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Post-recurrence survival analysis in patients with oligo-recurrence after curative esophagectomy
BackgroundRecurrent esophageal cancer is associated with dismal prognosis. There is no consensus about the role of surgical treatments in patients...
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β-blockers and breast cancer survival by molecular subtypes: a population-based cohort study and meta-analysis
BackgroundThe association between use of β-blockers and breast cancer (BC) prognosis has been investigated in several observational studies, with...
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Improve individual treatment by comparing treatment benefits: cancer artificial intelligence survival analysis system for cervical carcinoma
PurposeThe current study aimed to construct a novel cancer artificial intelligence survival analysis system for predicting the individual mortality...
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Survival outcomes in endometrial cancer patients according to diabetes: a systematic review and meta-analysis
BackgroundDiabetes is an established risk factor for endometrial cancer development but its impact on prognosis is unclear and epidemiological...
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Efficacy-effectiveness analysis on survival in a population-based real-world study of BRAF-mutated metastatic colorectal cancer patients treated with encorafenib-cetuximab
BackgroundEncorafenib-cetuximab has been approved for pretreated BRAF V600E -mutated metastatic colorectal cancer (mCRC) patients based on efficacy...
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Post-diagnosis smoking cessation and survival of patients with head and neck cancer: a systematic review and meta-analysis
Cigarette smoking is the main risk factor for head and neck cancer (HNC) and many HNC patients are active smokers at diagnosis. We conducted a...
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Effect of adjuvant radiotherapy on overall survival and breast cancer-specific survival of patients with malignant phyllodes tumor of the breast in different age groups: a retrospective observational study based on SEER
PurposeMalignant phyllodes tumor of the breast (MPTB) is a rare type of breast cancer, with an incidence of less than 1%. The value of adjuvant...
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Increased FOXJ1 protein expression is associated with improved overall survival in high-grade serous ovarian carcinoma: an Ovarian Tumor Tissue Analysis Consortium Study
BackgroundRecently, we showed a >60% difference in 5-year survival for patients with tubo-ovarian high-grade serous carcinoma (HGSC) when stratified...
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Artificial intelligence-based prognostic model accurately predicts the survival of patients with diffuse large B-cell lymphomas: analysis of a large cohort in China
BackgroundDiffuse large B-cell lymphomas (DLBCLs) display high molecular heterogeneity, but the International Prognostic Index (IPI) considers only...
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The influence of adjuvant chemotherapy dose intensity on overall survival in resected colon cancer: a multicentered retrospective analysis
BackgroundColorectal cancer remains the second leading cause of cancer death in North America. Fluorouracil and oxaliplatin based adjuvant...
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Trastuzumab deruxtecan versus trastuzumab emtansine in HER2-positive metastatic breast cancer: long-term survival analysis of the DESTINY-Breast03 trial
Trastuzumab deruxtecan (T-DXd) demonstrated significantly improved efficacy over trastuzumab emtansine (T-DM1) in DESTINY-Breast03 (median follow-up,...
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Association between concomitant proton pump inhibitor use and survival of patients with metastatic prostate cancer receiving abiraterone acetate: a post-hoc analysis of pooled data from three randomized controlled trials
BackgroundEvidence suggests proton pump inhibitor (PPI) use may attenuate the effect of abiraterone acetate plus prednisone (AAP) in metastatic...
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Genome wide DNA methylation analysis identifies novel molecular subgroups and predicts survival in neuroblastoma
BackgroundNeuroblastoma is the most common malignancy in infancy, accounting for 15% of childhood cancer deaths. Outcome for the high-risk disease...
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CT texture analysis in predicting treatment response and survival in patients with hepatocellular carcinoma treated with transarterial chemoembolization using random forest models
BackgroundUsing texture features derived from contrast-enhanced computed tomography (CT) combined with general imaging features as well as clinical...
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Standardised survival probabilities: a useful and informative tool for reporting regression models for survival data
BackgroundWhen interested in studying the effect of a treatment (or other exposure) on a time-to-event outcome, the most popular approach is to...
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Integrated Bioinformatic Analysis of the Correlation of HOXA10 Expression with Survival and Immune Cell Infiltration in Lower Grade Glioma
Homeobox A10 (HOXA10) encodes a transcription factor that regulates developmental processes. Whether HOXA10 mRNA levels in lower grade glioma (LGG)...
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Analysis of clinical features, genomic landscapes and survival outcomes in HER2-low breast cancer
BackgroundNovel human epidermal growth factor receptor 2 (HER2)-directed antibody–drug conjugates prompt the identification of the HER2-low subtype....
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Architecting the metabolic reprogramming survival risk framework in LUAD through single-cell landscape analysis: three-stage ensemble learning with genetic algorithm optimization
Recent studies have increasingly revealed the connection between metabolic reprogramming and tumor progression. However, the specific impact of...
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Tumour infiltrating lymphocytes and survival after adjuvant chemotherapy in patients with gastric cancer: post-hoc analysis of the CLASSIC trial
BackgroundOnly a subset of gastric cancer (GC) patients with stage II–III benefits from chemotherapy after surgery. Tumour infiltrating lymphocytes...
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Sample average treatment effect on the treated (SATT) analysis using counterfactual explanation identifies BMT and SARS-CoV-2 vaccination as protective risk factors associated with COVID-19 severity and survival in patients with multiple myeloma
Patients with multiple myeloma (MM), an age-dependent neoplasm of antibody-producing plasma cells, have compromised immune systems and might be at...
