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Synbiotics in Cervical Cancer
The gut microbiota is usually regarded as one of the most crucial aspects in maintaining homeostasis. Probiotic microbes have been proven to come up... -
Biosimilar in Cervical Cancer
Cervical Cancer is a serious health concern possessing a serious health problem in women. This chapter provides a comprehensive overview of the role... -
Immunotherapy for Cervical Cancer
Cervical cancer is a highly prevalent gynecological malignancy worldwide, and it is associated with high-risk human papillomavirus (HPV) infection.... -
Cancer/testis-45A1 promotes cervical cancer cell tumorigenesis and drug resistance by activating oncogenic SRC and downstream signaling pathways
BackgroundCancer/testis antigen-45A1 (CT45A1) is overexpressed in various types of cancer but is not expressed in healthy women. The role of CT45A1...
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Panobinostat (LBH589) combined with AM1241 induces cervical cancer cell apoptosis through autophagy pathway
PurposeThe study aims to investigate the apoptotic effects of combining LBH589 and AM1241 (a selective CB2 receptor agonist) on cervical cancer cells...
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The promoting effect and mechanism of Nrf2 on cell metastasis in cervical cancer
BackgroundCervical cancer (CC) has poor prognosis and high mortality rate for its metastasis during the disease progression. Epithelial-mesenchymal...
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Regulatory T cell frequency in peripheral blood of women with advanced cervical Cancer including women living with HIV
BackgroundPersistent high-risk Human papillomavirus (HR-HPV) infections are the main cause of cervical cancer. Cumulative evidence implicates...
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Hypoxic tumor cell-derived small extracellular vesicle miR-152-3p promotes cervical cancer radioresistance through KLF15 protein
BackgroundRadiotherapy is widely used in treating cervical cancer patients, however, radioresistance unavoidably occurs and seriously affects the...
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Microendoscopy in vivo for the pathological diagnosis of cervical precancerous lesions and early cervical cancer
BackgroundCervical cancer is an important public health problem. Conventional colposcopy is inefficient in the diagnosis of cervical lesions and...
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HPV16-miRNAs exert oncogenic effects through enhancers in human cervical cancer
BackgroundCervical cancer is a human papillomavirus (HPV)-related disease. HPV type 16 (HPV16), which is the predominant cause of cervical cancer,...
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Understanding the Role of Synbiotics in Prevention and Management of Cervical Cancer
Cervical cancer appeared to be the fourth most common cancer among women worldwide and Human Papillomavirus (HPV) is identified as the primary causal... -
Cytotoxic effect of disulfiram/copper on human cervical cancer cell lines and LGR5-positive cancer stem-like cells
BackgroundTumor resistance is a global challenge for tumor treatment. Cancer stem cells (CSCs) are the main population of tumor cells for drug...
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Differential proteomics reveals overexpression of ferroptosis-related proteins in cervical cancer tissue
Cervical cancer, the fourth most common female cancer, is one of the major global health challenges. Because of the high prevalence rate, women are...
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MUC1 promotes cervical squamous cell carcinoma through ERK phosphorylation-mediated regulation of ITGA2/ITGA3
In contrast to the decreasing trends in developed countries, the incidence and mortality rates of cervical squamous cell carcinoma in China have...
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miR-34a negatively regulates cell cycle factor Cdt2/DTL in HPV infected cervical cancer cells
MicroRNAs have emerged as an important regulator of cell cycle and various other cellular processes. Aberration in microRNAs has been linked with...
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Anti-Cancer Effects of Disulfiram in Cervical Cancer Cell Lines Are Mediated by Both Autophagy and Apoptosis
Disulfiram (DSF), which is used to treat alcohol dependence, has been reported to have anticancer effects in various malignant tumors. We studied the...
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Highlighting the role of CD44 in cervical cancer progression: immunotherapy’s potential in inhibiting metastasis and chemoresistance
Cervical cancer affects thousands of women globally with recurring high-risk HPV infections being at the centre of cervical pathology. Oncological...
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Uncharted Potentials of Synbiotics in Treatment of Cervical and Ovarian Cancer
Cancer is the one of the most prevalent causes of the deaths globally and also a major hindrance to achieve the desired life expectancy in most of... -
NSUN6-mediated 5-methylcytosine modification of NDRG1 mRNA promotes radioresistance in cervical cancer
BackgroundRadioresistance is the leading cause of death in advanced cervical cancer (CC). Dysregulation of RNA modification has recently emerged as a...
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Ultrasound-based radiomics machine learning models for diagnosing cervical lymph node metastasis in patients with non-small cell lung cancer: a multicentre study
BackgroundCervical lymph node metastasis (LNM) is an important prognostic factor for patients with non-small cell lung cancer (NSCLC). We aimed to...