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Investigating the benefits of targeted selective treatment according to average daily weight gain against gastrointestinal nematodes in Morada Nova lambs
The objective of this study was to evaluate a method of targeted selective treatment (TST) of Morada Nova lambs, based on the average daily weight...
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Recombinant AAV Production
The insect cell-baculovirus expression vector (IC-BEV) platform has enabled small research-scale and large commercial-scale production of recombinant...
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A neuron–glia lipid metabolic cycle couples daily sleep to mitochondrial homeostasis
Sleep is thought to be restorative to brain energy homeostasis, but it is not clear how this is achieved. We show here that Drosophila glia exhibit a...
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Re-evaluation of a microbiological acceptable daily intake for tylosin based on its impact on human intestinal microflora
As veterinary drugs available for fish is very restricted, there is growing trials for repurposing livestock drugs as aquatic animal drugs. Tylosin...
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Exposure to Aluminum in Daily Life and Alzheimer’s Disease
Aluminum has often been regarded as not having a significant health hazard. Consequently, aluminum-containing agents have been used in the...
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Design of a Production Planning System in a Pharmaceutical Factory: Spreadsheet Model and Case Study
PurposeThis work focuses on develo** a production planning tool for small- and medium-sized enterprises (SMEs) in pharmaceutical manufacturing to...
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Viruses contribute to microbial diversification in the rumen ecosystem and are associated with certain animal production traits
BackgroundThe rumen microbiome enables ruminants to digest otherwise indigestible feedstuffs, thereby facilitating the production of high-quality...
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Bezafibrate Rescues Mitochondrial Encephalopathy in Mice via Induction of Daily Torpor and Hypometabolic State
Leigh syndrome (LS) is one of the most common mitochondrial encephalopathy diseases in infants. To date, there is still an absence of effective...
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Effects of melatonin on rumen microorganisms and methane production in dairy cow: results from in vitro and in vivo studies
BackgroundMethane (CH 4 ) is a major greenhouse gas, and ruminants are one of the sources of CH 4 which is produced by the rumen microbiota....
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Scalable production of tissue-like vascularized liver organoids from human PSCs
The lack of physiological parity between 2D cell culture and in vivo culture has led to the development of more organotypic models, such as...
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Rabbit Maternal Behavior: A Perspective from Behavioral Neuroendocrinology, Animal Production, and Psychobiology
Rabbit maternal behavior (MB) impacts meat and fur production on the farm, survival of the species in the wild, and pet welfare. Specific...
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Comparison of different transient gene expression systems for the production of a new humanized anti-HER2 monoclonal antibody (Hersintuzumab)
BackgroundProducing therapeutic proteins can be done quickly and on a large scale through Transient Gene Expression (TGE). Chinese hamster ovary...
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Matrine Mediated Immune Protection in MS by Regulating Gut Microbiota and Production of SCFAs
There is clearly an unmet need for more effective and safer treatments for multiple sclerosis (MS). Our previous studies showed a significant...
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Measurements of cerebrospinal fluid production: a review of the limitations and advantages of current methodologies
Cerebrospinal fluid (CSF) is an essential and critical component of the central nervous system (CNS). According to the concept of the “third...
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LipNanoCar Technology – A Versatile and Scalable Technology for the Production of Lipid Nanoparticles
The extensive knowledge in the miniemulsion technique used in biocatalysis applications by the authors allowed the development of drug delivery...
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Cows as Bioreactors for the Production of Nutritionally and Biomedically Significant Proteins
Dairy and beef cattle make a vital contribution to global nutritionNutrition, and since their domestication, they have been continuously exposed to...
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Production of human spinal-cord organoids recapitulating neural-tube morphogenesis
Human spinal-cord-like tissues induced from human pluripotent stem cells are typically insufficiently mature and do not mimic the morphological...
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Development of a Prototype, Once-Daily, Modified-Release Formulation for the Short Half-Life RIPK1 Inhibitor GSK2982772
PurposeGSK2982772 is a selective inhibitor of receptor-interacting protein kinase-1, with a 2–3 h half-life. This study evaluated if a once-daily...
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Incidence of catheter-associated urinary tract infections by Gram-negative bacilli and their ESBL and carbapenemase production in specialized hospitals of Bahir Dar, northwest Ethiopia
BackgroundCatheter-associated urinary tract infections (CAUTIs) due to multidrug-resistant Gram-negative bacilli (GNB) is a common concern globally....
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Relationship Between Dynamic Strength Index and Early Force Production of Isometric Mid-Thigh Pull
PurposeDynamic strength index (DSI) and percentage of isometric mid-thigh pull (IMTP) peak force (PF) produced during early epoch, expressed as a...
