Search
Search Results
-
Ceria nanoparticles ameliorate white matter injury after intracerebral hemorrhage: microglia-astrocyte involvement in remyelination
BackgroundIntracerebral hemorrhage (ICH) can induce excessive accumulation of reactive oxygen species (ROS) that may subsequently cause severe white...
-
Long period changes of hippocampal diffusion kurtosis imaging and its correlation with cognitive dysfunction after incomplete cerebral ischemia–reperfusion in rats
This study aims to summarize the changes of functional diffusion kurtosis imaging (DKI) parameters in the bilateral hippocampal CA1 region of the...
-
Increased extracellular fluid is associated with white matter fiber degeneration in CADASIL: in vivo evidence from diffusion magnetic resonance imaging
BackgroundWhite matter hyperintensities (WMHs) are one of the hallmarks of cerebral small vessel disease (CSVD), but the pathological mechanisms...
-
Abnormal white matter microstructure along the thalamus fiber pathways in women with primary dysmenorrhea
Primary dysmenorrhea (PDM) is a cyclic menstrual pain in the absence of pelvic anomalies, and women with PDM have an increased sensitivity to pain...
-
Research progress on the mechanism of curcumin in cerebral ischemia/reperfusion injury: a narrative review
Cerebral ischemia/reperfusion (I/R) injury can result in different levels of cerebral impairment, and in severe cases, death. Curcumin, an essential...
-
Biomarkers of Brain Damage and Inflammation in Patients with Acute Cerebral Ischemia
Objectives. To study the pathogenetic and clinical significance of hypoxic brain damage and inflammatory mediators as factors in the development of...
-
Microglia as the Critical Regulators of Neuroprotection and Functional Recovery in Cerebral Ischemia
Microglial activation is considered as the critical pathogenic event in diverse central nervous system disorders including cerebral ischemia....
-
Topographic patterns of white matter hyperintensities are associated with multimodal neuroimaging biomarkers of Alzheimer’s disease
BackgroundWhite matter hyperintensities (WMH) are frequently found in Alzheimer’s disease (AD). Commonly considered as a marker of cerebrovascular...
-
Silent brain infarcts and white matter lesions in patients with asymptomatic carotid stenosis
The association of carotid atherosclerosis with silent brain infarcts (SBIs) and white matter lesions (WMLs) currently remains unknown. This study...
-
Melatonin Offers Dual-Phase Protection to Brain Vessel Endothelial Cells in Prolonged Cerebral Ischemia-Recanalization Through Ameliorating ER Stress and Resolving Refractory Stress Granule
Ischemic-reperfusion injury limits the time window of recanalization therapy in cerebral acute ischemic stroke (AIS). Brain vessel endothelial cells...
-
Acute ischemia induces spatially and transcriptionally distinct microglial subclusters
BackgroundDamage in the ischemic core and penumbra after stroke affects patient prognosis. Microglia immediately respond to ischemic insult and...
-
Effects of Gallic Acid on Memory Deficits and Electrophysiological Impairments Induced by Cerebral Ischemia/Reperfusion in Rats Following Exposure to Ambient Dust Storm
We aimed to investigate the probable protective effects of gallic acid (GA) on cognitive deficits, hippocampal long term potentiation (LTP)...
-
-
All Three Supersystems—Nervous, Vascular, and Immune—Contribute to the Cortical Infarcts After Subarachnoid Hemorrhage
The recently published DISCHARGE-1 trial supports the observations of earlier autopsy and neuroimaging studies that almost 70% of all focal brain...
-
miR-383-5p Regulated by the Transcription Factor CTCF Affects Neuronal Impairment in Cerebral Ischemia by Mediating Deacetylase HDAC9 Activity
Stroke, the leading cause of long-term disability worldwide, is caused by the blockage or hemorage of cerebral arteries. The resultant cerebral...
-
Transcriptome Sequencing Identifies Potential Biomarker for White Matter Lesions Diagnosis in the Hypertension Population
Hypertension is confirmed to be one of the major risk factors of leukoaraiosis (LA). However, the pathogenesis of LA is not completely understood and...
-
Neurogenesis and Proliferation of Neural Stem/Progenitor Cells Conferred by Artesunate via FOXO3a/p27Kip1 Axis in Mouse Stroke Model
Promoting neurogenesis and proliferation of endogenous neural stem/progenitor cells (NSPCs) is considered a promising strategy for...
-
Heterogeneity of Astrocytes in Grey and White Matter
Astrocytes are a diverse and heterogeneous type of glial cells. The major task of grey and white matter areas in the brain are computation of...
-
Preserving Mitochondrial Structure and Motility Promotes Recovery of White Matter After Ischemia
Stroke significantly affects white matter in the brain by impairing axon function, which results in clinical deficits. Axonal mitochondria are highly...
-
Nanotechnology: A Daydream for Advanced Imaging, Diagnosis, and Therapeutic Approach for Cerebral Ischemia
Cerebral ischemia is one of the many deadly disorders that is caused due to the blocking of blood vasculatures in the brain and causing oxygen...