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Clinical and Experimental Study on Acupuncture for Children with Cerebral Palsy
Cerebral palsy is a group of persistent central motor and posture development disorders and unified use of activity limit syndrome, which is caused...
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Clinical and molecular features of NDM-producing Acinetobacter baumannii in a multicenter study in Israel
BackgroundNDM-producing Acinetobacter baumannii (NDMAb) were reported sporadically worldwide but little is known about the transmission,...
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Clinical Assessment of Brain Disorders
The clinical evaluation of brain diseases strictly depends on patient’s complaint and observation of their behavior. The specialist, often the...
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Clinical characteristics and long-term neurodevelopmental outcomes of leukomalacia in preterm infants and term infants: a cohort study
BackgroundLeukomalacia is a serious form of neonatal brain injury that often leads to neurodevelopmental impairment, and studies on neonatal...
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Minor salivary gland stem cells: a comparative study of the biological properties under clinical-grade culture conditions
Development of clinical-grade, cell preparations is central to cGMP (good manufacturing practice compliant) conditions. This study aimed to...
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Direct oral anticoagulants and the risk of adverse clinical outcomes among patients with different body weight categories: a large hospital-based study
ObjectiveThrough predictable pharmacokinetics—including a convenient fixed-dose regimen, direct oral anticoagulants (DOACs) are preferred over...
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Role of Artificial Intelligence in Clinical and Hospital Pharmacy
Artificial intelligence (AI) has emerged as an influential force in various industries, with potentially revolutionary implications for healthcare....
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Clinical perspectives and outcomes of the giant breast phyllodes tumor and sarcoma: a real-world retrospective study
BackgroundGiant breast malignant phyllodes tumor or sarcoma (GBPS) are rare entities with diameter larger than 10 cm and variously histological...
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Relationship Between Serum Ustekinumab Trough Concentration and Clinical and Biochemical Disease Activity: A Real-World Study in Adult Patients with Crohn’s Disease
Background and ObjectivesThe role of therapeutic drug monitoring for ustekinumab in the treatment of Crohn’s disease has not been defined. This study...
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Estimation of kinetic parameters in dynamic FDG PET imaging based on shortened protocols: a virtual clinical study
This study investigated the estimation of kinetic parameters and production of related parametric K i images in FDG PET imaging using the proposed...
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Clinical characteristics of peripherally inserted central catheter-related complications in cancer patients undergoing chemotherapy: a prospective and observational study
PurposeThe incidence of peripherally inserted central catheter (PICC)-related complications is higher in cancer patients than in noncancer patients....
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Clinical Neuroinnovation: Ethical Frameworks and Emerging Issues
This chapter summarizes complementary prescriptive, principles-based, and empirical (descriptive) ethics approaches in research and treatment of...
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Correlation of toxicities and efficacies of pemetrexed with clinical factors and single-nucleotide polymorphisms: a prospective observational study
BackgroundPemetrexed is an efficacious multi-targeted antifolate with acceptable toxicity for non-squamous non-small cell lung cancer (non-Sq NSCLC)...
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Clinical impact of panel gene sequencing on therapy of advanced cancers of the digestive system: a retrospective, single center study
BackgroundPanel gene sequencing is an established diagnostic tool for precision oncology of solid tumors, but its utility for the treatment of...
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Clinical, pathological, and comprehensive molecular analysis of the uterine clear cell carcinoma: a retrospective national study from TMRG and GINECO network
BackgroundUterine clear cell carcinomas (CCC) represent less than 5% of uterine cancers. Their biological characteristics and clinical management...
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Emerging Pro-neurogenic Therapeutic Strategies for Neurodegenerative Diseases: A Review of Pre-clinical and Clinical Research
The neuroscience community has largely accepted the notion that functional neurons can be generated from neural stem cells in the adult brain,...
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Effect of Capsaicin on 3-NP-Induced Neurotoxicity: A Pre-Clinical Study
The study objectives are to investigate the ability of capsaicin to revert the toxic effects in glutamate and lipopolysaccharide (LPS)-induced...
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Pre-operative vs. post-operative stereotactic radiosurgery for operative metastatic brain tumors: study protocol for a phase III clinical trial
Background and ObjectivesAlmost one third of cancer patients in the United States will develop brain metastases on an annual basis. Surgical...
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PET Imaging in Clinical Oncology
PET/CT imaging has been applied to a variety of physiologic processes and disease states. However, this technology has arguably made its greatest...
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Metformin in therapeutic applications in human diseases: its mechanism of action and clinical study
Metformin, a biguanide drug, is the most commonly used first-line medication for type 2 diabetes mellites due to its outstanding glucose-lowering...
