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Prostate volume analysis in image registration for prostate cancer care: a verification study
Combined magnetic resonance imaging (MRI) and positron emission tomography/computed tomography (PET/CT) may enhance diagnosis, aid surgical planning...
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MRI, CT, and PETSCAN: Engineer’s Perspective
We first discuss historical developments in tomographic imaging used for medical diagnosis. To discuss magnetic resonance imaging, we introduce the... -
Protocol for CHAMPION study: a prospective study of maximal-cytoreductive therapies for patients with de novo metastatic hormone-sensitive prostate cancer who achieve oligopersistent metastases during systemic treatment with apalutamide plus androgen deprivation therapy
BackgroundThe proposed trial is to examine the feasibility of prostate-specific membrane antigen (PSMA) positron emission tomography/computed...
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False negative rate at 18F-FDG PET/CT in para-aortic lymphnode involvement in patients with locally advanced cervical cancer: impact of PET technology
BackgroundThe identification of factors responsible for false negative (FN) rate at 18 F- Fluorodeoxyglucose (FDG) Positron Emission Tomography...
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Diagnostic utility of metabolic parameters on FDG PET/CT for lymph node metastasis in patients with cN2 non-small cell lung cancer
BackgroundThe aim of this study was to assess the diagnostic utility of metabolic parameters on fluorine-18-fluoro-2-deoxy-D-glucose-positron...
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Imaging Techniques in Pharmacological Precision Medicine
Biomedical imaging is a powerful tool for medical diagnostics and personalized medicines. Examples of commonly used imaging modalities include... -
Detection of HER2 expression using 99mTc-NM-02 nanobody in patients with breast cancer: a non-randomized, non-blinded clinical trial
Background99m Tc radiolabeled nanobody NM-02 ( 99m Tc-NM-02) is a novel single photon emission computed tomography (SPECT) probe with a high affinity...
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Quantitative Ultrasound: An Emerging Technology for Detecting, Diagnosing, Imaging, Evaluating, and Monitoring Disease
Ultrasound has been a popular clinical imaging modality for decades. It is a well-established means of displaying the macroscopic anatomy of... -
BATF promotes tumor progression and association with FDG PET-derived parameters in colorectal cancer
PurposeThe purpose of the study was to evaluate the expression and function of basic leucine zipper ATF-like transcription factor ( BATF) in...
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Diagnostic performance of MRI, SPECT, and PET in detecting renal cell carcinoma: a systematic review and meta-analysis
BackgroundRenal cell carcinoma (RCC) is one of the most common malignancies worldwide. Noninvasive imaging techniques, such as magnetic resonance...
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PSMA PET/CT guided intensification of therapy in patients at risk of advanced prostate cancer (PATRON): a pragmatic phase III randomized controlled trial
BackgroundPositron emission tomography targeting the prostate specific membrane antigen (PSMA PET/CT) has demonstrated unparalleled performance as a...
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Imaging at the nexus: how state of the art imaging techniques can enhance our understanding of cancer and fibrosis
Both cancer and fibrosis are diseases involving dysregulation of cell signaling pathways resulting in an altered cellular microenvironment which...
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[11C]metomidate PET-CT versus adrenal vein sampling for diagnosing surgically curable primary aldosteronism: a prospective, within-patient trial
Primary aldosteronism (PA) due to a unilateral aldosterone-producing adenoma is a common cause of hypertension. This can be cured, or greatly...
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Tumor angiogenesis at baseline identified by 18F-Alfatide II PET/CT may predict survival among patients with locally advanced non-small cell lung cancer treated with concurrent chemoradiotherapy
BackgroundThe study investigated the predictive value of tumor angiogenesis observed by 18 F-ALF-NOTA-PRGD2 II (denoted as 18 F-Alfatide II) positron...
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Imaging the Hypoxic Tumor Microenvironment in Cancer Models
In hypoxic condition oxygen supply is disrupted, and it happens in myocardial infarction, stroke, or tumorous growth. If cells in normal tissue lose... -
Effect of stereotactic body radiotherapy on regional metabolic liver function investigated in patients by dynamic [18F]FDGal PET/CT
PurposeStereotactic body radiotherapy (SBRT) is increasingly used for treatment of liver tumors but the effect on metabolic liver function in...
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Characterising 18F-fluciclovine uptake in breast cancer through the use of dynamic PET/CT imaging
Background18 F-fluciclovine is a synthetic amino acid positron emission tomography (PET) radiotracer that is approved for use in prostate cancer. In...
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eIF6 is potential diagnostic and prognostic biomarker that associated with 18F-FDG PET/CT features and immune signatures in esophageal carcinoma
BackgroundAlthough eukaryotic initiation factor 6 (eIF6) is a novel therapeutic target, data on its importance in the development of esophageal...
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Prognostic value of metabolic activity of the psoas muscle evaluated by preoperative 18F-FDG PET-CT in breast cancer: a retrospective cross-sectional study
BackgroundThis study aimed to evaluate the potential of metabolic activity of the psoas muscle measured by 18 F-fluorodeoxyglucose positron emission...