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Botulinum Toxin Treatment in Multiple Sclerosis
According to the latest data from the National Multiple Sclerosis Society (2019) nearly one million people live in US with this disease annually. The... -
Causal relationship between multiple sclerosis and cortical structure: a Mendelian randomization study
BackgroundObservational studies have suggested an association between multiple sclerosis (MS) and cortical structure, but the results have been...
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Ataxia in Multiple Sclerosis
It is well known that the cerebellum is commonly affected in patients with multiple sclerosis (MS), thus making everyday life activities such as... -
Multiple Sclerosis
Almost 200 years since it was first described, multiple sclerosis (MS) remains one of the most intriguing human diseases, with a complexity of... -
Active Induction of a Multiple Sclerosis-Like Disease in Common Laboratory Mouse Strains
Experimental autoimmune encephalomyelitis (EAE) is a neuroinflammatory disease with facets in common with multiple sclerosis (MS). It is induced in... -
Interhemispheric inhibition and gait adaptation associations in people with multiple sclerosis
BackgroundMultiple sclerosis is a neurodegenerative disease that damages the myelin sheath within the central nervous system. Axonal demyelination,...
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Sleep Disorders in Multiple Sclerosis
Multiple sclerosis (MS) is the most common chronic inflammatory demyelinating disease of the central nervous system. Along with a variety of motor... -
Neuropathic Pain in Multiple Sclerosis Patients
Among a multitude of pain syndromes (PS) of diverse locations and types of pathogenesis encountered in multiple sclerosis (MS) patients, most...
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Extracellular Purine Metabolism—Potential Target in Multiple Sclerosis
The purinergic signaling system comprises a complex network of extracellular purines and purine-metabolizing ectoenzymes, nucleotide and nucleoside...
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Evidence for the differential efficacy of yaw and pitch gaze stabilization mechanisms in people with multiple sclerosis
People with multiple sclerosis (PwMS) who report dizziness often have gaze instability due to vestibulo-ocular reflex (VOR) deficiencies and...
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Analysis of Differential TLR Activation in a Mouse Model of Multiple Sclerosis
Multiple sclerosis (MS) is a neurodegenerative and autoimmune disease affecting the central nervous system (CNS). The precise etiology of MS is still... -
Visual imaging as a predictor of neurodegeneration in experimental autoimmune demyelination and multiple sclerosis
Thalamic volume is associated with clinical disability in multiple sclerosis (MS) and is vulnerable to secondary neurodegeneration due to its...
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Interleukin-9 protects from microglia- and TNF-mediated synaptotoxicity in experimental multiple sclerosis
BackgroundMultiple sclerosis (MS) is a progressive neurodegenerative disease of the central nervous system characterized by inflammation-driven...
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Quantitative Meta-analyses of Cognitive Abilities in Children With Pediatric-onset Multiple Sclerosis
Pediatric-onset multiple sclerosis (POMS), is the manifestation of multiple sclerosis in individuals before 18 years of age. About a third of...
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Frontal-striatal glucose metabolism and fatigue in patients with multiple sclerosis, long COVID, and COVID-19 recovered controls
This study compared brain glucose metabolism using FDG-PET in the caudate nucleus, putamen, globus pallidus, thalamus, and dorsolateral prefrontal...
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Effects of the powerball® system on muscle strength, coordination, fatigue, functionality and quality of life in people with multiple sclerosis. A randomized clinical trial
IntroductionAlthough clinical and functional impairments in the lower limbs have been extensively studied in patients with MS, the upper limb (UL)...
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Visual oscillation effects on dynamic balance control in people with multiple sclerosis
BackgroundPeople with multiple sclerosis (PwMS) have balance deficits while ambulating through environments that contain moving objects or visual...
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Drug Delivery Strategies in Multiple Sclerosis, Huntington’s Disease and Other Neurodegenerative Diseases
In healthy individuals, the blood–brain barrier (BBB) protects the brain by obstructing tiny harmful substances in the blood only by hindering the... -
Conversion of Astrocyte Cell Lines to Oligodendrocyte Progenitor Cells Using Small Molecules and Transplantation to Animal Model of Multiple Sclerosis
Astrocytes, the most prevalent cells in the central nervous system (CNS), can be transformed into neurons and oligodendrocyte progenitor cells (OPCs)...
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An Update on the Measurement of Motor Cerebellar Dysfunction in Multiple Sclerosis
Multiple sclerosis (MS) is a progressive disease that often affects the cerebellum. It is characterised by demyelination, inflammation, and...