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Chronic active Epstein-Barr virus infection with reinfection of SARS-CoV-2: a case report
We describe the case of a 57-year-old male with jaundice, abdominal distension and fatigue. He was diagnosed as chronic active Epstein-Barr virus...
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The opposing effect of acute and chronic Toxoplasma gondii infection on tumor development
BackgroundThe interplay between Toxoplasma gondii infection and tumor development is intriguing and not yet fully understood. Some studies showed...
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Chronic Hemorrhagic Anemia Caused by Hookworm Infection: A Case Report
PurposeHookworm infection is one of the causes of long-term chronic hemorrhagic anemia in patients. This article reports a case of chronic severe...
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Chronic LCMV infection regulates the effector T cell response by inducing the generation of less immunogenic dendritic cells
Chronic viral infection impairs systemic immunity in the host; however, the mechanism underlying the dysfunction of immune cells in chronic viral...
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Chronic COVID-19 infection in an immunosuppressed patient shows changes in lineage over time: a case report
BackgroundThe COVID-19 pandemic, caused by the Severe Acute Respiratory Syndrome Coronavirus 2 virus, emerged in late 2019 and spready globally. Many...
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Increased risk of chronic fatigue syndrome following infection: a 17-year population-based cohort study
BackgroundPrevious serological studies have indicated an association between viruses and atypical pathogens and Chronic Fatigue Syndrome (CFS). This...
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Comparison of intestinal flora between patients with chronic and advanced Schistosoma japonicum infection
BackgroundSchistosoma japonicum infection is an important public health problem, imposing heavy social and economic burdens in 78 countries...
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Sex Differences in HIV Infection
Biological sex has wide-ranging impacts on HIV infection spanning differences in acquisition risk, the pathogenesis of untreated infection, impact of... -
Inefficient antiviral response in reconstituted small-airway epithelium from chronic obstructive pulmonary disease patients following human parainfluenza virus type 3 infection
Chronic obstructive pulmonary disease (COPD) affects over 250 million individuals globally and stands as the third leading cause of mortality....
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Lentinan has a beneficial effect on cognitive deficits induced by chronic Toxoplasma gondii infection in mice
BackgroundToxoplasma gondii ( T. gondii ) is increasingly considered a risk factor for neurodegenerative diseases. However, there is only limited...
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Differential transcriptome study on the damage of testicular tissues caused by chronic infection of T. gondii in mice
BackgroundToxoplasma gondii is an intracellular protozoan parasite that is widely distributed in humans and warm-blooded animals. T. gondii chronic...
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Shared genetic factors and causal association between chronic hepatitis C infection and diffuse large B cell lymphoma
BackgroundEpidemiological research and systematic meta-analyses indicate a higher risk of B-cell lymphomas in patients with chronic hepatitis C virus...
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Chronic hyperglycemia impairs anti-microbial function of macrophages in response to Mycobacterium tuberculosis infection
Diabetes mellitus (DM) is a major risk factor for tuberculosis (TB), though the underlying mechanisms linking DM and TB remain ambiguous. Macrophages...
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Modeling Chronic Coccidioidomycosis in Mice
Coccidioidomycosis, caused by the dimorphic pathogens Coccidioides posadasii and C. immitis, is a fungal disease endemic to the southwestern United... -
CTLA4+CD4+CXCR5−FOXP3+ T cells associate with unfavorable outcome in patients with chronic HBV infection
BackgroundA major barrier to achieving a favorable outcome of chronic HBV infection is a dysregulated HBV-specific immune response resulting from...
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Assessing Biomarkers in Viral Infection
Current biomarkers to assess the risk of complications of both acute and chronic viral infection are suboptimal. Prevalent viral infections like... -
Assessment of the performance of haematological and non-invasive fibrotic indices for the monitoring of chronic HBV infection: a pilot study in a Ghanaian population
ObjectiveHaematological and liver fibrotic markers could be appreciably utilized for effective monitoring of Chronic Hepatitis B viral (HBV)...
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Chronic Prostatitis
The term “chronic prostatitis” in everyday practice defines a symptomatic prostatic disease that continues for a long time (at least 3–6 months). A... -
Two genetic variants in the SRD5A2 gene are found to be associated with sex differences in the disease characteristics of patients with chronic hepatitis B virus infection
BackgroundTo examine the expression characteristics of single nucleotide polymorphisms (SNPs) in the SRD5A2 gene and investigate their potential...
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Differences in neuroinflammation in people who started antiretroviral treatment during primary versus chronic HIV infection: an 18kDa Translocator protein (TSPO) positron emission tomography (PET) study
Persistent inflammation is described in people with HIV (PWH) on antiretroviral treatment (ART). Early ART initiation is associated with reduced...