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Computer simulation-based nanothermal field and tissue damage analysis for cardiac tumor ablation
Radiofrequency ablation is a nominally invasive technique to eradicate cancerous or non-cancerous cells by heating. However, it is still hampered to...
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In-Silico Deep Reinforcement Learning for Effective Cardiac Ablation Strategy
PurposeWe propose an in-silico deep reinforcement learning scheme that combines a computer simulation model of cardiac tissue and deep reinforcement...
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Surgical Ablation of Cardiac Tissue with Nanosecond Pulsed Electric Fields in Swine
BackgroundMyocardial tissue can be ablated by the application nanosecond pulsed fields (nsPEFs). The applied electric fields irreversibly...
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Dual-energy lattice-tip ablation system for persistent atrial fibrillation: a randomized trial
Clinical outcomes of catheter ablation for atrial fibrillation (AF) are suboptimal due, in part, to challenges in achieving durable lesions. Although...
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Noninvasive cardiac radioablation for ventricular tachycardia: dosimetric comparison between linear accelerator- and robotic CyberKnife-based radiosurgery systems
BackgroundFew dosimetric comparisons have been published between linear accelerator (LA)-based systems and CyberKnife (CK)-based robotic radiosurgery...
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Pulmonary Vein Morphology in Patients Undergoing Catheter Ablation of Atrial Fibrillation
PurposeVariations in the anatomy of pulmonary veins can influence selection of approaches of atrial fibrillation catheter ablation. Therefore,...
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Left atrial volume by cardiac CTA prior to catheter ablation: comparison to echocardiography and association with recurrent atrial fibrillation
ObjectiveLeft atrial volume index (LAVI) by echocardiography can be challenging and its accuracy is highly dependent on image quality. Cardiac...
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Ablation catheter–induced mechanical deformation in myocardium: computer modeling and ex vivo experiments
Cardiac catheter ablation requires an adequate contact between myocardium and catheter tip. Our aim was to quantify the relationship between the...
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Dual genetic tracing reveals a unique fibroblast subpopulation modulating cardiac fibrosis
After severe heart injury, fibroblasts are activated and proliferate excessively to form scarring, leading to decreased cardiac function and...
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Cardiac Development at a Single-Cell Resolution
Mammalian cardiac developmentCardiacdevelopment is a complex, multistage process. Though traditional lineage tracing studies have characterized the...
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Human Cardiac Development
Many aspects of heart development are topographically complex and require three-dimensional (3D) reconstruction to understand the pertinent...
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The Impact of Standard Ablation Strategies for Atrial Fibrillation on Cardiovascular Performance in a Four-Chamber Heart Model
PurposeAtrial fibrillation is one of the most frequent cardiac arrhythmias in the industrialized world and ablation therapy is the method of choice...
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Atrial fibrillation episode patterns as predictor of clinical outcome of catheter ablation
Methods for characterization of atrial fibrillation (AF) episode patterns have been introduced without establishing clinical significance. This study...
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Quantification of Mechanical Characteristics of Conventional Steerable Ablation Catheters for Treatment of Atrial Fibrillation Using a Heart Phantom
PurposeAccurate and reliable catheter navigation is important in formation of adequate lesions during radiofrequency cardiac catheter ablation. To...
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Disturbance of suprachiasmatic nucleus function improves cardiac repair after myocardial infarction by IGF2-mediated macrophage transition
Suprachiasmatic nucleus (SCN) in mammals functions as the master circadian pacemaker that coordinates temporal organization of physiological...
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Safety of pulsed field ablation in more than 17,000 patients with atrial fibrillation in the MANIFEST-17K study
Pulsed field ablation (PFA) is an emerging technology for the treatment of atrial fibrillation (AF), for which pre-clinical and early-stage clinical...
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Feasibility of Linear Irreversible Electroporation Ablation in the Coronary Sinus
IntroductionPrevious studies demonstrated that the coronary sinus (CS) is an important target for ablation in persistent atrial fibrillation....
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Unsupervised deep consistency learning adaptation network for cardiac cross-modality structural segmentation
AbstractDeep neural networks have recently been succeessful in the field of medical image segmentation; however, they are typically subject to...
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Cardiac Development and Animal Models of Congenital Heart Defects
The major events of cardiac development, including early heart formation, chamber morphogenesis and septation, and conduction system and coronary...
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Advances of Liquid Biopsy for Diagnosis of Atrial Fibrillation and Its Recurrence After Ablation in Clinical Application
Atrial fibrillation (AF) is a common arrhythmia disease with high morbidity in clinical practice and leads to stroke, heart failure, peripheral...