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A comprehensive genomic reporting structure for communicating all clinically significant primary and secondary findings
Genomic sequencing (GS) can reveal secondary findings (SFs), findings unrelated to the reason for testing, that can be overwhelming to both patients...
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Current practices for QSP model assessment: an IQ consortium survey
Quantitative Systems Pharmacology (QSP) modeling is increasingly applied in the pharmaceutical industry to influence decision making across a wide...
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Knowledge, attitude and practices of malaria preventive measures among mothers with children under five years in a rural setting of Ghana
BackgroundMalaria remains a major public health concern around the world, particularly in resource-constrained countries. Malaria still accounts for...
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A qualitative study of infection prevention and control practices in the maternal units of two Ghanaian hospitals
IntroductionHealthcare-associated infections (HAIs) remain a common challenge in healthcare delivery, with a significant burden in low- and...
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Patient and provider perspectives on polygenic risk scores: implications for clinical reporting and utilization
BackgroundPolygenic risk scores (PRS), which offer information about genomic risk for common diseases, have been proposed for clinical...
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Development of a clinical polygenic risk score assay and reporting workflow
Implementation of polygenic risk scores (PRS) may improve disease prevention and management but poses several challenges: the construction of...
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Knowledge, attitudes and practices of health care professionals towards adverse drug reaction reporting in public sector primary health care facilities in a South African district
PurposeAdverse drug reactions (ADRs) have an appreciable impact on patients’ health. Little is known however about ADR reporting in ambulatory care...
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A comparative assessment of the community frontline health workers for their knowledge and practices of malaria diagnosis and treatment in three contiguous districts Mandla, Balaghat, and Dindori of Madhya Pradesh, India
BackgroundGlobal malaria cases rose by 14 million, and deaths by 69,000, in 2020. In India, a 46% decline has been reported between 2020 and 2019. In...
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Analysis of attitudes and practices influencing adherence to seasonal malaria chemoprevention in children under 5 years of age in the Dosso Region of Niger
BackgroundSeasonal malaria chemoprevention (SMC) consists of the intermittent administration of a 3 day course of anti-malarial medications during...
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Content Analysis of US FDA Warning Letters Issued to Compounding Pharmacies Regarding Violations of Current Good Manufacturing Practices Between 2017 and 2022
PurposeAssessment of the US FDA-issued WLs content is an educational tool that can be used in the continuous training program of community...
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Current laboratory and clinical practices in reporting and interpreting anti-nuclear antibody indirect immunofluorescence (ANA IIF) patterns: results of an international survey
BackgroundThe International Consensus on Antinuclear Antibody (ANA) Patterns (ICAP) has recently proposed nomenclature in order to harmonize ANA...
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Prevalence of asymptomatic Leishmania infection and knowledge, perceptions, and practices in blood donors in mainland Portugal
BackgroundAsymptomatic infection is the most common outcome of exposure to Leishmania parasites. In the Mediterranean region, where Leishmania...
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Community knowledge, attitude, practices and beliefs associated with persistence of malaria transmission in North-western and Southern regions of Tanzania
BackgroundDespite significant decline in the past two decades, malaria is still a major public health concern in Tanzania; with over 93% of the...
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An observational study of workflows to support fecal testing for colorectal cancer screening in primary care practices serving Medicaid enrollees
Abstract BackgroundScreening supports early detection and treatment of colorectal cancer (CRC). Provision of fecal immunochemical tests/fecal occult...
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Perceptions, attitudes, and practices of a Belgian teaching hospital's physicians, pharmacists, and nurses regarding antibiotic use and resistance: survey towards targeted actions for Antimicrobial Stewardship
ObjectivesThis study aimed to identify barriers to the proper use of antibiotics by healthcare professionals and to help the hospital Antimicrobial...
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The reporting of neuropsychiatric symptoms in electronic health records of individuals with Alzheimer’s disease: a natural language processing study
BackgroundNeuropsychiatric symptoms (NPS) are prevalent in the early clinical stages of Alzheimer’s disease (AD) according to proxy-based...
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Best practices for the development and fit-for-purpose validation of biomarker methods: a conference report
This conference report summarized a full-day workshop, “best practices for the development and fit-for-purpose validation of biomarker methods,”...
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Proton pump inhibitor use: systematic review of global trends and practices
PurposeProton pump inhibitors (PPIs) reduce acid secretion in the stomach and rank as one of the most widely used acid-suppressing medicines...
