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Biomechanical Remodeling of Aortic Valve Interstitial Cells During Calcified Lesion Formation In Vitro
Healthy aortic heart valves are essential to the regulation of unidirectional blood flow. Calcific aortic valve disease (CAVD) is an actively...
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Screening and diagnosis of cardiovascular disease using artificial intelligence-enabled cardiac magnetic resonance imaging
Cardiac magnetic resonance imaging (CMR) is the gold standard for cardiac function assessment and plays a crucial role in diagnosing cardiovascular...
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Ultrasound of the Heart
The primary role of the cardiovascular system is to pump blood throughout the body to provide oxygen and essential life-sustaining nutrients to all...
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Interstitial Edema of the Interatrial Septum in Patients with Atrial Fibrillation and Chronic Heart Failure
We studied the presence of interstitial edema of the interatrial septum in patients with chronic heart failure (CHF) with atrial fibrillation ( n= 23)...
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Screening of immune-related secretory proteins linking chronic kidney disease with calcific aortic valve disease based on comprehensive bioinformatics analysis and machine learning
BackgroundChronic kidney disease (CKD) is one of the most significant cardiovascular risk factors, playing vital roles in various cardiovascular...
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Aortic disease and cardiomyopathy in patients with a novel DNMT3A gene variant causing Tatton-Brown–Rahman syndrome
Tatton-Brown–Rahman syndrome (TBRS) is a rare congenital genetic disorder caused by autosomal dominant pathogenic variants in the DNA...
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Plasma fibroblast activation protein is decreased in acute heart failure despite cardiac tissue upregulation
BackgroundCardiac fibroblast activation protein (FAP) has an emerging role in heart failure (HF). A paradoxical reduction in its levels in...
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Utilization of triple antithrombotic therapy in patients with atrial fibrillation undergoing percutaneous coronary intervention
BackgroundTriple antithrombotic therapy (TAT), a combination of an oral anticoagulant and dual antiplatelet therapy (DAPT), is a key treatment for...
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Genomic approaches to identify and investigate genes associated with atrial fibrillation and heart failure susceptibility
Atrial fibrillation (AF) and heart failure (HF) contribute to about 45% of all cardiovascular disease (CVD) deaths in the USA and around the globe....
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Fluid Mechanics of Fetal Left Ventricle During Aortic Stenosis with Evolving Hypoplastic Left Heart Syndrome
In cases of fetal aortic stenosis and evolving Hypoplastic Left Heart Syndrome (feHLHS), aortic stenosis is associated with specific abnormalities...
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DNA methylation abnormalities of imprinted genes in congenital heart disease: a pilot study
BackgroundCongenital heart disease (CHD) is resulted from the interaction of genetic aberration and environmental factors. Imprinted genes, which are...
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Preclinical Models of Cardiac Disease: A Comprehensive Overview for Clinical Scientists
For recent decades, cardiac diseases have been the leading cause of death and morbidity worldwide. Despite significant achievements in their...
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The Role of the Oxidative Stress-Inflammation Axis in the COVID-19-Infected Patients with Chagas Disease: A Key Parameter To Be Considered During the Pandemic
Purpose of ReviewThe global COVID-19 pandemic has become a major public health problem since December 2019, affecting millions of people, especially...
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miR194 hypomethylation regulates coronary artery disease pathogenesis
Coronary artery disease (CAD) is one of the most common heart diseases, characterized by the hardening and narrowing of arteries, resisting blood...
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Serotonin and Cardiac Valves Degeneration in Dog
Chronic valvular heart disease, with myxomatous degeneration and thickening of the mitral valve leaflets, is the most common heart disease in dogs....
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The efficacy and safety of direct oral anticoagulants versus vitamin K antagonists in patients with left-sided bioprosthetic heart valves and atrial fibrillation: a systematic review and meta-analysis
BackgroundThe efficacy and safety of direct oral anticoagulants (DOACs) versus vitamin K antagonists (VKAs) for the treatment of patients with...
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The SGLT2 inhibitor empagliflozin in patients hospitalized for acute heart failure: a multinational randomized trial
The sodium–glucose cotransporter 2 inhibitor empagliflozin reduces the risk of cardiovascular death or heart failure hospitalization in patients with...
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Loss of ADAMTS19 causes progressive non-syndromic heart valve disease
Valvular heart disease is observed in approximately 2% of the general population
1 . Although the initial observation is often localized (for example,...
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Association between induction of the self-management system for preventing readmission and disease severity and length of readmission in patients with heart failure
ObjectiveWe recently developed the self-management system using the HF points and instructions to visit hospitals or clinics when the points exceed...
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Controlling the Flow Separation in Heart Valves Using Vortex Generators
A comprehensive computational study is performed to investigate the effectiveness of vortex generators (VGs) applied to mechanical bi-leaflet heart...
