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Ten-year retrospect of the investigation of proximal limbs metastasis in cancer: a multi-center study on survival outcome, limb function status and surgical procedures analysis
BackgroundThe aim of study was to evaluate survival outcome and limb function in cancer patients with proximal limbs metastasis. Associated factors...
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Nanoparticle pre-treatment for enhancing the survival and activation of pulmonary macrophage transplant
Despite recent clinical successes of chimeric antigen receptor T cell therapies in treating liquid cancers, many lingering challenges stand in the...
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The effect of sarcopenia and sarcopenic obesity on survival in gastric cancer
BackgroundSarcopenic obesity arises from increased muscle catabolism triggered by inflammation and inactivity. Its significance lies in its role in...
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Treatment patterns of targeted and nontargeted therapies and survival effects in patients with locally advanced head and neck cancer in Taiwan
BackgroundTaiwan’s National Health Insurance has covered targeted therapy, namely cetuximab, for locally advanced head and neck cancers (LAHNC) since...
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Systemic therapy and radiotherapy related complications and subsequent hospitalisation rates: a systematic review
BackgroundHospitalisation resulting from complications of systemic therapy and radiotherapy places a substantial burden on the patient, society, and...
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Machine learning models predict overall survival and progression free survival of non-surgical esophageal cancer patients with chemoradiotherapy based on CT image radiomics signatures
PurposeTo construct machine learning models for predicting progression free survival (PFS) and overall survival (OS) with esophageal squamous cell...
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Survival outcomes following treatment delays among patients with early-stage female cancers: a nationwide study
BackgroundThe coronavirus disease 2019 (COVID-19) severely hindered the timely receipt of health care for patients with cancer, especially female...
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Factors associated with overall survival, progression-free survival and toxicity in patients with small cell lung cancer and thoracic irradiation in a clinical real-world setting
BackgroundSmall-cell lung cancer (SCLC) is a malignant tumor known for its poor prognosis. In addition to chemotherapy and immunotherapy irradiation...
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One year overall survival of wilms tumor cases and its predictors, among children diagnosed at a teaching hospital in South Western Uganda: a retrospective cohort study
BackgroundWilms tumor (WT) is the second most common solid tumor in Africa with both low overall survival (OS) and event-free survival (EFS) rates....
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β-Catenin promotes long-term survival and angiogenesis of peripheral blood mesenchymal stem cells via the Oct4 signaling pathway
Stem cell therapy has been extensively studied to improve heart function following myocardial infarction; however, its therapeutic potency is limited...
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Enhanced epithelial-mesenchymal transition signatures are linked with adverse tumor microenvironment, angiogenesis and worse survival in gastric cancer
Epithelial-mesenchymal transition (EMT) is a crucial mechanism that facilitates cancer cell metastasis. Despite its importance, the clinical...
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Integrated Bioinformatic Analysis Reveals the Oncogenic, Survival, and Prognostic Characteristics of TPX2 in Hepatocellular Carcinoma
Targeting protein for Xenopus kinesin-like protein 2 (TPX2), a well-known mitotic protein, has been linked to carcinogenesis in several cancers. This...
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Primary central nervous system lymphoma high incidence and poor survival in Finnish population-based analysis
BackgroundWe report here the first population-based incidence rates and prognosis of primary central nervous system lymphoma (PCNSL) in Finland.
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Investigating the role of county-level colorectal cancer screening rates on stage at diagnosis of colorectal cancer in rural Georgia
BackgroundTo examine the impact of county-level colorectal cancer (CRC) screening rates on stage at diagnosis of CRC and identify factors associated...
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Cancer-specific survival in patients with cholangiocarcinoma after radical surgery: a Novel, dynamic nomogram based on clinicopathological features and serum markers
BackgroundThis study aims to (1) identify preoperative testing-based characteristics associated with enhanced prognosis and survival for...
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Post-recurrence survival analysis in patients with oligo-recurrence after curative esophagectomy
BackgroundRecurrent esophageal cancer is associated with dismal prognosis. There is no consensus about the role of surgical treatments in patients...
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Real world predictors of response and 24-month survival in high-grade TP53-mutated myeloid neoplasms
Current therapies for high-grade TP53 -mutated myeloid neoplasms (≥10% blasts) do not offer a meaningful survival benefit except allogeneic stem cell...
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Elective nodal irradiation versus involved-field irradiation for stage II–IV cervical esophageal squamous cell carcinoma patients undergoing definitive concurrent chemoradiotherapy: a retrospective propensity study with 8-year survival outcomes
BackgroundDefinitive concurrent chemoradiotherapy (dCCRT) is suggested as the standard treatment for cervical esophageal squamous cell carcinoma...
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Trends in hospitalization and in-hospital mortality rates among patients with lung cancer in Spain between 2010 and 2020
BackgroundLung cancer is the third most frequent tumor and the main cause of death by tumor in Spain. Although the incidence and mortality are still...
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Transglutaminase 2 is associated with adverse colorectal cancer survival and represents a therapeutic target
Molecular markers for predicting prognosis of colorectal cancer (CRC) patients are urgently needed for effective disease management. We reported...
