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Machine Learning-Enabled NIR Spectroscopy. Part 3: Hyperparameter by Design (HyD) Based ANN-MLP Optimization, Model Generalizability, and Model Transferability
Data variations, library changes, and poorly tuned hyperparameters can cause failures in data-driven modelling. In such scenarios, model drift, a...
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A Practical Computer Aided Diagnosis System for Breast Ultrasound Classifying Lesions into the ACR BI-RADS Assessment
PurposeIn this paper, we propose an open-source deep learning-based computer-aided diagnosis system for breast ultrasound images based on the Breast...
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A model of feedforward, global, and lateral inhibition in the locust visual system predicts responses to looming stimuli
Detection of looming obstacles is a vital task for both natural and artificial systems. Locusts possess a visual nervous system with an extensively...
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Scaffolded Chondrogenic Spheroid-Engrafted Model
Therapeutic approaches using mesenchymal stem cells (MSCs) for a cartilage regeneration strategy are based on their multipotent differentiation for...
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Leukocyte subtype classification with multi-model fusion
Accurate classification of leukocytes is crucial for the diagnosis of hematologic malignancies, particularly leukemia. However, traditional leukocyte...
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Personalised exercise rehabilitation in cancer survivorship: the percs triage and referral system study protocol
BackgroundTo effectively embed exercise rehabilitation in cancer survivorship care, a co-ordinated system of acute and community exercise...
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Three-stage Dynamic Brain-cognitive Model of Understanding Action Intention Displayed by Human Body Movements
The ability to comprehend the intention conveyed through human body movements is crucial for effective interpersonal interactions. If people can’t...
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Towards a general-purpose foundation model for computational pathology
Quantitative evaluation of tissue images is crucial for computational pathology (CPath) tasks, requiring the objective characterization of...
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An Experimental Model for the Study of Underwater Pressure Waves on the Central Nervous System in Rodents: A Feasibility Study
Underwater blast differs from blast in air. The increased density and viscosity of water relative to air cause injuries to occur almost exclusively...
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Where Top-Down Meets Bottom-Up: Cell-Type Specific Connectivity Map of the Whisker System
Sensorimotor computation integrates bottom-up world state information with top-down knowledge and task goals to form action plans. In the rodent...
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A Novel Mouse Model for Polysynaptic Retrograde Tracing and Rabies Pathological Research
Retrograde tracing is an important method for dissecting neuronal connections and map** neural circuits. Over the past decades, several virus-based...
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A Mouse Model of Sporadic Alzheimer’s Disease with Elements of Major Depression
After olfactory bulbectomy, animals are often used as a model of major depression or sporadic Alzheimer’s disease and, hence, the status of this...
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Standardization of knowledge-based volumetric modulated arc therapy planning with a multi-institution model (broad model) to improve prostate cancer treatment quality
Purpose: To evaluate whether knowledge-based volumetric modulated arc therapy plans for prostate cancer with a multi-institution model (broad model)...
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A deep learning system for predicting time to progression of diabetic retinopathy
Diabetic retinopathy (DR) is the leading cause of preventable blindness worldwide. The risk of DR progression is highly variable among different...
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True Ageing: An Up-to-date Model for Evaluating the Immune Age of the Chinese Population
The pursuit of immortality has always been a long-standing aspiration of humanity. However, with increasing age comes the unexpected onset of aging....
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Organization of the Nervous System
The nervous system consists of various units, including the central nervous system (brain, brainstem, and spinal cord) and the peripheral nervous...
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A novel memristive neuron model and its energy characteristics
The functional neurons are basic building blocks of the nervous system and are responsible for transmitting information between different parts of...
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Prediction model for EBV infection following HLA haploidentical matched hematopoietic stem cell transplantation
AimsAllogeneic hematopoietic stem cell transplantation (allo-HSCT) is an effective treatment for hematological malignancies. However, viral...
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Pharmacokinetic/pharmacodynamic model of a methionine starvation based anti-cancer drug
A new therapeutic approach against cancer is developed by the firm Erytech. This approach is based on starved cancer cells of an amino acid essential...
