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Expression of angiogenic markers in jawbones and femur in a rat model treated with zoledronic acid
ObjectivesThis study aimed to investigate the gene expression of angiogenic marker in surgically treated jawbones and femur on a rat model...
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Transdermal Permeation of Caffeine Aided by Ionic Liquids: Potential for Enhanced Treatment of Cellulite
Ginoid hydrolipodystrophy (HDLG) or “cellulite” involves alteration of the cutaneous relief and occurs in 80-90% of the female population. Several...
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The biphasic activity of autophagy and heat shock protein response in peripheral blood mononuclear cells following acute resistance exercise in resistance-trained males
PurposeAutophagy and heat shock protein (HSP) response are proteostatic systems involved in the acute and adaptive responses to exercise. These...
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Passive muscle stiffness is correlated with the intramuscular adipose tissue in young individuals
PurposeWe investigated the relationship between intramuscular adipose tissue (IntraMAT) and muscle stiffness (passive and mechanical) and lengthening...
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An RNA-sequencing transcriptome of the rodent Schwann cell response to peripheral nerve injury
BackgroundThe important contribution of glia to mechanisms of injury and repair of the nervous system is increasingly recognized. In stark contrast...
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Microneurography: Recordings from Single Neurons in Human Peripheral Nerves
Over the last 50 years, the technique of microneurography has provided us with valuable insights into activity in human nerves. Microneurography...
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Acetyl-CoA synthetase 2 contributes to a better prognosis for liver cancer by switching acetate-glucose metabolism
Acetyl-CoA synthetase 2 (ACSS2)-dependent acetate usage has generally been associated with tumorigenesis and increased malignancy in cancers under...
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A H3K27M-targeted vaccine in adults with diffuse midline glioma
Substitution of lysine 27 to methionine in histone H3 (H3K27M) defines an aggressive subtype of diffuse glioma. Previous studies have shown that a...
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Subcutaneous Xenograft Models for Studying PDT In Vivo
The most facile, reproducible, and robust in vivo models for evaluating the anticancer efficacy of photodynamic therapy (PDT) are subcutaneous...
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Imaging Modalities in the Detection and Diagnosis of Metastatic Disease
Imaging is a critical tool in the evaluation and workup of patients with known or suspected metastatic disease and in the follow-up of disease...
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rVSV-ΔG-SARS-CoV-2-S vaccine: repeated intramuscular (IM) toxicity, local tolerance, immunogenicity and biodistribution study in NZW rabbits
BriLife ® , a vector-based vaccine that utilizes the recombinant vesicular stomatitis virus (VSV) platform to express and present the spike antigen of...
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Cerebrovascular function and its association with systemic artery function and stiffness in older adults with and without mild cognitive impairment
PurposeOur aim was to compare cerebrovascular and systemic vascular function between older adults with and without mild cognitive impairment (MCI),...
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Which Analysis Approach Is Adequate to Leverage Clinical Microdialysis Data? A Quantitative Comparison to Investigate Exposure and Response Exemplified by Levofloxacin
PurposeSystematic comparison of analysis methods of clinical microdialysis data for impact on target-site drug exposure and response.
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Arterial stiffness and augmentation index are associated with balance function in young adults
ObjectiveArterial stiffness and pulsatile central hemodynamics have been shown to affect various aspects of physical function, such as exercise...
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Two-component vaccine consisting of virus-like particles displaying hepatitis C virus envelope protein 2 oligomers
Development of B-cell-based hepatitis C virus (HCV) vaccines that induce broadly neutralizing antibodies (bNAbs) is hindered by extensive sequence...
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Quantification of Upper Limb Movements in Patients with Hereditary or Idiopathic Ataxia
Assessment of ataxic movements is usually based on clinical judgment. Technical devices can be employed in the quantification of ataxic movements in...
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Introduction to Musculoskeletal System
Human life and sports are inseparable from the coordinated work of bones and muscles. For example, muscles pull bones to produce movement, and the...
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An Imminence to Humans and Animals: The Rift Valley Fever Virus
Rift Valley Fever (RVF) is an acute viral hemorrhagic fever caused by an arbovirus Rift Valley Fever Virus (RVFV) belonging to the genus Phlebovirus...
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Effects of Capparis Spinosa extract on the neuropathic pain induced by chronic constriction injury in rats
Neuropathic pain, a chronic pain condition, puts a considerable burden on its patients. However, different pathophysiological characteristics of...
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Unmet needs of drugs for irritable bowel syndrome and inflammatory bowel diseases: interest of vagus nerve stimulation and hypnosis
The gut and the brain communicate bidirectionally through the autonomic nervous system. The vagus nerve is a key component of this gut–brain axis,...
