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Fall risk classification with posturographic parameters in community-dwelling older adults: a machine learning and explainable artificial intelligence approach
BackgroundComputerized posturography obtained in standing conditions has been applied to classify fall risk for older adults or disease groups....
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Frailty impacts immune responses to Moderna COVID-19 mRNA vaccine in older adults
BackgroundImmune responses to COVID-19 mRNA vaccines have not been well characterized in frail older adults. We postulated that frailty is associated...
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Insomnia complaints correlated with higher risk of cognitive impairment in older adults following stroke: a National Representative Comparison Study
Although associations among insomnia, cognitive impairment, and stroke have been demonstrated, whether insomnia increases the risk of cognitive...
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Integrated cognitive and physical fitness training enhances attention abilities in older adults
Preserving attention abilities is of great concern to older adults who are motivated to maintain their quality of life. Both cognitive and physical...
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Objectively-measured movement behaviors, systemic low-grade inflammation, and plasma neurofilament light chain in older adults: a population-based study
BackgroundEvidence has linked self-reported sedentary behavior (SB) and physical activity (PA) with cognitive impairment; however, the underlying...
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Immunogenicity and safety of quadrivalent influenza vaccine among young and older adults in Tian**, China: implication of immunosenescence as a risk factor
BackgroundOlder adults are more vulnerable to seasonal influenza than younger adults. The immune responses of older persons to the influenza vaccine...
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A Systematic Review of tACS Effects on Cognitive Functioning in Older Adults Across the Healthy to Dementia Spectrum
Transcranial alternating current stimulation (tACS) is a form of noninvasive brain stimulation that has experienced rapid growth within the aging...
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Two-week step-reduction has limited negative effects on physical function and metabolic health in older adults
PurposeThis study determined the effects of a 2-week step-reduction period followed by 4-week exercise rehabilitation on physical function, body...
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Habitual glucosamine use, APOE genotypes, and risk of incident cause-specific dementia in the older population
BackgroundThe relationship of glucosamine use with incident dementia in the older population remains uncertain. We aimed to evaluate the longitudinal...
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Factors for optimizing intervention programs for cognition in older adults: the value of exergames
This review presents factors that could optimize the effectiveness of an intervention program on cognitive health in older adults. Combined,...
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Centenarians, semi and supercentenarians, COVID-19 and Spanish flu: a serological assessment to gain insight into the resilience of older centenarians to COVID-19
BackgroundAlthough it is well known that the older people have been the most susceptible to COVID-19, there are conflicting data on the...
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A Real-Time Neurophysiologic Stress Test for the Aging Brain: Novel Perioperative and ICU Applications of EEG in Older Surgical Patients
As of 2022, individuals age 65 and older represent approximately 10% of the global population [
1 ], and older adults make up more than one third of...
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Dual-task improvement of older adults after treadmill walking combined with blood flow restriction of low occlusion pressure: the effect on the heart–brain axis
ObjectiveThis study explored the impact of one session of low-pressure leg blood flow restriction (BFR) during treadmill walking on dual-task...
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Older Adults with Pre-sarcopenia/Sarcopenia have Increased Gastrocnemius Muscle Activity to Maintain Upright Postural Control at Stance Perturbation
PurposeWith aging, there is a decline in the ability to balance, leading to a predisposition to falls. The study’s aim was to verify the influence of...
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High-intensity walking in midlife is associated with improved memory in physically capable older adults
BackgroundLittle is known about the associations of midlife- and late life-initiated walking with Alzheimer’s disease (AD)-related cognitive decline...
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Characterization of the angular gyrus in an older adult population: a multimodal multilevel approach
The angular gyrus (AG) has been associated with multiple cognitive functions, such as language, spatial and memory functions. Since the AG is thought...
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Epigenetic age acceleration is associated with blood lipid levels in a multi-ancestry sample of older U.S. adults
BackgroundDyslipidemia, which is characterized by an unfavorable lipid profile, is a key risk factor for cardiovascular disease (CVD). Understanding...
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Association of sarcopenia, pre-sarcopenia, and dynapenia with the onset and progression of locomotive syndrome in Japanese older adults: a cross-sectional study
BackgroundSarcopenia commonly occurs in older adults with motor disorders requiring long-term care, and the clinical features of sarcopenia are...
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Increased levels of GM-CSF and CXCL10 and low CD8+ memory stem T Cell count are markers of immunosenescence and severe COVID-19 in older people
BackgroundAgeing leads to altered immune responses, resulting in higher susceptibility to certain infections in the elderly. Immune ageing is a...
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Changes in surrogate markers of intestinal epithelial injury and microbial translocation in young and older men during prolonged occupational heat stress in temperate and hot conditions
PurposeExertional heat stress can cause damage to the intestinal epithelium and disrupt gastrointestinal barrier integrity, leading to microbial...
