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New insights into the ontogeny, diversity, maturation and survival of long-lived plasma cells
Plasma cells are unique immune effectors, capable of producing large amounts of high-affinity antibodies that protect against pathogenic infections....
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The impact of age on rectal cancer treatment, complications and survival
BackgroundThe number of older patients with rectal cancer is increasing. Treatment outcome discrepancies persist, despite similar treatment...
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Conditional survival in multiple myeloma and impact of prognostic factors over time
Overall survival estimates from diagnosis are valuable for guiding treatment, but do not consider the years already survived. Conditional survival...
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Proton radiotherapy as a treatment strategy to increase survival in locally advanced pancreatic cancer in the body and tail: a retrospective study
BackgroundLong-term outcomes and prognostic factors of proton radiotherapy for locally advanced pancreatic cancer (LAPC) in the body and tail are...
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Survival outcomes of esophageal cancer patients with recurrence after curative treatments
BackgroundLittle is known about predictive factors for survival outcomes of esophageal carcinoma (EC) patients who developed recurrence after...
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Melanoma and CLL co-occurrence and survival: role of KC history
BackgroundSurvival following melanoma and chronic lymphocytic leukemia (CLL) have both been individually associated with previous history of...
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The long-term survival of the doublet regimen of concurrent chemoradiation therapy for locoregionally advanced nasopharyngeal carcinoma: a retrospective study
ObjectiveThis study introduces innovative strategies, the doublet regimen of concurrent chemoradiotherapy, to ensure longer survival for...
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Integrated In Silico Analysis of Proteogenomic and Drug Targets for Pancreatic Cancer Survival
Pancreatic cancer remains a major health concern, being among the deadliest forms of cancer with over 80% of the patients presenting with metastatic... -
Online decision tools for personalized survival prediction and treatment optimization in elderly patients with lung squamous cell carcinoma: a retrospective cohort study
BackgroundDespite major advances in cancer therapeutics, the therapeutic options of Lung Squamous Cell Carcinoma (LSCC)-specific remain limited....
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Improving communication of cancer survival statistics—feasibility of implementing model-based algorithms in routine publications
BackgroundRoutine reporting of cancer patient survival is important, both to monitor the effectiveness of health care and to inform about prognosis...
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Development and validation of a nomogram for predicting overall survival in patients with sinonasal mucosal melanoma
BackgroundSinonasal mucosal melanoma (SNMM) is a relatively rare malignant tumour with a poor prognosis. This study was designed to identify...
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Clinical characteristics and survival outcomes in patients with ovarian strumal carcinoid
BackgroundOvarian strumal carcinoid is an extremely rare ovarian malignant tumor with limited data on clinical characteristics and survival outcomes.
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Recursive partitioning analysis for survival stratification and early imaging prediction of molecular biomarker in glioma patients
BackgroundGlioma is the most common primary brain tumor with high mortality and disability rates. Recent studies have highlighted the significant...
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Microbiological risk factors, ICU survival, and 1-year survival in hematological patients with pneumonia requiring invasive mechanical ventilation
PurposeTo identify pathogenic microorganisms and microbiological risk factors causing high morbidity and mortality in immunocompromised patients...
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Determinants of survival and retrospective comparisons of 183 clinical trial patients with myelofibrosis treated with momelotinib, ruxolitinib, fedratinib or BMS- 911543 JAK2 inhibitor
Between October 2007 and July 2013, 183 Mayo Clinic patients (median age 65 years; 58% males) with high/intermediate risk myelofibrosis (MF) were...
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Socio-economic and ethnic disparities in childhood cancer survival, Yorkshire, UK
BackgroundEstablishing the existence of health inequalities remains a high research and policy agenda item in the United Kingdom. We describe ethnic...
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Patients with metastatic renal cell carcinoma who receive immune-targeted therapy may derive survival benefit from nephrectomy
BackgroundNephrectomy, whether in the era of cytokine therapy or targeted therapy, has an important role in the treatment of metastatic renal cell...
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Transformation and survival in marginal zone lymphoma: a Finnish nationwide population-based study
Marginal zone lymphoma (MZL) is an indolent B-cell malignancy with heterogeneous anatomical and clinical presentation. While MZLs are generally...
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Overall survival following stereotactic radiosurgery for ten or more brain metastases: a systematic review and meta-analysis
BackgroundBrain metastases are the most common intracranial tumours. Variation exists in the use of stereotactic radiosurgery for patients with 10 or...
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The impact of race on survival in metastatic prostate cancer: a systematic literature review
BackgroundProstate cancer (PC) is the second most diagnosed cancer in men worldwide. While racial and ethnic differences exist in incidence and...