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Research diagnostic criteria for Alzheimer’s disease: findings from the LipiDiDiet randomized controlled trial
BackgroundTo explore the utility of the International Working Group (IWG)-1 criteria in recruitment for Alzheimer’s disease (AD) clinical trials, we...
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Machine Learning in Multiple Sclerosis
Multiple sclerosis (MS) is characterized by inflammatory activity and neurodegeneration, leading to the accumulation of damage to the central nervous...
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Analysis of miRNA Expression from the DLK1-DIO3 Locus in CD4+ and CD14+ Cells in Relapsing-Remitting Multiple Sclerosis
Objectives. To analyze the expression of several previously unstudied miRNAs from the DLK1-DIO3 locus in blood mononuclear cells (PBMC) and their CD14
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The rs6265 Polymorphism of the BDNF Gene in the Population of Patients with Multiple Sclerosis in the Tomsk Region
Objectives . To study the effects of the rs6265 polymorphism of the brain-derived neurotrophic factor ( BDNF ) gene on the risk of develo** multiple...
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Severe CTE and TDP-43 pathology in a former professional soccer player with dementia: a clinicopathological case report and review of the literature
In the last decades, numerous post-mortem case series have documented chronic traumatic encephalopathy (CTE) in former contact-sport athletes, though...
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Periodic Limb Movements during Sleep and the Clinical-Morphological Signs of Cerebral Microangiopathy
Objectives. To establish the relationship between the extent of white matter lesions and the degree of reductions in cognitive functions with...
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Dynamic and static changes of amplitude of low-frequency fluctuations in anti‑N‑methyl‑D‑aspartate receptor encephalitis
BackgroundPrevious neuroimaging research has examined static local brain activity changes in patients with anti-N-methyl-d-aspartate receptor...
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Rhombomere 5 r5
The structures of the auditory pathways (see Sect. 9.1.6 Nuclei of the superior olivary complex) have been dealt together with the cochlear nuclei...
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D1 Receptor Blockade Suppresses the Function of Th-17 Cells in Multiple Sclerosis
Objective. To study the direct influence of dopamine D 1 receptor antagonists on the functions of Th17 cells in multiple sclerosis (MS) in vitro. Materi...
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Classification of Parkinson’s disease using a region-of-interest- and resting-state functional magnetic resonance imaging-based radiomics approach
To investigate the value of combining amplitude of low-frequency fluctuations-based radiomics and the support vector machine classifier method in...
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Aberrant stability of brain functional architecture in cirrhotic patients with minimal hepatic encephalopathy
To investigate the stability changes of brain functional architecture and the relationship between stability change and cognitive impairment in...
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Clinical outcomes up to 9 years after [18F]flutemetamol amyloid-PET in a symptomatic memory clinic population
BackgroundPrevious studies demonstrated increases in diagnostic confidence and change in patient management after amyloid-PET. However, studies...
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Current Perspectives in the MRI Diagnosis of Multiple Sclerosis: The 2016 Revised MRI Criteria
MRI scanning is the main widely used diagnostic method for multiple sclerosis (MS). This article discusses the current state of the question of the...
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Brain structure and perfusion in relation to serum renal function indexes in healthy young adults
Prior neuroimaging studies of the relationship between the kidney and the brain have been limited to clinical populations and have largely relied on...
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Simultaneously decreased temporal variability and enhanced variability-strength coupling of emotional network connectivities are related to positive symptoms in patients with schizophrenia
We hypothesize that decreased temporal variability of emotional network connectivities, corresponding to a continual state of hyperactivity, may play...
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Molecular Biomarkers in the Cerebrospinal Fluid in Multiple Sclerosis
Multiple sclerosis (MS) is a chronic autoimmune disease affecting the spinal cord and brain. Detection of the disease at its initial stages is a...
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Right temporal variant frontotemporal dementia is pathologically heterogeneous: a case-series and a systematic review
Although the right temporal variant frontotemporal dementia (rtvFTD) is characterised by distinct clinical and radiological features, its underlying...
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Rationale and design of the “NEurodegeneration: Traumatic brain injury as Origin of the Neuropathology (NEwTON)” study: a prospective cohort study of individuals at risk for chronic traumatic encephalopathy
BackgroundRepetitive head injury in contact sports is associated with cognitive, neurobehavioral, and motor impairments and linked to a unique...
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Tau-related grey matter network breakdown across the Alzheimer’s disease continuum
BackgroundChanges in grey matter covariance networks have been reported in preclinical and clinical stages of Alzheimer’s disease (AD) and have been...
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Computer-Aided Diagnosis and Prediction in Brain Disorders
Computer-aided methods have shown added value for diagnosing and predicting brain disorders and can thus support decision making in clinical care and...