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Survival benefit of platinum-based regimen in early stage triple negative breast cancer: A meta-analysis of randomized controlled trials
Platinum (Pt)-based chemo-regimens have been proved effective in neoadjuvant and salvage chemotherapy of triple negative breast cancer (TNBC)....
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Development and validation of a nomogram for predicting overall survival in patients with early-onset endometrial cancer
BackgroundThis study aimed to investigate the differences in the clinicopathological characteristics of younger and older patients with endometrial...
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B-cells and regulatory T-cells in the microenvironment of HER2+ breast cancer are associated with decreased survival: a real-world analysis of women with HER2+ metastatic breast cancer
BackgroundDespite major improvements in treatment of HER2-positive metastatic breast cancer (MBC), only few patients achieve complete remission and...
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Analysis of gene expression levels and their impact on survival in 31 cancer-types patients identifies novel prognostic markers and suggests unexplored immunotherapy treatment options in a wide range of malignancies
BackgroundImmunotherapy has dramatically improved cancer treatment by inhibiting or activating specific cell receptors, thus unleashing the host...
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High NANOG expression correlates with worse patients’ survival in esophageal adenocarcinoma
BackgroundPatients diagnosed with esophageal cancer demonstrate a low overall survival even despite the established multimodal therapy as the current...
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Cervical cancer survival prediction by machine learning algorithms: a systematic review
BackgroundCervical cancer is a common malignant tumor of the female reproductive system and is considered a leading cause of mortality in women...
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Melanoma and CLL co-occurrence and survival: role of KC history
BackgroundSurvival following melanoma and chronic lymphocytic leukemia (CLL) have both been individually associated with previous history of...
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“Moderate” adjuvant chemotherapy-induced leukopenia is beneficial for survival of patients with early breast cancer: a retrospective study
BackgroundThe association between chemotherapy-induced leukopenia (CIL) and survival for patients with early breast cancer (EBC) is not known. We...
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Pan-cancer analysis of the prognostic and immunological role of SNX29: a potential target for survival and immunotherapy
BackgroundThere is growing evidence that the SNX family is critical for clinical prognosis, immune infiltration and drug sensitivity in many types of...
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Real-world evidence of treatment patterns and survival of metastatic gastric cancer patients in Germany
BackgroundPatients with metastatic gastric cancer (mGC) have poor prognosis. This real-world study aimed to describe treatment regimens and survival...
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Preoperative IL-8 levels as prognostic indicators of overall survival: an extended follow-up in a prospective cohort with colorectal liver metastases
IntroductionCRC with liver metastases is a major contributor to cancer-related mortality. Despite advancements in liver resection techniques, patient...
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Excellent survival in relapsed stage I testicular cancer
BackgroundTwo thirds of patients with germ-cell cancer (GCC) present as clinical stage I (CSI). Following orchiectomy, active surveillance (AS) has...
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Epidemiology and survival outcomes of HIV-associated cervical cancer in Nigeria
IntroductionInvasive cervical cancer (ICC) is an HIV-associated cancer that is preventable and precancerous stages including early ICC stages could...
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Association between pathologic response and survival after neoadjuvant therapy in lung cancer
Neoadjuvant immunotherapy plus chemotherapy improves event-free survival (EFS) and pathologic complete response (0% residual viable tumor (RVT) in...
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Vitamin D status during and after treatment and ovarian cancer survival
PurposeFive-year relative survival for ovarian cancer remains below 50%. Strategies to improve outcomes are needed. Higher serum 25-hydroxyvitamin D...
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mRNA markers for survival prediction in glioblastoma multiforme patients: a systematic review with bioinformatic analyses
BackgroundGlioblastoma multiforme (GBM) is a type of fast-growing brain glioma associated with a very poor prognosis. This study aims to identify key...
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Survival of advanced/recurrent gastrointestinal stromal tumors treated with tyrosine kinase inhibitors in Taiwan: a nationwide registry study
BackgroundMost gastrointestinal stromal tumors (GISTs) harbor c-KIT or PDGFRA mutations. Administration of tyrosine kinase inhibitors (TKIs) has...
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On-treatment derived neutrophil-to-lymphocyte ratio and survival with palbociclib and endocrine treatment: analysis of a multicenter retrospective cohort and the PALOMA-2/3 study with immune correlates
BackgroundCyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors have been established as a standard treatment for hormone receptor (HR)-positive, human...
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Enhanced epithelial-mesenchymal transition signatures are linked with adverse tumor microenvironment, angiogenesis and worse survival in gastric cancer
Epithelial-mesenchymal transition (EMT) is a crucial mechanism that facilitates cancer cell metastasis. Despite its importance, the clinical...
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Prognosis-correlated Systems Involving Characteristic Diagnostic Gene Sets for Survival Analysis on Glioma
As the most prevalent brain tumor, glioma is malignant with poor prognostic outcomes. As a result, it is of great importance to detect biomarkers for...
