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Prevalence of 13 polyomaviruses in actinic keratosis and matched healthy skin samples of immunocompetent individuals
BackgroundActinic keratosis (AK) is a precursor of cutaneous squamous cell carcinoma (cSCC). UV radiation is the major risk factor for AK, but...
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Niacinamide: a review on dermal delivery strategies and clinical evidence
Niacinamide, an active form of vitamin B3, is recognised for its significant dermal benefits including skin brightening, anti-ageing properties and...
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The Immunogenetic Aspects of Photodynamic Therapy
Photodynamic therapy (PDT) has become the first-line treatment of actinic keratosis, superficial basal cell carcinoma, and squamous cell carcinoma in...
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Spectrum of malignant and premalignant skin lesions in 505 adult subjects at risk of skin cancers
Patients at risk of skin cancers can develop varying types of cutaneous malignancies. However, some subjects may develop only one type of lesion. In...
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A reinforcement learning model for AI-based decision support in skin cancer
We investigated whether human preferences hold the potential to improve diagnostic artificial intelligence (AI)-based decision support using skin...
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An efficient multi-class classification of skin cancer using optimized vision transformer
Skin cancer is a pervasive and deadly disease, prompting a surge in research efforts towards utilizing computer-based techniques to analyze skin...
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Squamous Cell Carcinoma Predisposition Pathophysiology, Diagnosis, and Treatment
Squamous Cell Carcinoma (SCC) is a prevalent form of skin and oral cancer, characterized by the uncontrolled growth of abnormal squamous cells in the...
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Field Cancerization: A Malignant Transformation
Mutations in a cell is natural, especially in aging cells. However, among all mutated cells, only a certain subset could clonally expand, leading to...
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Seven key hub genes identified by gene co-expression network in cutaneous squamous cell carcinoma
BackgroundCutaneous squamous cell carcinoma (cSCC) often follows actinic keratosis (AK) and is the second most common skin cancer worldwide. To...
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Novel meso-substituted porphyrin derivatives and its potential use in photodynamic therapy of cancer
BackgroundPhotodynamic therapy (PDT) is an anticancer treatment that utilizes the interaction of light and a photosensitiser (PS), promoting tumour...
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YAP1/Piezo1 involve in the dynamic changes of lymphatic vessels in UVR-induced photoaging progress to squamous cell carcinoma
BackgroundUV-induced cutaneous squamous cell carcinoma (cSCC) is one of the most common skin cancers. The constant alterations of the...
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Squamous Cell Carcinoma Predisposition Pathophysiology, Diagnosis, and Treatment
Squamous Cell Carcinoma (SCC) is a prevalent form of skin and oral cancer, characterized by the uncontrolled growth of abnormal squamous cells in the...
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Epigenetics insights from perceived facial aging
Facial aging is the most visible manifestation of aging. People desire to look younger than others of the same chronological age. Hence, perceived...
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Skin Cancer: An Overview
Skin cancer is one of the most prevalent forms of cancer, comprising two major types: non-melanoma and melanoma. The major cause behind development...
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Risk Factors of Oral Cancer: Identification and Mechanism of Prevention
Background: Oral cancer is a serious public health problem. Unfortunately, most cases are diagnosed in advanced stages and consequently have a poor...
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Recent Update on Nanoemulsion Impregnated Hydrogel: a Gleam into the Revolutionary Strategy for Diffusion-Controlled Delivery of Therapeutics
Since earlier times, dermatological remedies have been utilized to treat diseases associated with pain, irritation, and skin conditions. Compared to...
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Skin Cancer: An Overview
Skin cancer is one of the most prevalent forms of cancer, comprising two major types: non-melanoma and melanoma. The major cause behind development...
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Large scale clinical exome sequencing uncovers the scope and severity of skin disorders associated with MC1R genetic variants
PurposeGenetic variation in MC1R is a main determinant of red hair color (RHC) phenotype and confers susceptibility to skin disorders.
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Histopathological Basis for Acupuncture
Acupuncture and related techniques involve physical stimulation of cutaneous tissues and cells, but the specific tissue targets of acupuncture and...
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Advances in Photodynamic Therapy Protocols for Nonmelanoma Skin Cancer
Even though most nonmelanoma skin cancer (NMSC) lesions can be successfully treated with surgical removal, the high incidence of this type of cancer...