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Simulation Modeling of Air and Droplet Temperatures in the Human Respiratory Tract for Inhaled Tobacco Products
Respiratory tract dosimetry predictions for inhalation of tobacco product smoke and aerosols are sensitive to the values of the physicochemical...
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Cross-cultural adaptation of the Parental Perceptions of Children’s Exposure to Tobacco Smoke instrument to the Brazilian context
ObjectiveTo perform a cross-cultural adaptation of the Parental Perceptions of Children’s Exposure to Tobacco Smoke (PPE) instrument to the...
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The role of cancer stromal fibroblasts in mediating the effects of tobacco-induced cancer cell growth
Tobacco products cause a variety of cancers, nicotine and carcinogens are two major factors to link the tobacco products and various cancers. The...
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Characterizing alternative and emerging tobacco product transition of use behavior on Twitter
ObjectiveThe objective of this study was to develop an inductive coding approach specific to characterizing user-generated social media conversations...
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A randomised, open-label, cross-over clinical study to evaluate the pharmacokinetic, pharmacodynamic and safety and tolerability profiles of tobacco-free oral nicotine pouches relative to cigarettes
RationaleTobacco harm reduction (THR) involves encouraging adult smokers who would otherwise continue to smoke to transition to less harmful forms of...
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Classic Psychedelics in Addiction Treatment: The Case for Psilocybin in Tobacco Smoking Cessation
This manuscript reviews research suggesting that classic psychedelics (5-HT2A receptor agonists) are effective in treating addictions including... -
Environmental Tobacco Smoke Exposure Estimated Using the SHSES Scale, and Feature Tracking Computed Tomography-Derived Left Ventricular Global Longitudinal Strain in Hypertensive Patients
Aim of the study was to assess the relationship between environmental tobacco smoke (ETS) and computed tomography-derived left ventricular global...
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The tobacco-specific carcinogen NNK induces pulmonary tumorigenesis via nAChR/Src/STAT3-mediated activation of the renin-angiotensin system and IGF-1R signaling
The renin-angiotensin (RA) system has been implicated in lung tumorigenesis without detailed mechanistic elucidation. Here, we demonstrate that...
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Anti-inflammatory effects of recreational marijuana in virally suppressed youth with HIV-1 are reversed by use of tobacco products in combination with marijuana
BackgroundMarijuana’s putative anti-inflammatory properties may benefit HIV-associated comorbidities. How recreational marijuana use affects gene...
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Tobacco and Alternative Nicotine Products and Their Regulation
Nicotine is highly addictive, interacts with particulates and infection in respiratory disease and promotes cancer in the lung and other organs.... -
Tobacco and Alternative Nicotine Products and Their Regulation
Nicotine is highly addictive, interacts with particulates and infection in respiratory disease and promotes cancer in the lung and other organs.... -
Tobacco leaf curl Puer virus: a novel monopartite begomovirus infecting Nicotiana tabacum in China
Begomoviruses (family Geminiviridae ) cause serious diseases in many crops. In this study, we characterized a begomovirus isolated from a tobacco...
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ARID2 suppression promotes tumor progression and upregulates cytokeratin 8, 18 and β-4 integrin expression in TP53-mutated tobacco-related oral cancer and has prognostic implications
Mutations in ARID2 and TP53 genes are found to be implicated in the tobacco related tumorigeneses. However, the effect of loss of ARID2 in the TP53 ...
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Tobacco use in the Myeloproliferative neoplasms: symptom burden, patient opinions, and care
BackgroundPatients with Philadelphia-negative Myeloproliferative Neoplasms (MPN) suffer from numerous symptoms and decreased quality of life. Smoking...
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Ectodomain shedding of proteins important for SARS-CoV-2 pathogenesis in plasma of tobacco cigarette smokers compared to electronic cigarette vapers: a cross-sectional study
The impact of tobacco cigarette (TCIG) smoking and electronic cigarette (ECIG) va** on the risk of development of severe COVID-19 is controversial....
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The effects of tobacco control policies on global smoking prevalence
Substantial global effort has been devoted to curtailing the tobacco epidemic over the past two decades, especially after the adoption of the...
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Genome-wide methylation and expression analyses reveal the epigenetic landscape of immune-related diseases for tobacco smoking
BackgroundSmoking is a major causal risk factor for lung cancer, chronic obstructive pulmonary disease (COPD), cardiovascular disease (CVD), and is...
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A Review of Web-Based Tobacco Control Media Archives for Researchers and Practitioners
Web-based resources for tobacco use prevention and control provide valuable tools for cancer education. This study sought to (a) identify existing...
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The Role of Dopamine D3 Receptors in Tobacco Use Disorder: A Synthesis of the Preclinical and Clinical Literature
Tobacco smoking is a significant cause of preventable morbidity and mortality globally. Current pharmacological approaches to treat tobacco use... -
Sensory gating in tobacco-naïve cannabis users is unaffected by acute nicotine administration
ObjectivesLong-term cannabis use has been associated with the appearance of psychotic symptoms and schizophrenia-like cognitive impairments; however...