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The Role of Cytogenetic Rearrangements in the Formation of Resistance in Relapse of Acute Lymphoblastic Leukemia
AbstractCytogenetic rearrangements were studied in bone marrow cells of 24 patients with relapse of acute lymphoblastic leukemia (ALL). The authors...
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A comparative study on ctDNA and tumor DNA mutations in lung cancer and benign cases with a high number of CTCs and CTECs
BackgroundLiquid biopsy provides a non-invasive approach that enables detecting circulating tumor DNA (ctDNA) and circulating tumor cells (CTCs)...
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Effect of Changes in Genome Ploidy on the Mosaic Character of nptII Gene Expression in Epialleles of the Transgenic Tobacco Line Nu21
AbstractThe influence of changes in the genome ploidy and the gene dose on the mosaic pattern of expression of the npt II gene in epialleles of the...
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Identification of target genes regulated by encystation-induced transcription factor Myb2 using knockout mutagenesis in Giardia lamblia
BackgroundEncystation is one of the two processes comprising the life cycle of Giardia lamblia , a protozoan pathogen with tetraploid genome. Giardia...
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Cytogenetic and Karyotype Study on Hibiscus sabdariffa L. in Indigenous Populations of Iran
AbstractThe main goal of cytogenetic studies on a plant is to provide general information about the evolutionary history of the plant, determine its...
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Aneuploidy during development in facultative parthenogenetic Drosophila
From concatenated chromosomes to polyploidization, large-scale genome changes are known to occur in parthenogenetic animals. Here, we report mosaic...
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Low-dose DNA demethylating therapy induces reprogramming of diverse cancer-related pathways at the single-cell level
BackgroundEpigenetic reprogramming using DNA demethylating drugs is a promising approach for cancer therapy, but its efficacy is highly dependent on...
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Eupolyploidy As a Mode in Plant Speciation
AbstractWhen discussing phenomena of whole genome duplication, the terms “neopolyploid,” “mesopolyploid,” and “paleopolyploid” are used in their...
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Progenitor species hold untapped diversity for potential climate-responsive traits for use in wheat breeding and crop improvement
Climate change will have numerous impacts on crop production worldwide necessitating a broadening of the germplasm base required to source and...
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Basics of Stem Cell Biology as Applied to the Brain
Stem cell technology can allow us to produce human neuronal cell types outside the body, but what exactly are stem cells, and what challenges are...
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Telomere-to-telomere assemblies of 142 strains characterize the genome structural landscape in Saccharomyces cerevisiae
Pangenomes provide access to an accurate representation of the genetic diversity of species, both in terms of sequence polymorphisms and structural...
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Improving Salt Tolerance in Trifolium alexandrinum L. through Interspecific Hybridization, Polyploidization and Induced Variations
AbstractSoil salinity significantly affects crop productivity throughout the world. Improving intrinsic salt tolerance of the plants may effectively...
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Genoty** of Interspecific Brassica rapa Hybrids Implying β-Tubulin Gene Intron Length Polymorphism (TBP/cTBP) Assessment
The Crucifers family (Brassicaceae) includes a large number of economically important crops, particularly Brassica rapa , which is a widely used model...
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Zygotic Autopolyploidization of Rye (Secale cereale L.)
AbstractThe paper presents the results of zygotic autopolyploidization by the nitrous oxide (N 2 O) of diploid cultivars and F 1 hybrids of winter rye....
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Genome-wide identification of endogenous viral sequences in alfalfa (Medicago sativa L.)
Endogenous viral elements (EVEs) have been for the most part described in animals and to a less extent in plants. The endogenization was proposed to...
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Haplotype-resolved genome analyses of a heterozygous diploid potato
Potato ( Solanum tuberosum L.) is the most important tuber crop worldwide. Efforts are underway to transform the crop from a clonally propagated...
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Botany of Coleus forskohlii
The genus Coleus earlier consisted of about 150 species, but many of these have now been transferred to other genera. The species of the Coleus are...
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Exploration of Parascaris species in three different Equus populations in China
BackgroundThe roundworms, Parascaris spp., are important nematode parasites of foals and were historically model organisms in the field of cell...
