Search
Search Results
-
Influenza A Virus Neuraminidase Inhibitors
Depending on the strain, influenza A virus causes animal, zoonotic, pandemic, or seasonal influenza with varying degrees of severity. Two surface...
-
Application of Nanotechnology in Stroke Recovery
Stroke is a devastating condition, for which there is still no effective therapy. Nanotechnology is advanced and advantageous over conventional drug...
-
Pharmacokinetic Comparison of Nine Bioactive Compounds of Guanxinshutong Capsule in Normal and Acute Myocardial Infarction Rats
Background and ObjectivesGuanxinshutong capsules (GXST) are usually used to treat acute myocardial infarction (AMI), and the clinical effect of GXST...
-
Antioxidant System and Endoplasmic Reticulum Stress in Cataracts
The primary underlying contributor for cataract, a leading cause of vision impairment and blindness worldwide, is oxidative stress. Oxidative stress...
-
Interactions Between the Ubiquitin–Proteasome System, Nrf2, and the Cannabinoidome as Protective Strategies to Combat Neurodegeneration: Review on Experimental Evidence
Neurodegenerative disorders are chronic brain diseases that affect humans worldwide. Although many different factors are thought to be involved in...
-
Targeting ferroptosis and ferritinophagy: new targets for cardiovascular diseases
Cardiovascular diseases (CVDs) are a leading factor driving mortality worldwide. Iron, an essential trace mineral, is important in numerous...
-
Recent Advances in Computational Modeling of BACE1 Inhibitors as Anti-Alzheimer Agents
A growing number of people worldwide are being affected by aging-associated neurodegenerative illnesses, the most prevalent of which, Alzheimer’s, is...
-
Iron Metabolism and Ferroptosis in Early Brain Injury after Subarachnoid Haemorrhage
At present, it appears that the prognosis for subarachnoid haemorrhage (SAH), which has a high death and disability rate, cannot be greatly improved...
-
P2X7Rs: new therapeutic targets for osteoporosis
Increasing evidence suggests that both the occurrence and progression of osteoporosis are associated with inflammation, especially in primary...
-
Therapeutic benefits of flavonoids against neuroinflammation: a systematic review
Flavonoids are an important class of natural polyphenolic compounds reported to exert beneficial effects in cardiovascular and metabolic diseases,...
-
Current Updates on Potential Role of Flavonoids in Hypoxia/Reoxygenation Cardiac Injury Model
Clinically, timely reperfusion strategies to re-establish oxygenated blood flow in ischemic heart diseases seem to salvage viable myocardium...
-
Therapeutic Application of Microbial Metabolites in Free Radical Induced Tumorigenesis
Reactive oxygen species (ROS) such as superoxide, hydroxyl radical, and hydrogen peroxide are responsible for the development of tumors by causing...
-
Ferritinophagy and Ferroptosis in Cerebral Ischemia Reperfusion Injury
Cerebral ischemia–reperfusion injury (CIRI) is the second leading cause of death worldwide, posing a huge risk to human life and health. Therefore,...
-
Role of polyphenolic compounds and their nanoformulations: a comprehensive review on cross-talk between chronic kidney and cardiovascular diseases
Chronic kidney disease (CKD) affects a huge portion of the world’s population and frequently leads to cardiovascular diseases (CVDs). It might be...
-
Therapeutic Application of Microbial Metabolites in Free Radical–Induced Tumorigenesis
Reactive oxygen species (ROS) such as superoxide, hydroxyl radical, and hydrogen peroxide are responsible for the development of tumors by causing...
-
Lipid-Based Nanocarriers for the Delivery of Phytoconstituents
Over the last decade, lipid-based nanocarriers have proven to be a good carrier for many pharmaceutical medications. Different types of lipid-based...
-
Bioactive compounds as potential angiotensin-converting enzyme II inhibitors against COVID-19: a sco** review
Objective and designThe current study aimed to summarize the evidence of compounds contained in plant species with the ability to block the...
-
Research progress on the mechanism of anti-myocardial infarction effect and clinical application of effective components of Salvia miltiorrhiza
Salvia miltiorrhiza , a plant in the Labiatae family, is a traditional Chinese herb. The small molecular components in S. miltiorrhiza can be divided...
-
Transcellular Transport Behavior of the Intact Polymeric Mixed Micelles with Different Polymeric Ratios
In order to better promote the application of the polymeric mixed micelles (PMMs) in oral delivery, in addition to focusing on the improvement of...
-
Dendrimers-Mediated Delivery of Phytoconstituents
The potential for dendrimers, highly branching three-dimensional macromolecules, to function as drug delivery vehicles has been extensively...