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Treatment Regimes in Diabetes and Their Impact on Biomarkers
In our modern society, we are faced with a mismatch between our evolutionary past as a human species and the current challenges arising from a modern...
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Microorganisms in Pathogenesis and Management of Psoriasis
Unraveling the mechanisms by which microbes colonizing psoriasisPsoriasis patients affect IL-17-related mechanism in the cutaneous response of...
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Preoperative IL-8 levels as prognostic indicators of overall survival: an extended follow-up in a prospective cohort with colorectal liver metastases
IntroductionCRC with liver metastases is a major contributor to cancer-related mortality. Despite advancements in liver resection techniques, patient...
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The Interleukin-8 Pathway in Cancer
Interleukin-8 (IL-8), a pro-inflammatory chemotactic cytokine encoded by the CXCL8 gene, is mainly released by macrophages and other immune cells and...
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Proteomic Biomarkers: What They Are and How Type 2 Diabetes Mellitus Has Similarities with Other Diseases
Type 2 diabetes mellitus (T2DM) is the most frequent form of diabetes, characterized by insulin resistance and impaired insulin release. Its...
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Pleural Tuberculosis
Tuberculosis (TB) is the most common etiology behind pleural effusionEffusionPleural in regions where this infection is endemic. The rupture of a...
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Perioperative Levels of IL8 and IL18, but not IL6, are Associated with Nucleus Basalis Magnocellularis Atrophy Three Months after Surgery
Past studies have observed that brain atrophy may accelerate after surgical procedures. Furthermore, an association of systemic inflammation with...
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Immune Cells: Critical Players in Drug Resistance
The chapter explores the complicated relationship between immune cells and cancer drug resistance. The immune cell composition in the tumor...
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Microorganisms in the Pathogenesis and Management of Spondyloarthritis
Spondyloarthritis is an umbrella term for a group of inflammatory diseases of the joints and spine. The group includes ankylosing spondylitis,...
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Immunotherapy for Cutaneous Melanoma
Melanoma is the most aggressive skin cancer whose incidence is increasing in western countries. Among novel treatments, immunotherapy has shown...
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Modulation and Determination of the Status of Inflammasomes in Leishmania-Infected Macrophages
Leishmania, an intra-macrophage kinetoplastid parasite, modulates a vast array of defensive mechanisms of the host macrophages to create a...
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Botulinum Toxin Therapy in Veterinary Medicine
Emerging literature supports that local injection of botulinum toxins can help local pain in animals. In dogs, botulinum toxin injections have been...
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The Potential Effect of Royal Jelly on Biomarkers Related to COVID-19 Infection and Severe Progression
Royal jelly is a yellowish to white gel-like substance that is known as a “superfood” and consumed by queen bees. There are certain compounds in...
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Fungal Enzyme Inhibitors: Potent Repository of Lead Compounds to Curb Cancer
Fungi are considered to be storehouse of novel biologically and structurally diverse compounds with immense therapeutic potential. Novel therapeutic...
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Associations of the circulating levels of cytokines with the risk of myeloproliferative neoplasms: a bidirectional mendelian-randomization study
ObjectiveIn the pathogenesis of myeloproliferative neoplasms (MPN), inflammation plays an important role. However, it is unclear whether there is a...
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Beispiele für entzündliche Immunpathologien
Als Beispiele für entzündliche Immunopathien werden folgende besprochen: Sepsis, Asthma, Diabetes Typ 1, Multiple Sklerose, Rheumatoide Arthritis,...
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The role of Th17 cells: explanation of relationship between periodontitis and COPD?
Periodontitis and chronic obstructive pulmonary disease (COPD) are chronic inflammatory diseases with common risk factors, such as long-term smoking,...
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Frequencies of SARS-CoV-2 Spike Protein-Specific Memory B Cells in Human PBMCs, Quantified by ELISPOT Assay
Vaccination against SARS-CoV-2 with coronavirus vaccines that elicit protective immune responses is critical to the prevention of severe disease and...
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Mutations in Helicobacter pylori infected patients with chronic gastritis, intestinal type of gastric cancer and familial gastric cancer
BackgroundDevelopment of sequential changes of mucous leading to gastric cancer and familial cases of gastric cancer of intestinal type is widely...