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1. Genetic contribution of caspase-8 variants and haplotypes to breast cancer risk and prognosis: a case-control study in Iran

   Purpose

   Multiple genome-wide and candidate-gene association studies have been conducted to search for common risk variants of breast cancer. Recent...

   Fahimeh Afzaljavan, Elham Vahednia, ... Alireza Pasdar in BMC Medical Genomics

   Article Open access 04 April 2023
   

2. High-throughput circular RNA sequencing reveals the profiles of circular RNA in non-cirrhotic hepatocellular carcinoma

   Background

   Liver cirrhosis is a well-known risk factor for hepatocellular carcinoma (HCC). However, some HCC cases can also originate from...

   Hongyu Li, Liangliang Xu, ... Zhijun Zhu in BMC Cancer

   Article Open access 05 August 2022
   

3. Publication Integrity, Authorship, and Misconduct

   Research is an outcome of innate human inquisitiveness and self-driven efforts to know the unknown. The new knowledge and technology generated...

   Subhash C. Lakhotia in The Quintessence of Basic and Clinical Research and Scientific Publishing

   Chapter 2023
   

4. Biological roles of SLC16A1-AS1 lncRNA and its clinical impacts in tumors

   Recent studies have increasingly highlighted the aberrant expression of SLC16A1-AS1 in a variety of tumor types, where it functions as either an...

   Bing Liao, Jialing Wang, ... ** Ouyang in Cancer Cell International

   Article Open access 30 March 2024
   

5. Defective HIV-1 genomes and their potential impact on HIV pathogenesis

   Defective HIV-1 proviruses represent a population of viral genomes that are selected for by immune pressures, and clonally expanded to dominate the...

   Jeffrey Kuniholm, Carolyn Coote, Andrew J. Henderson in Retrovirology

   Article Open access 28 June 2022
   

6. The Use of Saliva for Genetic and Epigenetic Research

   Minimally invasive sampling methods for collecting oral fluids or cells are preferred in genetic research involving children and in large-scale...

   Zsofia Nemoda in Salivary Bioscience

   Chapter 2020
   

7. CircPIAS1 promotes hepatocellular carcinoma progression by inhibiting ferroptosis via the miR-455-3p/NUPR1/FTH1 axis

   Background

   The role of circRNAs in hepatocellular carcinoma (HCC) progression remains unclear. CircPIAS1 (circBase ID: hsa_circ_0007088) was...

   **ao-Yu Zhang, Shan-Shan Li, ... Yi-Fan Lian in Molecular Cancer

   Article Open access 28 May 2024
   

8. Technologies Used for Analysis of Extracellular Vesicle-Omics

   Extracellular vesicles (EVs) are naturally occurring and secreted membrane vesicles that carry proteins, lipids, and RNAs (mRNAs, microRNAs [miRNAs],...

   **ulan Chen, Nali Zhu, ... Fuquan Yang in Extracellular Vesicles

   Chapter 2024
   

9. Targeting the MALAT1 gene with the CRISPR/Cas9 technique in prostate cancer

   Background

   The MALAT1 lncRNA acts as an oncogene in Prostate cancer (PC); thus, it can be severe as a cancer biomarker.

   Methods

   Using bioinformatics...

   Soraya Ahmadi-Balootaki, Abbas Doosti, ... Hamed Reza Goodarzi in Genes and Environment

   Article Open access 26 September 2022
   

10. From Whole Blood to Isolated Pro-Metastasis Immune Cells: An Ex Vivo Approach to Isolate and Manipulate Immune Cells Contributing to Tumor Metastasis

    Immune evasion hallmark has grabbed wide attention in cancer progression on the clinical level. Accordingly, innate and adaptive immune cells...

    Amany Samir, Aya Aly El Khodiry, Hend M. ElTayebi in Metastasis

    Protocol 2021
    

11. A complete telomere-to-telomere assembly of the maize genome

    A complete telomere-to-telomere (T2T) finished genome has been the long pursuit of genomic research. Through generating deep coverage ultralong...

    Jian Chen, Zijian Wang, ... **sheng Lai in Nature Genetics

    Article Open access 15 June 2023
    

12. Polymorphonuclear Neutrophils and Tumors: Friend or Foe?

    Tumor microenvironment (TME) is a dynamic network that apart from tumor cells includes also cells of the immune system, e.g., neutrophils, which are...

    Izabela Szulc-Kielbik, Magdalena Klink in Interaction of Immune and Cancer Cells

    Chapter 2022
    

13. Toward a comprehensive catalog of regulatory elements

    Regulatory elements are the genomic regions that interact with transcription factors to control cell-type-specific gene expression in different...

    Kaili Fan, Edith Pfister, Zhi** Weng in Human Genetics

    Article 19 March 2023
    

14. Analysis of lncRNA sequences: FAM3D-AS1, LINC01230, LINC01315 and LINC01468 in endometrial cancer

    Background

    The analysis of long non-coding RNA (lncRNA) in endometrial cancer is a novel field of science. Although numerous lncRNA sequences have...

    Jan Bieńkiewicz, Hanna Romanowicz, ... Beata Smolarz in BMC Cancer

    Article Open access 29 March 2022
    

15. Silencing of LINE-1 retrotransposons is a selective dependency of myeloid leukemia

    Transposable elements or transposons are major players in genetic variability and genome evolution. Aberrant activation of long interspersed...

    Zhimin Gu, Yuxuan Liu, ... Jian Xu in Nature Genetics

    Article 08 April 2021
    

16. Population genetics: past, present, and future

    We present selected topics of population genetics and molecular phylogeny. As several excellent review articles have been published and generally...

    Atsuko Okazaki, Satoru Yamazaki, ... Jurg Ott in Human Genetics

    Article 18 July 2020

17. lncRNA FOXD2-AS1 promotes hemangioma progression through the miR-324-3p/PDRG1 pathway

    Background

    Long non-coding RNAs (lncRNAs) FOXD2 adjacent opposite strand RNA 1 (FOXD2-AS1) are reported could function as tumor promoter in several...

    Tiancheng Zhao, Jiayu Zhang, ... Yezhou Li in Cancer Cell International

    Article Open access 24 May 2020
    

18. Interpretation of the role of germline and somatic non-coding mutations in cancer: expression and chromatin conformation informed analysis

    Background

    There has been extensive scrutiny of cancer driving mutations within the exome (especially amino acid altering mutations) as these are more...

    Michael Pudjihartono, Jo K. Perry, ... William Schierding in Clinical Epigenetics

    Article Open access 28 September 2022
    

19. Tracing vitamins on the long non-coding lane of the transcriptome: vitamin regulation of LncRNAs

    A major revelation of genome-scale biological studies in the post-genomic era has been that two-thirds of human genes do not encode proteins. The...

    Fatemeh Yazarlou, Fatemeh Alizadeh, ... Soudeh Ghafouri-Fard in Genes & Nutrition

    Article Open access 12 March 2024
    

20. New genes helped acorn barnacles adapt to a sessile lifestyle

    Barnacles are the only sessile lineages among crustaceans, and their sessile life begins with the settlement of swimming larvae (cyprids) and the...

    Zhaofang Han, Zhixuan Wang, ... Danqing Feng in Nature Genetics

    Article 23 April 2024