to worldwide statistics, there...
-
Comparison of the cytokine responses to acute strength exercise between oral contraceptive users and naturally cycling women
PurposeCytokines are released as part of an inflammatory reaction in response to strength exercise to initiate muscle repair and morphological...
-
Beyond the pill: contraception and the prevention of hereditary ovarian cancer
BRCA1 and BRCA2 mutation carriers face an elevated lifetime risk of develo** ovarian cancer. Oral contraceptives have been shown to significantly...
-
The acute effect of the menstrual cycle and oral contraceptive cycle on measures of body composition
PurposeThis study aimed to investigate the effect of fluctuating female hormones during the menstrual cycle (MC) and oral contraceptive (OC) cycle on...
-
Temporal changes in blood oxidative stress biomarkers across the menstrual cycle and with oral contraceptive use in active women
PurposeTo examine the temporal changes in blood oxidative stress biomarkers in recreationally-trained women that were naturally-cycling (WomenNC) or...
-
Fasted plasma asprosin concentrations are associated with menstrual cycle phase, oral contraceptive use and training status in healthy women
PurposeAsprosin, an orexigenic hormone that stimulates hepatic glucose release, is elevated in insulin resistance and associated with obesity. Plasma...
-
Do E2 and P4 contribute to the explained variance in core temperature response for trained women during exertional heat stress when metabolic rates are very high?
PurposeWomen remain underrepresented in the exercise thermoregulation literature despite their participation in leisure-time and occupational...
-
A prospective investigation of oral contraceptive use and breast cancer mortality: findings from the Swedish women’s lifestyle and health cohort
BackgroundThe association between oral contraceptive (OC) use and long-term mortality remains uncertain and previous studies have reported...
-
Potential factors contributing to observed sex differences in virtual-reality-induced sickness
Virtual reality (VR) technology has been widely adopted for several professional and recreational applications. Despite rapid innovation in hardware...
-
-
Association between allostatic load and breast cancer risk: a cohort study
BackgroundAllostatic load (AL) reflects the collective load of chronic stress during lifetime. Previous studies have shown that higher AL is...
-
Pharmacokinetics of Long-Acting Aqueous Nano-/Microsuspensions After Intramuscular Administration in Different Animal Species and Humans—a Review
Formulating aqueous suspensions is an attractive strategy to incorporate poorly water-soluble drugs, where the drug release can be tailored to...
-
Impact of hormonal contraception on endometrial histology in patients with Lynch syndrome, a retrospective pilot study
Hormonal contraception (HC) is a well-recognized protection against endometrial cancer (EC) in the general population. It has not been established if...
-
Repurposing simvastatin in cancer treatment: an updated review on pharmacological and nanotechnological aspects
Management of cancer is challenging due to non-targeting and high side effect issues. Drug repurposing is an innovative method for employing...
-
Alcohol consumption and cancer incidence in women: interaction with smoking, body mass index and menopausal hormone therapy
BackgroundAlcohol consumption has been associated with increased risks of certain site-specific cancers and decreased risks of some other cancers....
-
Clinical Translation: Targeting the Estrogen Receptor
Estrogen Receptor alpha (ERα) stands as one of the most successfully prosecuted drug targets in oncology, beginning with the approval of tamoxifen...
-
Educational level and characteristics of invasive breast cancer: findings from a French prospective cohort
PurposeBreast cancer (BC) characteristics are known to influence patients survival. Social differences have been reported by previous studies for...
-
Perioperative tislelizumab plus chemotherapy for locally advanced resectable thoracic esophageal squamous cell carcinoma trial: a prospective single-arm, phase II study (PILOT trial)
BackgroundThe promising therapeutic outcomes of neoadjuvant immunotherapy combined with chemotherapy in the treatment of locally advanced esophageal...
-
Exogenous hormone use, reproductive factors and risk of intrahepatic cholangiocarcinoma among women: results from cohort studies in the Liver Cancer Pooling Project and the UK Biobank
BackgroundIntrahepatic cholangiocarcinoma (ICC) arises from cholangiocytes in the intrahepatic bile duct and is the second most common type of liver...
-
Whole-exome sequencing reveals candidate high-risk susceptibility genes for endometriosis
BackgroundEndometriosis is a common, chronic disease among fertile-aged women. Disease course may be highly invasive, requiring extensive surgery....
