Search
Search Results
-
New SNP variants of MARVELD2 (DFNB49) associated with non-syndromic hearing loss in Chinese population
中文概要 目 的探究 MARVELD2 在**非综合征耳聋 (NSHL) 人群中的突变频谱和突变频率。
创新点发现 MARVELD2 突变频谱具有明显种族特异性。 ** NSHL 人群中的突变位点及频率不同于已报道的其他人群, 并首次筛选到新致聋候选突变 MARVELD2 c.730G>A。...
-
Detection of human papillomavirus in oropharyngeal squamous cell carcinoma
Worldwide there has been a significant increase in the incidence of oropharyngeal squamous cell carcinoma (OPSCC) etiologically attributed to...
-
Highly sensitive serological approaches for Pepino mosaic virus detection
Pepino mosaic virus (PepMV) causes severe disease in tomato and other Solanaceous crops around globe. To effectively study and manage this viral...
-
Pathogenicity of an FAdV-4 isolate to chickens and its genomic analysis
Fowl adenovirus serotype 4 (FAdV-4) strain SD1511 was isolated from chickens with severe inclusion body hepatitis and hydropericardium syndrome in...
-
Novel ACADVL variants resulting in mitochondrial defects in long-chain acyl-CoA dehydrogenase deficiency
The pathogenesis of very-long-chain acyl-CoA dehydrogenase (VLCAD) deficiency is highly heterogeneous and still unclear. Additional novel variants...
-
Comparative transcriptomic analysis of vascular endothelial cells after hypoxia/re-oxygenation induction based on microarray technology
ObjectiveTo provide comprehensive data to understand mechanisms of vascular endothelial cell (VEC) response to hypoxia/re-oxygenation.
... -
Lung macrophages are involved in lung injury secondary to repetitive diving
This study aimed to establish an animal model of decompression-induced lung injury (DILI) secondary to repetitive diving in mice and explore the role...
-
Regulatory mechanisms and therapeutic potential of microglial inhibitors in neuropathic pain and morphine tolerance
Microglia are important cells involved in the regulation of neuropathic pain (NPP) and morphine tolerance. Information on their plasticity and...
-
Cell models and drug discovery for mitochondrial diseases
Mitochondrion is a semi-autonomous organelle, important for cell energy metabolism, apoptosis, the production of reactive oxygen species (ROS), and Ca
-
Cerebrospinal fluid otorrhea secondary to congenital inner ear dysplasia: diagnosis and management of 18 cases
ObjectiveTo describe the characteristics of the clinical presentation, diagnosis, surgical methods, and outcomes of patients with otogenic...
-
Development of a colloidal gold-based immunochromatographic strip for rapid detection of Rice stripe virus
Rice stripe virus (RSV) causes dramatic losses in rice production worldwide. In this study, two monoclonal antibodies (MAbs) 16E6 and 11C1 against...
-
Preliminary study on the role of novel LysR family gene kp05372 in Klebsiella pneumoniae of forest musk deer
LysR-type transcriptional regulators are involved in the regulation of numerous cellular metabolic processes in Klebsiella pneumoniae , leading to...
-
Systematic review and meta-analysis of the efficacy and safety of immunosuppressive pulse therapy in the treatment of paraquat poisoning
Paraquat (PQ), a highly effective herbicide, is widely used worldwide. PQ poisoning can cause multiple organ failure, in which the lung is the...
-
Comprehensive genetic diagnosis of patients with Duchenne/Becker muscular dystrophy (DMD/BMD) and pathogenicity analysis of splice site variants in the DMD gene
Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are caused by mutations in the DMD gene. The aim of this study is to identify...
-
Antepenultimate residue at the C-terminus of NADPH oxidase RBOHD is critical for its function in the production of reactive oxygen species in Arabidopsis
Production of reactive oxygen species (ROS) is a conserved immune response primarily mediated by NADPH oxidases (NOXs), also known in plants as...