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A novel protein encoded by circFNDC3B inhibits tumor progression and EMT through regulating Snail in colon cancer
BackgroundColon cancer (CC) is a common malignant cancer. Recently, circFNDC3B was found to exert biological function in multiple cancers. However,...
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Angiostrongylus cantonensis causes cognitive impairments in heavily infected BALB/c and C57BL/6 mice
BackgroundParasitic infections may cause significant effects on behavior, learning, and memory of the host. In the brain of mice heavily infected...
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Receptor tyrosine kinase C-kit promotes a destructive phenotype of FLS in osteoarthritis via intracellular EMT signaling
BackgroundChronic inflammation, mainly derived from fibroblast-like synoviocytes (FLSs), plays a central role in the pathomechanism of osteoarthritis...
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From the discovery of helminths to the discovery of their carcinogenic potential
Cancer involves a major aberration in the normal behaviour of cells, making them divide continuously, which interferes with the normal physiology of...
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The recent introduction of Angiostrongylus cantonensis and its intermediate host Achatina fulica into Guadeloupe detected by phylogenetic analyses
BackgroundAngiostrongylus cantonensis (rat lungworm) is the main pathogen responsible for eosinophilic meningitis in humans. One of its intermediate...
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Paragonimiasis
Clinically, paragonimiasis in humans caused by Paragonimus westermani and nine other species, mimicking pulmonary tuberculosis, creates diagnostic...
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Detection of rat lungworm (Angiostrongylus cantonensis) infection by real-time PCR from the peripheral blood of animals: a preliminary study
Rat lungworm disease or neuroangiostrongyliasis is a cerebral parasitic infection that affects humans and animals alike. Its clinical signs and...
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Severity of Schistosoma haematobium co-infection with malaria in school-children is potentially modulated by host CD14 gene variants
ObjectiveSchistosomiasis remains a chronic disease of global importance, especially in many rural areas of the world where co-infection with Plasmodiu...
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Opisthorchiasis
Opisthorchiasis is a parasitic infestation of the bile duct and gall bladder of humans, commonly caused by the liver flukes Opisthorchis viverrini...
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Phasmarhabditis eagyptiaca n. sp. (Nematoda: Rhabditidae) Isolated from Egyptian Terrestrial Snails and Its Role as Control Bio-agent to Gastropods
IntroductionTo date nineteen nematode species in the genus Phasmarhabditis Andrássy, 1976 recorded and described. This paper describes Phasmarhabditis...
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Exosomal HMGA2 protein from EBV-positive NPC cells destroys vascular endothelial barriers and induces endothelial-to-mesenchymal transition to promote metastasis
Increased vascular permeability facilitates metastasis. Cancer-secreted exosomes are emerging mediators of cancer-host crosstalk. Epstein-Barr virus...
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Efficiency comparison of experimental fosfatriclaben with three commercial fasciolicides in experimentally infected sheep
In this work, we compare and evaluate the efficiency of fosfatriclaben with three commercial fasciolicides in experimentally infected sheep....
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Spatio-temporal variations of emerging sites infested with schistosome-transmitting Oncomelania hupensis in Hunan Province, China, 1949–2016
BackgroundConstant emerging sites infested with Oncomelania hupensis ( O. hupensis) impede the goal realization of eliminating schistosomiasis. The...
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Culture of fecal indicator bacteria from snail intestinal tubes as a tool for assessing the risk of Opisthorchis viverrini infection in Bithynia snail habitat
BackgroundLike many trematodes of human health significance, the carcinogenic liver fluke, Opisthorchis viverrini , is spread via fecal contamination...
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China-Zanzibar Cooperation Project of Schistosomiasis Control: Study Design
Schistosomiasis is a public health problem mostly in Africa. In 2014, World Health Organization (WHO) signed a tripartite memorandum of understanding...
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An overview of qualitative and quantitative platelet abnormalities in schistosomiasis
Schistosomiasis is a neglected tropical disease referring to the infection with blood parasitic trematodes of the genus Schistosoma . It impacts...
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The effect of trematode infection on the markers of oxidative stress in the offspring of the freshwater snail Lymnaea stagnalis
Most invertebrate species exhibit immunological responses that can inactivate and eliminate penetrating parasites. Such immune responses in...
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Potential impact of flooding on schistosomiasis in Poyang Lake regions based on multi-source remote sensing images
BackgroundFlooding is considered to be one of the most important factors contributing to the rebound of Oncomelania hupensis , a small tropical...
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PCSK9 promotes the progression and metastasis of colon cancer cells through regulation of EMT and PI3K/AKT signaling in tumor cells and phenotypic polarization of macrophages
BackgroundProprotein convertase subtilisin/kexin type 9 (PCSK9) is the ninth member of the proprotein convertase family that regulates lipoprotein...
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Physiology
Effective invasion mechanism aids different worms of parasitic nature to set foot in their host body. Different identifying machineries indicate...