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Showing 1-19 of 19 results

  1. Whole-brain irradiation with hippocampal sparing and dose escalation on metastases: neurocognitive testing and biological imaging (HIPPORAD) – a phase II prospective randomized multicenter trial (NOA-14, ARO 2015–3, DKTK-ROG)

    Background

    Whole brain radiation therapy (WBRT) is the standard therapy for multiple brain metastases. However, WBRT has a poor local tumor control...

    Anca-Ligia Grosu, Lars Frings, ... Ilinca Popp in BMC Cancer
    Article Open access 08 June 2020

  2. Experimental and Preclinical Tools to Explore the Main Neurological Impacts of Brain Irradiation: Current Insights and Perspectives

    Radiation therapy is a powerful tool in the treatment of primary and metastatic cancers of the brain. However, brain tissue tolerance is limited, and...
    Laura Mouton, Monica Ribeiro, ... Pierre Verrelle in Brain Tumors
    Protocol 2021

  3. Feasibility of hippocampus-sparing VMAT for newly diagnosed glioblastoma treated by chemoradiation: pattern of failure analysis

    Background

    To identify the pattern of failure and oncological safety of hippocampus (HC)-sparing IMRT (HSRT) in newly diagnosed glioblastoma (GBM)...

    Chan Woo Wee, Kyung Su Kim, ... In Ah Kim in Radiation Oncology
    Article Open access 06 May 2020

  4. Craniopharyngioma in Pediatrics and Adults

    Craniopharyngiomas are rare malignancies of dysembryogenic origin, involving the sellarSellar and parasellarParasellar areas. These low-grade,...
    Martina Piloni, Filippo Gagliardi, ... Pietro Mortini in Human Brain and Spinal Cord Tumors: From Bench to Bedside. Volume 2
    Chapter 2023

  7. Hippocampal dosimetry correlates with the change in neurocognitive function after hippocampal sparing during whole brain radiotherapy: a prospective study

    Background

    Whole brain radiotherapy (WBRT) has been the treatment of choice for patients with brain metastases. However, change/decline of...

    **-Fang Tsai, Chi-Cheng Yang, ... Shinn-Yn Lin in Radiation Oncology
    Article Open access 10 December 2015

  8. Radioprotection as a Method to Enhance the Therapeutic Ratio of Radiotherapy

    Radiotherapy is a commonly used local and regional treatment for cancer. Although important advances in radiation treatment delivery have been made...
    Su I. Chung, DeeDee K. Smart, ... Deborah E. Citrin in Increasing the Therapeutic Ratio of Radiotherapy
    Chapter 2017

  11. Hippocampal proton MR spectroscopy as a novel approach in the assessment of radiation injury and the correlation to neurocognitive function impairment: initial experiences

    Background

    The hippocampus is considered as the main radiosensitive brain structure responsible for postradiotherapy cognitive decline. We...

    Petr Pospisil, Tomas Kazda, ... Radim Jancalek in Radiation Oncology
    Article Open access 17 October 2015

  12. Why and how to spare the hippocampus during brain radiotherapy: the develo** role of hippocampal avoidance in cranial radiotherapy

    The goal of this review is to summarize the rationale for and feasibility of hippocampal sparing techniques during brain irradiation. Radiotherapy is...

    Tomas Kazda, Radim Jancalek, ... Nadia N Laack in Radiation Oncology
    Article Open access 16 June 2014

  13. Brain Metastases: The Application of Stereotactic Radiosurgery and Technological Advances

    The purpose of this chapter is to provide a comprehensive review of the use of stereotactic radiosurgery (SRS) in patients with brain metastases. We...
    Siavash Jabbari, Lijun Ma, ... Arjun Sahgal in Tumors of the Central Nervous System, Volume 12
    Chapter 2014

  14. Palliative Radiation Therapy

    Radiation therapy is the field of oncology that uses ionizing radiation to kill malignant cells, by disturbing cellular processes, preventing a...
    Fabio Luis Cury, George Shenouda in Experimental and Clinical Metastasis
    Chapter 2013

  16. Radiation Therapy of CNS Metastases

    Radiation treatment of central nervous system (CNS) metastases, particularly brain metastasis, is changing. The role of radiation for intraaxial...
    DeeDee Smart in Central Nervous System Metastasis, the Biological Basis and Clinical Considerations
    Chapter 2012

  17. Radiation Biology and Therapy of Tumors of the Central Nervous System

    Interaction of ionizing radiation with any biological material results in uneven energy deposition, which results in a variety of chemical...
    Nalin Gupta, John R. Fike, ... Dennis F. Deen in Brain Tumors
    Chapter 2005

  18. A Critical Review of the Clinical Effects of Therapeutic Irradiation Damage to the Brain: The Roots of Controversy

    We critically examined the damaging affects of therapeutic irradiation by comparing results from cross-disciplinary studies of early- and...

    Carol L. Armstrong, Kunsang Gyato, ... Zelig A Tochner in Neuropsychology Review
    Article 01 March 2004

  19. Abstracts

    in Genetics in Medicine
    Article 01 July 2004
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