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Neuronal types in the mouse amygdala and their transcriptional response to fear conditioning
The amygdala is a brain region primarily associated with emotional response. The use of genetic markers and single-cell transcriptomics can provide...
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Somatosensory cortex and central amygdala regulate neuropathic pain-mediated peripheral immune response via vagal projections to the spleen
Pain involves neuroimmune crosstalk, but the mechanisms of this remain unclear. Here we showed that the splenic T helper 2 (T H 2) immune cell response...
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Alteration of serotonin release response in the central nucleus of the amygdala to noxious and non-noxious mechanical stimulation in a neuropathic pain model rat
Previously, we found that serotonin (5-HT) release in the central nucleus of the amygdala (CeA) of anesthetized rats decreases in response to...
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An amygdala-centered effective connectivity network in trait anxiety
Previous studies have established that the amygdala plays an important role in trait anxiety. However, there remains limited knowledge regarding the...
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The relationship between alcohol consumption and amygdala volume in a community-based sample
Most prior studies have reported decreased amygdala volume in those with a history of alcohol use disorder. Decreased amygdala volume associated with...
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Neural Integration of Audiovisual Sensory Inputs in Macaque Amygdala and Adjacent Regions
Integrating multisensory inputs to generate accurate perception and guide behavior is among the most critical functions of the brain. Subcortical...
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Amygdala structure and function and its associations with social-emotional outcomes in a low-risk preterm sample
Amygdala atypical volume development and functional connectivity (FC) at small gestational ages (GA) have been found across childhood. This...
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Increased basolateral amygdala metabolic activity during flavor familiarization: an experimental study
BackgroundNovel flavors elicit a cautious neophobic response which is attenuated as the flavor becomes familiar and safe. The attenuation of...
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Sex-differences in proteasome-dependent K48-polyubiquitin signaling in the amygdala are developmentally regulated in rats
BackgroundSex differences have been observed in several brain regions for the molecular mechanisms involved in baseline (resting) and memory-related...
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Transcriptionally defined amygdala subpopulations play distinct roles in innate social behaviors
Social behaviors are innate and supported by dedicated neural circuits, but the molecular identities of these circuits and how they are established...
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Smaller amygdala subnuclei volume in schizophrenia patients with violent behaviors
To investigate the association between the volume of amygdala subnuclei and violent behaviors in patients with schizophrenia (SCZ). In the present...
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Reactivity of the ventromedial prefrontal cortex, but not the amygdala, to negative emotion faces predicts greed personality trait
This study explored whether amygdala reactivity predicted the greed personality trait (GPT) using both task-based and resting-state functional...
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Activation of the CXCR4 Receptor by Chemokine CXCL12 Increases the Excitability of Neurons in the Rat Central Amygdala
Primarily regarded as immune proteins, chemokines are emerging as a family of molecules serving neuromodulatory functions in the develo** and adult...
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Induction of Anxiety-Like Phenotypes by Knockdown of Cannabinoid Type-1 Receptors in the Amygdala of Marmosets
The amygdala is an important hub for regulating emotions and is involved in the pathophysiology of many mental diseases, such as depression and...
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Amygdala-Targeted Relief of Neuropathic Pain: Efficacy of Repetitive Transcranial Magnetic Stimulation in NLRP3 Pathway Suppression
This study investigates the effectiveness of repetitive transcranial magnetic stimulation (rTMS) as a nonpharmacological approach to treating...
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A molecularly defined amygdala-independent tetra-synaptic forebrain-to-hindbrain pathway for odor-driven innate fear and anxiety
Fear-related disorders (for example, phobias and anxiety) cause a substantial public health problem. To date, studies of the neural basis of fear...
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Interleukin-6 is correlated with amygdala volume and depression severity in adolescents and young adults with first-episode major depressive disorder
Inflammatory mechanisms may play crucial roles in the pathophysiology of major depressive disorder (MDD), and cytokine concentrations are correlated...
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Association between salivary oxytocin levels and the amygdala and hippocampal volumes
Salivary oxytocin levels have been widely measured and studied in relation to social behavior because of procedural simplicity and noninvasiveness....
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Proteomic Analysis of the Amygdala Reveals Dynamic Changes in Glutamate Transporter-1 During Progression of Complete Freund’s Adjuvant-Induced Pain Aversion
Pain sufferer usually show an aversion to the environment associated with pain, identified as pain aversion. The amygdala, an almond-shaped limbic...
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Therapeutic effect of Thymoquinone on behavioural response to UCMS and neuroinflammation in hippocampus and amygdala in BALB/c mice model
RationaleMajor depressive disorder is the leading cause of disability worldwide. The corticolimbic system plays a critical role in the emotional and...
